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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Axogen Corporation Clear all
Completed No phase listed Observational

Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy

NCT03909464
View directory record Official record
Conditions
Cancer, Malignancy, Malignant Neoplasm, Neuropathy, Neuropathies Sensory, Chemotherapy-induced Peripheral Neuropathy
Interventions
Neurosensory testing with Pressure-Specified Sensory Device
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Sep 29, 2026, 8:38 AM EDT
Recruiting Phase 4 Interventional

A Prospective, Randomized, Assessor-Blinded, Multicenter Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction

NCT07657182
View directory record Official record
Conditions
Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury, Upper Extremity Nerve Injury
Interventions
Avance Nerve Graft, Sural nerve autograft
Biological · Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 29, 2026, 8:38 AM EDT
Terminated Not applicable Interventional

Sensory Restoration After DIEP Flap Neurotization

NCT04533373
View directory record Official record
Conditions
Breast Cancer, Breast Reconstruction, Sensory Restoration
Interventions
DIEP Flap Neurotization
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 29, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain

NCT03940963
View directory record Official record
Conditions
Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
Interventions
AxoGuard® Nerve Cap, Standard Neurectomy
Device · Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
11
States / cities
Los Angeles, California • Saint Augustine, Florida • Roswell, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 29, 2026, 8:38 AM EDT
Active, not recruiting No phase listed Observational

Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction

NCT01526681
View directory record Official record
Conditions
Peripheral Nerve Injuries
Interventions
Processed Human Nerve Graft, Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc., Autogenous Nerve Graft, Nerve Tube Conduit, Autologous Breast Reconstruction with Neurotization, Autologous Breast Reconstruction without Neurotization
Other · Device · Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
Not listed
Enrollment
3,126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2028
U.S. locations
46
States / cities
Phoenix, Arizona • Orange, California • San Francisco, California + 33 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 29, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

Axoguard HA Plus Nerve Protector to Reduce Post-operative Neck and Shoulder Dysfunction in Patients Undergoing Neck Dissection

NCT07283861
View directory record Official record
Conditions
Head and Neck Cancer, Neck Dissection
Interventions
Spinal Accessory Nerve Protection utilizing Axoguard HA+
Device
Lead sponsor
Matthew Spector
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 29, 2026, 8:38 AM EDT
Terminated No phase listed Observational

Registry of Avive® Soft Tissue Membrane Utilization in Selected Applications of Acute Trauma of the Upper Extremity

NCT03943134
View directory record Official record
Conditions
Acute Upper Extremity Trauma
Interventions
Minimally Processed Human Umbilical Cord Membrane, Standard Surgical Procedures
Other
Lead sponsor
Axogen Corporation
Industry
Eligibility
5 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Tampa, Florida • Indianapolis, Indiana • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 29, 2026, 8:38 AM EDT
Completed Phase 4 Interventional

Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer

NCT00953277
View directory record Official record
Conditions
Peripheral Nerve Injury, Prostate Cancer, Radical Prostatectomy, Nerve Reconstruction, Cavernous Nerve Injury
Interventions
Processed Human Nerve Tissue Scaffold
Other
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years to 70 Years · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 29, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression

NCT06117501
View directory record Official record
Conditions
Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Interventions
Axoguard HA+ Nerve Protector™
Device
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Tampa, Florida • Savannah, Georgia • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 29, 2026, 8:38 AM EDT
Terminated No phase listed Observational

Surgical Treatment of Chronic Neuropathic Pain

NCT04287075
View directory record Official record
Conditions
Chronic Neuropathic Pain
Interventions
Surgical Management of Neuroma
Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Tampa, Florida • Indianapolis, Indiana • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 29, 2026, 8:38 AM EDT
Terminated Not applicable Interventional Results available

A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options

NCT00948025
View directory record Official record
Conditions
Traumatic Nerve Injury
Interventions
Hollow tube nerve conduit, synthetic or biosynthetic, Processed Human Nerve Tissue
Device · Other
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
4
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Lexington, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2020 · Synced Sep 29, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

NCT04865679
View directory record Official record
Conditions
Symptomatic Neuroma, Amputation, Chronic Nerve Pain
Interventions
Axoguard Nerve Cap®
Device
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 29, 2026, 8:38 AM EDT
Completed Phase 3 Interventional Results available

Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair

NCT01809002
View directory record Official record
Conditions
Peripheral Nerve Discontinuities
Interventions
Processed Nerve Allograft (human), Collagen Nerve Cuff
Biological · Device
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
21
States / cities
Sacramento, California • Gainesville, Florida • Miami, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Sep 29, 2026, 8:38 AM EDT