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ClinicalTrials.gov public records Last synced Sep 30, 2026, 9:18 PM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: AO Innovation Translation Center Clear all
Active, not recruiting No phase listed Observational

Metastatic Tumor Research and Outcomes Network

NCT02830451
View directory record Official record
Conditions
Metastatic Spine Tumor
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
960 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
10
States / cities
San Francisco, California • Chicago, Illinois • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

NCT02827214
View directory record Official record
Conditions
Thoracolumbar Burst Fracture
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
San Diego, California • East Syracuse, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Sep 30, 2026, 9:18 PM EDT
Terminated Not applicable Interventional

AO Multicenter Intervention Trial for Prevention of Surgical Site Infection

NCT03380273
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Implementation of the AO Trauma SSI Prevention Bundle
Behavioral
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years to 100 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
8
States / cities
Los Angeles, California • Lexington, Kentucky • Worcester, Massachusetts + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Geriatric Fracture Centers - Evaluation of a Geriatric Co-management Program

NCT02297581
View directory record Official record
Conditions
Hip Fractures
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
70 Years and older
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
St Louis, Missouri • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Sep 30, 2026, 9:18 PM EDT
Active, not recruiting No phase listed Observational

Orbital Fractures Registry

NCT03887988
View directory record Official record
Conditions
Orbital Fractures, Blow Out Fracture of Orbit
Interventions
Primary "early" reconstruction, Nonsurgical, Primary "delayed" reconstruction, Secondary reconstruction
Procedure · Other
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 30, 2026, 9:18 PM EDT
Not listed No phase listed Observational

Medication-related Osteonecrosis of the Jaw (MRONJ) Registry

NCT02932501
View directory record Official record
Conditions
Medication-related Osteonecrosis of the Jaw, Bisphosphonate-Associated Osteonecrosis of the Jaw
Interventions
Conservative treatment, Surgical treatment, Adjuvant non-surgical treatment
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Sep 30, 2026, 9:18 PM EDT
Terminated Phase 4 Interventional

Surgical Plate Osteosynthesis of Distal Radius Fractures

NCT00205998
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Locking Compression Plate 2,4mm, Locking Compression Plate 3,5mm
Device
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2007 · Synced Sep 30, 2026, 9:18 PM EDT
Completed Not applicable Interventional

A Multicenter RCT to Investigate the Treatment of Double (Bilateral) Mandibular Fractures

NCT02341443
View directory record Official record
Conditions
Mandibular Fractures
Interventions
Implants
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
New York, New York • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Bilateral Condylar Fractures Registry

NCT02884765
View directory record Official record
Conditions
Bilateral Condylar Fracture of the Mandible
Interventions
Non-surgical, Non-surgical / Surgical, Surgical
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years to 90 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Lexington, Kentucky • Louisville, Kentucky • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Sep 30, 2026, 9:18 PM EDT
Active, not recruiting No phase listed Observational

Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®

NCT04113044
View directory record Official record
Conditions
Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal, Distal Radius Fracture
Interventions
All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
Other
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Timeline
2021 – 2026
U.S. locations
4
States / cities
Los Angeles, California • Miami, Florida • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Sep 30, 2026, 9:18 PM EDT
Recruiting No phase listed Observational

An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects

NCT04112992
View directory record Official record
Conditions
Limb Fracture, Bone Loss
Interventions
Any treatment that is used for a defect of any long bone
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Prospective Multicenter Trial to Compare Preformed vs Non Preformed Orbital Implants

NCT01121159
View directory record Official record
Conditions
Orbital Floor Fracture, Medial Orbital Wall Fracture
Interventions
orbital fracture repair
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

The Influence of Local Bone Status on Complications After Surgical Treatment of Distal Radius Fractures

NCT01144208
View directory record Official record
Conditions
Distal Radius Fractures, Poor Bone Quality, Treatment Complications
Interventions
Not listed
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
50 Years to 90 Years
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2010 · Synced Sep 30, 2026, 9:18 PM EDT
Terminated No phase listed Observational

A Multicenter Prospective Registry for the Management of Degenerative Spine Disorders

NCT02802033
View directory record Official record
Conditions
Degenerative Diseases, Spinal Cord
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
908 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Prospective Evaluation of Elderly Deformity Surgery

NCT02035280
View directory record Official record
Conditions
Adult Spinal Deformity
Interventions
Not listed
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
60 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
5
States / cities
San Francisco, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Sep 30, 2026, 9:18 PM EDT
Recruiting No phase listed Observational

Case Series on the Clinical Performance of VA Clavicle and Clavicle Hook Plate 2.7 Systems

NCT04921865
View directory record Official record
Conditions
Clavicle, Acromioclavicular Joint, Fracture
Interventions
DPS VA-LCP® Clavicle Plate 2.7 System; DPS VA-LCP® Clavicle Hook Plate 2.7 System
Device
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
3
States / cities
Grand Rapids, Michigan • Winston-Salem, North Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Recruiting No phase listed Observational

Periprosthetic Fracture Registry (PPFx)

NCT03378557
View directory record Official record
Conditions
Periprosthetic Fractures, Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Columbia, Missouri • Jersey City, New Jersey • Livingston, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Recruiting No phase listed Observational

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

NCT04098146
View directory record Official record
Conditions
Mandibular Reconstruction, Segmental Mandibular Defects
Interventions
Surgical Resection and Reconstruction
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2022 – 2030
U.S. locations
5
States / cities
Jacksonville, Florida • Chicago, Illinois • New Hyde Park, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Pediatric Femur Fracture Registry

NCT03211546
View directory record Official record
Conditions
Femoral Shaft Fracture
Interventions
Conservative (non-surgical) treatment, Surgical treatment
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
Up to 16 Years
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Focused Registry to Collect Clinical Data on the MatrixWAVE System

NCT03405389
View directory record Official record
Conditions
Mandibular Fractures
Interventions
MatrixWAVE MMF System
Procedure
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 30, 2026, 9:18 PM EDT
Terminated No phase listed Observational

Prospective Multicenter Registry for Use of the MAXFRAME™ Multiaxial Correction System

NCT04017065
View directory record Official record
Conditions
Limb Deformities Congenital, Limb Deformities Nos (Acquired), Deformity of Bone
Interventions
DePuy Synthes MAXFRAMETM system
Device
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Sep 30, 2026, 9:18 PM EDT
Active, not recruiting No phase listed Observational

Fragility Fractures of the Pelvis (FFP)

NCT04182776
View directory record Official record
Conditions
Pelvic Fracture
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
65 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Clinical Experience With the Hindfoot Arthrodesis Nail for the Surgical Treatment of Ankle and Hindfoot Pathologies

NCT00942032
View directory record Official record
Conditions
Hindfoot Arthrodesis, Hindfoot Pathologies
Interventions
Not listed
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Rancho Mirage, California • Charleston, South Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2011 · Synced Sep 30, 2026, 9:18 PM EDT
Completed No phase listed Observational

Performance Improvement Program on Imaging II

NCT02272972
View directory record Official record
Conditions
Hip Fractures, Femoral Fractures, Fractures, Bone
Interventions
Application of knowledge
Other
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 30, 2026, 9:18 PM EDT