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ClinicalTrials.gov public records Last synced Oct 17, 2026, 12:03 PM EDT

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Showing 1345–1368 of 1,571 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Wake Forest University Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Molecular Transducers of Physical Activity Consortium (MoTrPAC) - Pediatric Protocol

NCT04151199
View directory record Official record
Conditions
Physical Activity
Interventions
EE Training
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
10 Years to 17 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Recruiting Not applicable Interventional

CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)

NCT05897632
View directory record Official record
Conditions
Chest Pain
Interventions
Outpatient Evaluation, Hospitalization Evaluation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Detroit, Michigan • Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Withdrawn No phase listed Observational

Continuous Hemoglobin Monitoring: Detection of Acute Blood Loss - Accurate, Timely and Cost-effective

NCT02138175
View directory record Official record
Conditions
Bleeding, Acute Blood Loss Anemia
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Virtual Visits (Utilization of Virtual Care in Postoperative Patients to Improve the Patient Experience)

NCT03258177
View directory record Official record
Conditions
Appendectomy, Laparoscopic, Cholecystectomy, Laparoscopic, Cholecystectomy, Robotic
Interventions
Virtual Visit
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Phase 1 Interventional

Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinA

NCT05769478
View directory record Official record
Conditions
Botulism, Iatrogenic Botulism
Interventions
Amifampridine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CONNECTing Head and Neck Caregivers to Supportive Care Resources

NCT03875885
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
CONNECT, CONTROL
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial

NCT03139838
View directory record Official record
Conditions
Critical Illness
Interventions
EHR-Based Intervention A, EHR-Based Intervention B
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
10
States / cities
Albemarle, North Carolina • Charlotte, North Carolina • Lincolnton, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 17, 2026, 12:03 PM EDT
Completed No phase listed Observational

Oral Aromatase Inhibitors Modify the Gut Microbiome

NCT05030038
View directory record Official record
Conditions
Breast Cancer
Interventions
Fecal swab collection, Blood samples
Biological
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Phase 2 Interventional

Denileukin Diftitox in Treating Patients With Fludarabine-Refractory B-Cell Chronic Lymphocytic Leukemia

NCT00082940
View directory record Official record
Conditions
Leukemia
Interventions
denileukin diftitox
Biological
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
11
States / cities
Orange, California • Chicago, Illinois • Vincennes, Indiana + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Oct 17, 2026, 12:03 PM EDT
Terminated Phase 2 Interventional Results available

Combined Spinal/Epidural (CSE) Saline Duration/Spread

NCT01062893
View directory record Official record
Conditions
Labor Pain
Interventions
Sterile normal saline 0 mls, 15 mls sterile normal saline
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
12 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Oct 17, 2026, 12:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Values Affirmation to Improve Teachers' Outcomes

NCT04241055
View directory record Official record
Conditions
Psychological
Interventions
Values affirmation exercise, Active control exercise
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 17, 2026, 12:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health Outcomes After Participating in Exercise (HOPE)

NCT03430115
View directory record Official record
Conditions
Weight Loss, Obesity, Aging
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 17, 2026, 12:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Valence-based Effects in Self-Monitoring Feedback Messages

NCT07292389
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Positive Reinforcement, Positive Reinforcement + Areas for Change
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Phase 4 Interventional Results available

Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction

NCT00982033
View directory record Official record
Conditions
Heart Failure
Interventions
aliskiren, placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Oct 17, 2026, 12:03 PM EDT
Active, not recruiting No phase listed Observational

Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department

NCT06899776
View directory record Official record
Conditions
ACS (Acute Coronary Syndrome)
Interventions
Abbott i-STAT point of care (POC) device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Charlotte, North Carolina • High Point, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Phase 1 Interventional Results available

Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02971397
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
Bone Marrow Aspiration and Biopsy, Cytarabine, Daunorubicin Hydrochloride, Laboratory Biomarker Analysis
Procedure · Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Terminated Not applicable Interventional Results available

Metabolic and Microbial Profiling of Lung Cancer

NCT03998189
View directory record Official record
Conditions
Nonsmall Cell Lung Cancer, Nonsmall Cell Lung Cancer Stage
Interventions
Breath Collection, Saliva Collection, Blood Collection, Urine Collection, Tumor Collection, Medical History Data Collection
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2021 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health)

NCT04076618
View directory record Official record
Conditions
Weight Loss, Bone Health
Interventions
Vest, Resistance Exercise Training, weight loss program
Device · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension

NCT01658657
View directory record Official record
Conditions
Hypertension, Plasma Renin Activity
Interventions
Hydrochlorothiazide, Lisinopril, Amlodipine, metoprolol, lisinopril/hydrochlorothiazide
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2015 · Synced Oct 17, 2026, 12:03 PM EDT
Completed No phase listed Observational

Food Security and Perceptions and Barriers to Healthy Eating in Individuals With Spinal Cord Injuries

NCT03457558
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
149 participants
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional

REJOIN Trial for Older Breast Cancer Survivors

NCT03955627
View directory record Official record
Conditions
Breast Cancer Female
Interventions
Relieving Joint Pain and Improving AI Adherence in Older Breast Cancer Survivors (REJOIN)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

NCT04096170
View directory record Official record
Conditions
Hernia, Paraesophageal
Interventions
IV lidocaine, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 17, 2026, 12:03 PM EDT
Withdrawn Not applicable Interventional

Reconditioning Exercise for COVID-19 Patients Experiencing Residual sYmptoms

NCT04958161
View directory record Official record
Conditions
Covid19
Interventions
Exercise Therapy
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 17, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids

NCT05503186
View directory record Official record
Conditions
Opioid Misuse
Interventions
Text Message, Standard of Care
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
479 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 17, 2026, 12:03 PM EDT