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ClinicalTrials.gov public records Last synced Oct 30, 2026, 9:57 AM EDT

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Showing 1393–1416 of 1,902 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Yale University Clear all
Terminated Early Phase 1 Interventional

Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study

NCT04218773
View directory record Official record
Conditions
Ischemic Stroke, Blood Pressure
Interventions
Phenylephrine, Norepinephrine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional

New Mechanisms of Obesity

NCT06768827
View directory record Official record
Conditions
Obesity and Overweight, Insulin Resistance, Obesity and Obesity-related Medical Conditions
Interventions
Lactulose Oral Product
Other
Lead sponsor
Yale University
Other
Eligibility
15 Years to 22 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Phase 2 Interventional Results available

Irinotecan -Eluting LC Bead-M1 (DEBIRI-M1) for Patients With Liver Metastases From Colorectal Cancer

NCT02015754
View directory record Official record
Conditions
Colorectal Cancer
Interventions
DEBIRI, LC Bead M1, TACE
Drug · Device · Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Evaluating the Safety, Tolerability, Pharmacokinetics and Receptor Occupancy of BMS-984923

NCT04805983
View directory record Official record
Conditions
Alzheimer Disease
Interventions
BMS-984923
Drug
Lead sponsor
Yale University
Other
Eligibility
50 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Not applicable Interventional Results available

LGBTQ-affirmative CBT for Youth

NCT05408858
View directory record Official record
Conditions
Anxiety Disorders, Depression, LGBTQ
Interventions
LGBTQ-affirmative cognitive behavioral group therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 17 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2024 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Phase 2 Interventional Results available

Translational Neuroscience Optimization of GlyT1 Inhibitor

NCT01911676
View directory record Official record
Conditions
Cognitive Impairments Associated With Schizophrenia
Interventions
PF-03463275, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PET Imaging of mGLuR5 With Drug Challenge

NCT01691092
View directory record Official record
Conditions
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
Interventions
Ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 30, 2026, 9:57 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy

NCT00920309
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney Disease
Interventions
Rapamycin, Standard of Care-Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 30, 2026, 9:57 AM EDT
Completed No phase listed Observational

Gocheck Kids vs. Welch Allyn Spot Vision Screener

NCT04321538
View directory record Official record
Conditions
Amblyopia
Interventions
Gocheck Kids, Welch Allyn Spot Vision Screener, Physical Exam
Device · Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
1 Year to 7 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 30, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder

NCT06142955
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
MAGSTIM Rapid2 TMS system
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Functional MRI of Stress in Obesity

NCT01719484
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2022 · Synced Oct 30, 2026, 9:57 AM EDT
Active, not recruiting Early Phase 1 Interventional

AB154 Combined With AB122 for Recurrent Glioblastoma

NCT04656535
View directory record Official record
Conditions
Glioblastoma
Interventions
Zimberelimab, Domvanalimab, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
San Francisco, California • New Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cannabinoids and Cerebellar-Motor Functioning

NCT01853020
View directory record Official record
Conditions
Cannabis, Psychotic Disorders
Interventions
THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 35 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 30, 2026, 9:57 AM EDT
Terminated Not applicable Interventional

Cognitive-Behavioral and Physical Activity Interventions for Binge Eating and Overweight

NCT03777189
View directory record Official record
Conditions
Binge-Eating Disorder, Binge Eating, Overweight and Obesity
Interventions
Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Oct 30, 2026, 9:57 AM EDT
Active, not recruiting Not applicable Interventional

The Preoperative Health & Body Study

NCT01516190
View directory record Official record
Conditions
Breast Cancer
Interventions
Exercise, Surgical preparation program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Early Phase 1 Interventional Results available

The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders

NCT03953612
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Pregnenolone (PREG), Placebos
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 30, 2026, 9:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

NCT07488819
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, PTSD, Alcohol Use Disorder (AUD)
Interventions
PF974
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2032
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Recruiting Not applicable Interventional

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

NCT05932745
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Not applicable Interventional Results available

Perinatal Attentional Retraining Intervention for Smoking for Minority Women

NCT04114877
View directory record Official record
Conditions
Postpartum Smoking Relapse
Interventions
Attentional retraining (AR), Visual probe (VP)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Exploratory Study Using Positron Emission Tomography With TS-121 and [11C]TASP0410699 in Healthy Adult Male Subjects

NCT02448212
View directory record Official record
Conditions
Healthy
Interventions
TS-121, [11C]TASP0410699, Positron Emission Tomography (PET)
Drug · Radiation
Lead sponsor
Taisho Pharmaceutical R&D Inc.
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Delta-9-THC and Iomazenil in Healthy Humans

NCT00982982
View directory record Official record
Conditions
Schizophrenia, Mental Disorders, Psychotic Disorders
Interventions
THC and Iomazenil, Placebo (control)
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Not applicable Interventional

Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder

NCT02003820
View directory record Official record
Conditions
Autism Spectrum Disorder, Dental Caries
Interventions
video modeled social story
Behavioral
Lead sponsor
Yale University
Other
Eligibility
5 Years to 14 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Oct 30, 2026, 9:57 AM EDT
Completed Phase 3 Interventional

Levetiracetam Treatment of Tardive Dyskinesia

NCT00291213
View directory record Official record
Conditions
Tardive Dyskinesia
Interventions
levetiracetam, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 6, 2014 · Synced Oct 30, 2026, 9:57 AM EDT
Not listed No phase listed Observational

Improving Treatment and Recovery Services for Individuals With Opioid Problems

NCT05129813
View directory record Official record
Conditions
Counseling
Interventions
Recovery Guide Counseling
Behavioral
Lead sponsor
Howard University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Oct 30, 2026, 9:57 AM EDT