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ClinicalTrials.gov public records Last synced Oct 7, 2026, 12:31 AM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.

Filters: Sponsor: Alexza Pharmaceuticals, Inc. Clear all

Conditions: Schizophrenia
Interventions: Inhaled Placebo, Inhaled Loxapine 5 mg, Inhaled Loxapine 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Upland, California

Conditions: Smoking, Cigarette
Interventions: Inhaled Loxapine 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 20 Years to 50 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: Breakthrough Pain
Interventions: Inhaled Placebo, Inhaled Fentanyl 25 mcg, Intravenous Fentanyl 25 mcg, Inhaled Fentanyl 25 mcg x 2, Inhaled Fentanyl 25 mcg x 4, Inhaled Fentanyl 25 mcg x 6, Inhaled Fentanyl 25 mcg x 12; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Agitation,Psychomotor
Interventions: Loxapine 10 MG; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Migraine Headache, With or Without Aura
Interventions: Staccato Placebo, Staccato Prochlorperazine 5 mg, Staccato Prochlorperazine 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Mount Vernon, New York

Conditions: Cyclic Vomiting Syndrome
Interventions: 3mg AZ-010, 1mg AZ010, Staccato Placebo; Combination Product
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 18
States / cities: Lancaster, California • Los Angeles, California • San Diego, California + 14 more

Conditions: Asthma
Interventions: Inhaled loxapine @ 0 & 10 h, Inhaled placebo @ 2 & 10 hours; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: San Diego, California

Conditions: Volunteers on Chronic, Stable Antipsychotic Regimens
Interventions: A - 10 mg loxapine q 4 h x 3 (30 mg total), B - 10 mg x 1, 5 mg x 2 loxapine q 4 h (20 mg total), C - 5 mg loxapine q 4 h x 3 (15 mg total), D - inhaled placebo q 4 h x 3; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Parkinson Disease
Interventions: Apomorphine Cartridge; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 30 Years to 85 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 13
States / cities: Scottsdale, Arizona • Tucson, Arizona • Fountain Valley, California + 10 more

Conditions: Schizophrenia
Interventions: inhaled Loxapine 0.625 mg, inhaled Loxapine 1.25 mg, inhaled Loxapine 2.5 mg, inhaled Loxapine 5 mg, inhaled Loxapine 10 mg, inhaled Placebo (0 mg); Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: Migraine Headache
Interventions: Inhaled Placebo, Inhaled Loxapine 1.25 mg, Inhaled Loxapine 2.5 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 366 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 3
States / cities: Springfield, Missouri • Mount Vernon, New York • East Providence, Rhode Island

Conditions: Treatment of Induced Panic Attack
Interventions: Inhaled placebo, Inhaled alprazolam 1 mg, Inhaled alprazolam 2 mg, IV doxapram; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Brooklyn, New York • New York, New York

Conditions: Healthy Volunteers
Interventions: Lorazepam 1 mg IM, Inhaled loxapine 10 mg, Inhaled Placebo, Placebo IM; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 50 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: Healthy
Interventions: Inhaled Placebo, Inhaled Loxapine; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: North Dartmouth, Massachusetts

Conditions: Migraine
Interventions: Staccato Loxapine, Staccato Placebo; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Wellesley Hills, Massachusetts

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Inhaled Loxapine, Inhaled Placebo; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 40 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Spartanburg, South Carolina

Conditions: Migraine Headache, Aura
Interventions: Inhaled Placebo, Inhaled PCZ 5 mg, Inhaled PCZ 7.5 mg, Inhaled PCZ 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 70 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 25
States / cities: Scottsdale, Arizona • San Francisco, California • Santa Monica, California + 22 more

Conditions: Healthy
Interventions: 0.5mg AZ-010, 1mg AZ-010, 3mg AZ-010; Combination Product
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Bipolar I Disorder
Interventions: Inhaled Placebo, Inhaled loxapine 5 mg, Inhaled loxapine 10 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 6
States / cities: Escondido, California • Garden Grove, California • Atlanta, Georgia + 3 more

Conditions: Patients With Schizophrenia and Acute Agitation
Interventions: Inhaled loxapine 5 mg, Inhaled loxapine 10 mg, Inhaled placebo; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 344 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Healthy
Interventions: Inhaled placebo, Inhaled Zaleplon 0.5 mg, Inhaled Zaleplon 1 mg, Inhaled Zaleplon 2 mg, Inhaled Zaleplon 4 mg; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Evansville, Indiana

Conditions: Cardiotoxicity
Interventions: Inhaled placebo, Oral placebo, Inhaled prochlorperazine 5 mg, Inhaled prochlorperazine 10 mg, Oral moxifloxacin; Drug
Lead sponsor: Alexza Pharmaceuticals, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Evansville, Indiana

Search by objective public record fields.

Staccato Loxapine in Agitation (Proof of Concept)

Staccato Loxapine PK in Smokers and Nonsmokers

Staccato Fentanyl Single and Multidose PK

Observational Study Evaluating the Safety of ADASUVE® in Agitation Associated With Schizophrenia or Bipolar I Disorder

Staccato Prochlorperazine in Migraine (in Clinic)

Staccato Granisetron® (AZ 010) for the Treatment of Cyclic Vomiting Syndrome

Staccato Loxapine Pulmonary Safety in Patients With Asthma

Staccato Loxapine Multidose PK

Study to Evaluate the Efficacy and Safety of Staccato Apomorphine (AZ-009) in Patients With Parkinson's Disease Experiencing OFF Episodes

Staccato Loxapine Single Dose PK

Staccato Loxapine in Migraine (Out Patient)

Staccato Alprazolam in Panic Attack

ADASUVE-Lorazepam Drug-Drug Interaction

Staccato Loxapine Pulmonary Safety in Healthy Volunteers

Staccato Loxapine in Migraine (in Clinic)

Staccato Loxapine Pulmonary Safety in Patients With COPD

Staccato Prochlorperazine in Migraine (Out Patient)

Staccato® Granisetron Multiple Dose PK

Staccato Loxapine in Agitated Patients With Bipolar Disorder

Staccato Loxapine in Agitated Patients With Schizophrenia

Staccato Zaleplon Single Dose Pharmacokinetics

Staccato Prochlorperazine Thorough QT/QTc