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ClinicalTrials.gov public records Last synced Oct 13, 2026, 5:53 PM EDT

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Showing 169–192 of 872 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University of Iowa Clear all
Completed No phase listed Observational

Genetic Risk Assessment of Defibrillator Events

NCT02045043
View directory record Official record
Conditions
Sudden Cardiac Death, Arrhythmias, Congestive Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
1,807 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
6
States / cities
Atlanta, Georgia • Boston, Massachusetts • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2014 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects

NCT00928135
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Xylitol, Hypertonic saline
Drug
Lead sponsor
Joseph Zabner
Other
Eligibility
12 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 13, 2026, 5:53 PM EDT
Completed No phase listed Observational

Retinal Therapy Guided by 3D OCT Image Analysis

NCT02308215
View directory record Official record
Conditions
Age-Related Macular Degeneration, Choroidal Neovascularization
Interventions
Not listed
Lead sponsor
Michael Abramoff
Other
Eligibility
45 Years to 120 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Inhaled Cannabis on Driving Performance

NCT01620177
View directory record Official record
Conditions
Alcohol Drinking, Cannabis
Interventions
Alcohol(oral) and placebo, Cannabis(THC)(Inhaled) and Placebo
Drug
Lead sponsor
Gary R Gaffney
Other
Eligibility
21 Years to 55 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 13, 2026, 5:53 PM EDT
Active, not recruiting Phase 2 Interventional

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

NCT02344355
View directory record Official record
Conditions
Glioblastoma Multiforme
Interventions
Temozolomide, radiation therapy, Ascorbic Acid
Drug · Radiation
Lead sponsor
Bryan Allen
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 13, 2026, 5:53 PM EDT
Completed No phase listed Observational

Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue Sarcoma

NCT02897128
View directory record Official record
Conditions
Sarcoma, Soft Tissue
Interventions
Observational Only - Transcutaneous Oxygen Measurement
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Gainesville, Florida • Iowa City, Iowa • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Intraoperative Infection Transmission in the Pediatric Operating Room

NCT03992209
View directory record Official record
Conditions
Health Care Associated Infection, Hand Hygiene
Interventions
Standard care, Protocolized care
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
1 Year to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2022 · Synced Oct 13, 2026, 5:53 PM EDT
Not listed Phase 3 Interventional

MD.2 Medication Dispenser Medication Adherence Study

NCT00560001
View directory record Official record
Conditions
Frail Elderly, Medication Errors
Interventions
MD.2 Medication Dispenser
Behavioral
Lead sponsor
Interactive Medical Developments
Industry
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 8, 2009 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Results available

Domperidone for the Treatment of Chronic Nausea and Vomiting Secondary to Gastroparesis

NCT01711918
View directory record Official record
Conditions
Patients With Gastroparesis Who Have Failed Standard Therapy
Interventions
Domperidone
Drug
Lead sponsor
Ron Schey
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Residential MapTrek- Increasing Physical Activity Among Older Adults in a Residential-Living

NCT04041869
View directory record Official record
Conditions
Sedentary Behavior
Interventions
MapTrek
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
25 Years to 100 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Altering Narcotic Prescription Methods Affect Opioid Distribution Following Select Upper Extremity Surgeries?

NCT03570320
View directory record Official record
Conditions
Opioid Use
Interventions
Modification of opioid prescription method
Other
Lead sponsor
John Yanik
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 13, 2026, 5:53 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Chronic Lung Allograft Dysfunction MRI Study

NCT06406777
View directory record Official record
Conditions
Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Interventions
Spirometry, Contrast Lung Computed Tomography (CT) Scan, Oxygen enhanced magnetic resonance imaging (OE-MRI) Scan, 129Xe MRI scans
Diagnostic Test · Drug
Lead sponsor
Sean Fain
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants

NCT04292301
View directory record Official record
Conditions
MRI
Interventions
STrategically Acquired Gradient Echo (STAGE)
Device
Lead sponsor
SpinTech, Inc.
Other
Eligibility
6 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Loma Linda, California • Los Gatos, California • Iowa City, Iowa + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 13, 2026, 5:53 PM EDT
Terminated Not applicable Interventional

Transcorporal Versus Standard Artificial Urinary Sphincter Placement

NCT02591381
View directory record Official record
Conditions
Urinary Stress Incontinence
Interventions
Artificial Urinary Sphincter Placement
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2018 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Efficacy of Brief Acceptance and Commitment Therapy (ACT) for Perinatal Anxiety

NCT03837392
View directory record Official record
Conditions
Post Partum Depression, Perinatal Depression, Post Partum Anxiety, Perinatal Anxiety
Interventions
Baseline Assessment (18-26 weeks pregnant), Online Intervention and Phone Coaching Interventions, Follow Up Assessments: 34-36 weeks pregnant and 4-week postpartum, Follow Up Assessments: 8 weeks postpartum
Diagnostic Test · Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 13, 2026, 5:53 PM EDT
Completed No phase listed Observational

Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy

NCT01129687
View directory record Official record
Conditions
Neuroma, Acoustic
Interventions
Microsurgery, Stereotactic radiation therapy
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2022
U.S. locations
9
States / cities
Stanford, California • Washington D.C., District of Columbia • Indianapolis, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Effects of School Gardens on Children's Diet, Nutritional Knowledge, Etc.

NCT02166034
View directory record Official record
Conditions
Dietary Habits
Interventions
garden intervention
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
6 Years to 14 Years
Enrollment
3,531 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Little Rock, Arkansas • Osceola, Iowa • Ithaca, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2014 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inorganic Nitrate and OSA

NCT03930563
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Pre-beetroot juice supplementation, Post-beetroot juice supplementation
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Human Lung Responses to Respiratory Pathogens

NCT01967628
View directory record Official record
Conditions
Respiratory Infection
Interventions
Vitamin D3 (cholecalciferol), Placebo Sugar Pill
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional

Improving STEM Outcomes for Young Children With Language Learning Disabilities Via Telehealth

NCT04775199
View directory record Official record
Conditions
Language Development Disorders
Interventions
Language Intervention
Behavioral
Lead sponsor
Karla McGregor
Other
Eligibility
4 Years to 7 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 13, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional

Progressive Achilles Loading Via Clinician E-support

NCT06736795
View directory record Official record
Conditions
Achilles Tendon Pain, Achilles Tendinopathy
Interventions
Exercise, Education
Other
Lead sponsor
Ruth Chimenti
Other
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Iowa City, Iowa • Fort Cavazos, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 13, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Opioid Consumption and Disposal After Shoulder Arthroplasty

NCT05525975
View directory record Official record
Conditions
Opioid Use
Interventions
Educational materials
Other
Lead sponsor
Brendan M. Patterson
Other
Eligibility
21 Years to 99 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 13, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional

T2 Star Magnetic Resonance Imaging and Biomarker Blood Testing to Predict the Change and Progress of Malignant Gliomas

NCT07447531
View directory record Official record
Conditions
Malignant Glioma
Interventions
T2 (Observed)-Weighted Imaging, Biospecimen Collection, Magnetic Resonance Imaging
Procedure
Lead sponsor
John M. Buatti
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 13, 2026, 5:53 PM EDT
Recruiting Early Phase 1 Interventional

Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral Sclerosis

NCT07224269
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Adenosine Triphosphate Activities
Interventions
Terazosine, Placebo
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 13, 2026, 5:53 PM EDT