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Showing 169–192 of 233 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pharmacogenetics of Alcohol: Treatment Implications

NCT00734656
Conditions
Alcohol Related Disorders, Alcoholism, Alcohol Abuse
Interventions
dutasteride + ethanol, placebo medication + ethanol, dutasteride + placebo alcohol, placebo medication + placebo alcohol
Drug
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 45 Years · Male only
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Periodontitis, Chronic Kidney Disease
Interventions
Scaling root planing, Supragingival Prophylaxis
Procedure
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Farmington, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems

NCT05080777
Conditions
Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurocognitive Disorders, Neurodegenerative Diseases, Mental Disorders
Interventions
Tele-Savvy, Caregiving During Crisis (Educational Program)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 110 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Farmington, Connecticut • Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Manipulating Tobacco Constituents in Male Menthol Smokers

NCT02592772
Conditions
Nicotine Dependence
Interventions
Reduced Nicotine Non-Menthol (RNC), Reduced Nicotine Menthol (RNC-Men), Conventional Nicotine Non-Menthol (CN)
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Farmington, Connecticut • Hartford, Connecticut
Not yet recruiting Not applicable Interventional

Opioid Package Prototype (OPP)

NCT04598074
Conditions
Opioid Use, Opioid Prescribing, Dispensing, and Patient Use
Interventions
Opioid Package Prototype (OPP), Usual Care (standard amber vial)
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Dementia, Depression, Delirium
Interventions
Home Based Care Team, Telephone Based Care Team
Other
Lead sponsor
UConn Health
Other
Eligibility
65 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Gambling, Mental Health
Interventions
Cognitive behavior therapy, Contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Cancer-related Fatigue
Interventions
Thyrotropin releasing hormone (TRH), Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Completed Not applicable Interventional

Trauma-Informed Mindfulness-Based Yoga

NCT03581461
Conditions
Trauma
Interventions
Trauma-Informed Mindfulness-Based Yoga
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
13 Years to 21 Years · Male only
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
beta blocker discontinuation
Other
Lead sponsor
UConn Health
Other
Eligibility
50 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Farmington, Connecticut
Active, not recruiting Not applicable Interventional

Promoting Employment in Persons Living With HIV/AIDS

NCT03959826
Conditions
Unemployment, HIV
Interventions
activity contracting, contingency management for activity completion
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Middletown, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Electronic Cigarettes on Nicotine Concentrations

NCT01775787
Conditions
Health Behavior
Interventions
Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Breast Neoplasms
Interventions
Heat Shock Protein 70-peptide complexes (HSP70)
Biological
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Contrast Enhanced Images vs. Non-contrast Images, Gadopiclinol Enhanced Images vs. Gadobutrol Enhanced Images
Interventions
Gadopiclenol, Gadobutrol (Gadavist, BAY86-4875)
Drug
Lead sponsor
UConn Health
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Farmington, Connecticut
Recruiting No phase listed Observational Accepts healthy volunteers

Circulating Markers for Ischemic Heart Disease

NCT00762333
Conditions
Myocardial Infarction, Ischemia, Congestive Heart Failure
Interventions
Not listed
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2027
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Childhood Obesity
Interventions
Sugar-sweetened beverage reduction education for preschool children
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Substance Abuse
Interventions
Contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Recruiting No phase listed Observational Accepts healthy volunteers

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

NCT04321512
Conditions
Myocardial Infarction, Stroke, Ischemic, Ischemia
Interventions
There is no intervention given to the subjects
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2027
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Cocaine Dependence
Interventions
Contingency Management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Farmington, Connecticut
Terminated Phase 4 Interventional Results available

Early Antibiotics After Aspiration in ICU Patients

NCT05079620
Conditions
Aspiration, Aspiration Pneumonia
Interventions
Ceftriaxone, Amoxicillin clavulanic acid, Cefepime, Vancomycin, Levofloxacin
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Lower Urinary Tract Symptoms, Overactive Bladder Syndrome
Interventions
MitoQ (mitoquinol mesylate), Placebo
Drug · Other
Lead sponsor
Iman Al-Naggar, PhD
Other
Eligibility
50 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Major Depressive Disorder
Interventions
Telephonic CBT, Wait List Control
Behavioral
Lead sponsor
iHope Network, Inc.
Industry
Eligibility
12 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Farmington, Connecticut • Woburn, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

NCT00802321
Conditions
Alcohol Related Disorders, Alcoholism, Alcohol Abuse
Interventions
Dutasteride
Drug
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 55 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Farmington, Connecticut