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ClinicalTrials.gov public records Last synced Oct 17, 2026, 5:21 AM EDT

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Showing 121–144 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Spaulding Rehabilitation Hospital Clear all
Recruiting Not applicable Interventional

Combination Therapy to Improve SCI Recovery.

NCT05563103
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Daily acute intermittent hypoxia, Room air (SHAM), Walking + tSTIM, Walking + Sham transcutaneous spinal stimulation (tSHAM)
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Terminated Not applicable Interventional

Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity

NCT04742257
View directory record Official record
Conditions
Muscle Spasticity, Stroke
Interventions
MyoRegulator® device
Device
Lead sponsor
PathMaker Neurosystems Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cambridge, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Multimodality Intervention for Function and Metabolism in SCI

NCT03576001
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Testosterone Undecanoate, hybrid exercise
Drug · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
19 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02330315
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 17, 2026, 5:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

NCT02323945
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
AIH, Walk, Strength
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Terminated No phase listed Observational

An In-Shoe Device to Monitor Toe-Walking in Children With Cerebral Palsy

NCT01684254
View directory record Official record
Conditions
Children With Cerebral Palsy
Interventions
Not listed
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 17, 2026, 5:21 AM EDT
Recruiting Phase 1Phase 2 Interventional

Modulating Exercise Dosage to Improve Concussion Recovery

NCT05434130
View directory record Official record
Conditions
Concussion, Brain, Treatment, Aerobic Exercise, Inflammation, Depression, Anxiety
Interventions
High Dose Exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 18 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Optimized tDCS for Fibromyalgia: Targeting the Endogenous Pain Control System

NCT03371225
View directory record Official record
Conditions
Fibromyalgia
Interventions
Active tDCS, Active Exercise, Sham tDCS, Sham Exercise
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study

NCT00779324
View directory record Official record
Conditions
Brain Injury, Aggression
Interventions
Amantadine Hydrochloride, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
16 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
6
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Charlotte, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Oct 17, 2026, 5:21 AM EDT
Not listed Not applicable Interventional

Effect of Lifestyle Changes on BDNF Level After Stroke

NCT03701815
View directory record Official record
Conditions
Stroke
Interventions
Wellness in Rehabilitation program
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
30 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional

Structural Integration for Chronic Low Back Pain

NCT01322399
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Structural Integration, Usual care
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 10, 2013 · Synced Oct 17, 2026, 5:21 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Investigating Motor Cortex Processing for Pain Modulation

NCT01404039
View directory record Official record
Conditions
Motor Activity
Interventions
Motor Learning, Somatosensory Learning, Observational Task, Mental Imagery, transcranial direct current stimulation
Behavioral · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exploration of Blood Flow Regulation to Bone in Humans

NCT04083794
View directory record Official record
Conditions
Bone Blood Flow Regulation
Interventions
Laboratory based assessments
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury

NCT03267212
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Non-invasive ventilation(NIV), Sham Non-invasive ventilation(NIV), Functional Electrical Stimulation Row Training (FESRT)
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

VR Cognitive Rehabiliation for Pediatric TBI

NCT04526639
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Virtual Reality-based Interactive Cognitive Training Program, Placebo Virtual Reality Game
Behavioral
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
Up to 18 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Noninvasive Brain Stimulation in Parkinson's Disease

NCT01113086
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
40 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mindfulness Based Stress Reduction on Patients With Traumatic Brain Injury

NCT01613872
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injury, Stress
Interventions
Mindfulness Based Stress Reduction
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
30 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Slow Yogic-Derived Breathing and Respiration and Cardiovascular Variability in Spinal Cord Injury Patients

NCT05480618
View directory record Official record
Conditions
Spinal Cord Injuries, Slow Breathing
Interventions
Slow Breathing
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Completed No phase listed Observational Results available

FES-Rowing: Preventing the Secondary Conditions of Paralysis Through Vigorous Exercise

NCT05144113
View directory record Official record
Conditions
Paralysis, Legs
Interventions
Survey subjects to discover their motivations, preferences and challenges pertaining to participation in physical activity in general and FES-rowing.
Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 17, 2026, 5:21 AM EDT
Active, not recruiting Phase 2 Interventional

Deploying Digital Prosthetic Interface Technology and Exercise in Dysvascular Amputees

NCT05656924
View directory record Official record
Conditions
Diabetes Type 2, Amputation
Interventions
digital prosthetic interface technology
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 17, 2026, 5:21 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Vasomotor Symptoms and Cardiovascular Control

NCT02202707
View directory record Official record
Conditions
Vasomotor Symptoms, Cardiovascular Health
Interventions
Gabapentin
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
45 Years to 58 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Effects of LEDs on Memory in TBI Patients

NCT01598532
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
MedX Health Phototherapy (light therapy)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 17, 2026, 5:21 AM EDT
Completed Not applicable Interventional Results available

Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information

NCT00401414
View directory record Official record
Conditions
Pulmonary Embolism, Deep Vein Thrombosis, Atrial Fibrillation
Interventions
Warfarin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 30, 2013 · Synced Oct 17, 2026, 5:21 AM EDT
Recruiting Not applicable Interventional

Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia

NCT06360900
View directory record Official record
Conditions
Functional Dyspepsia
Interventions
Sensory device, Skills Building, Health Education, Subsensory device
Device · Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 17, 2026, 5:21 AM EDT