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ClinicalTrials.gov public records Last synced Oct 4, 2026, 7:20 AM EDT

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Autism Speaks Clear all
Completed Phase 2 Interventional Results available

Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)

NCT01289912
View directory record Official record
Conditions
Tuberous Sclerosis Complex
Interventions
RAD001, Placebo
Drug
Lead sponsor
Mustafa Sahin
Other
Eligibility
6 Years to 21 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 4, 2026, 7:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Understanding Sleep Problems in Children With Autism Spectrum Disorder

NCT00691080
View directory record Official record
Conditions
Sleep Problems
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 9 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
3
States / cities
New York, New York • Portland, Oregon • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Parent-Child Interaction Therapy With Autism Spectrum Disorder

NCT02088905
View directory record Official record
Conditions
Noncompliance
Interventions
Parent Child Interaction Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Months to 83 Months
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 4, 2026, 7:20 AM EDT
Not listed Not applicable Interventional

Intestinal Inflammation and Carbohydrate Digestion in Autistic Children

NCT00227487
View directory record Official record
Conditions
Autism, Inflammation
Interventions
Stool collection, Administration of carbohydrate solution during clinically indicated endoscopy, Questionnaires
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Months to 17 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 2 Interventional Results available

Randomized Controlled Study of Donepezil in Fragile X Syndrome

NCT01120626
View directory record Official record
Conditions
Fragile X Syndrome
Interventions
donepezil, sugar pill
Drug
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 29 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 1 Interventional Results available

Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection)

NCT01253317
View directory record Official record
Conditions
Rett Syndrome
Interventions
rhIGF-1
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 12 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 1 Interventional

Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders

NCT00773812
View directory record Official record
Conditions
Autistic Disorder, Pervasive Developmental Disorder
Interventions
mecamylamine, placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
4 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 1 Interventional Results available

Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism

NCT02552147
View directory record Official record
Conditions
Autism Spectrum Disorder, Aggression, Irritability
Interventions
Transdermal nicotine, Transdermal placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 4, 2026, 7:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Relationships, Employment, Autonomy, and Life Satisfaction (REALS) Study

NCT04381195
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
REALS Development, REALS Testing
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acupressure and Acupuncture as an Intervention With Children With Autism II

NCT00935701
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Acupressure and Acupuncture
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
3 Years to 10 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 4, 2026, 7:20 AM EDT
Completed No phase listed Observational

Understanding Gastrointestinal Conditions in Children With Autism Spectrum Disorder (ASD)

NCT01675414
View directory record Official record
Conditions
Gastrointestinal Disorders, Autism Spectrum Disorders
Interventions
evaluation visit by a pediatric gastroenterologist
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 17 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 30, 2012 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 2 Interventional Results available

Omega-3 Fatty Acids for Autism Treatment

NCT00786799
View directory record Official record
Conditions
Autism
Interventions
Omega-3 Fatty Acids
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
3 Years to 8 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2012 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 3 Interventional

Study of Fluoxetine in Autism

NCT00515320
View directory record Official record
Conditions
Autistic Disorder
Interventions
Fluoxetine, Placebo
Drug
Lead sponsor
Neuropharm
Industry
Eligibility
5 Years to 17 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
17
States / cities
Phoenix, Arizona • Sacramento, California • Gainesville, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2012 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional

Structured Function-Based Elopement Treatment Program

NCT03899831
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Function-Based Elopement Treatment (FBET), Parent Education Program (PEP)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
4 Years to 12 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional

Optimizing Social and Communication Outcomes for Toddlers With Autism

NCT00999778
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Caregiver-Mediated Intervention, Caregiver-Education Intervention
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Months to 36 Months
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional Results available

Providing Accessible Diagnostic Evaluations and Psychoeducation for Autism Spectrum Disorder in Rural Southwest Virginia

NCT05822921
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
In-person Psychoeducation (IP), Telehealth Psychoeducation (TH), Psychoeducation as Usual (PAU)
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
16 Months to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Blacksburg, Virginia • Wytheville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Early Phase 1 Interventional Results available

Probiotics for Quality of Life in Autism Spectrum Disorders

NCT02903030
View directory record Official record
Conditions
Autism Spectrum Disorders, Anxiety
Interventions
Maltose (placebo), Visbiome Extra Strength
Drug
Lead sponsor
Ohio State University
Other
Eligibility
3 Years to 12 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 4, 2026, 7:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Caregiver Skills Training: Comparing Clinician Training Methods

NCT06038799
View directory record Official record
Conditions
Parenting
Interventions
Caregiver Skills Training (CST)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Altoona, Pennsylvania • McKeesport, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 4, 2026, 7:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Manualized Assessment and Treatment Model of Challenging Behavior

NCT05928247
View directory record Official record
Conditions
Problem Behavior, Aggression, Self-Injury
Interventions
Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking, Research Units in Behavioral Intervention (RUBI) protocol
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 4, 2026, 7:20 AM EDT
Recruiting Phase 2 Interventional

Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism

NCT04060030
View directory record Official record
Conditions
Autism Spectrum Disorder, Language Disorders
Interventions
Levoleucovorin Calcium, Placebo
Drug · Other
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
30 Months to 60 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional

Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

NCT00902798
View directory record Official record
Conditions
Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 45 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Connections, Early Detection and Intervention in Infants at Risk for Autism

NCT00947700
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Assessment, Monitoring & Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
5 Months to 12 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Phase 3 Interventional Results available

Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders

NCT01302964
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Placebo, Mirtazapine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
2
States / cities
Indianapolis, Indiana • Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Oct 4, 2026, 7:20 AM EDT
Completed Not applicable Interventional Results available

Pivotal Response Group Treatment for Parents of Young Children With Autism

NCT01881750
View directory record Official record
Conditions
Autistic Disorder
Interventions
Pivotal Response Training (PRT), Parent Education Group (PEG)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 6 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2019 · Synced Oct 4, 2026, 7:20 AM EDT