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ClinicalTrials.gov public records Last synced Oct 5, 2026, 9:29 AM EDT

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Showing 1–24 of 842 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Boston Children's Hospital Clear all
Enrolling by invitation Not applicable Interventional

ESG in Obese Adolescents

NCT06914765
View directory record Official record
Conditions
Obese Adolescents, Obesity, Morbid, Obesity/Therapy
Interventions
Endoscopic Sleeve Gastroplasty (ESG) Procedure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 5, 2026, 9:29 AM EDT
Completed No phase listed Observational

Modifiers of Disease Severity in Cerebral Cavernous Malformations

NCT01764529
View directory record Official record
Conditions
Cavernous Angioma, Familial, Cerebral Cavernous Malformations, Cerebral Cavernous Hemangioma
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
789 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2025
U.S. locations
7
States / cities
Phoenix, Arizona • San Francisco, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Skeletal Health and Bone Marrow Composition Among Youth

NCT04203381
View directory record Official record
Conditions
Gender Dysphoria in Children, Puberty, Bone Development
Interventions
GnRH Agonist
Device
Lead sponsor
Amy DiVasta, MD
Other
Eligibility
9 Years to 14 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Enrolling by invitation Not applicable Interventional

Assessing Post-operative Outcomes After Children's Sistrunk Procedure With or Without a Drain

NCT07148895
View directory record Official record
Conditions
Thyroglossal Duct Cysts
Interventions
Post-surgical drain, No post-surgical drain
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
3 Years to 17 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Los Angeles, California • Hartford, Connecticut • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive Therapy

NCT00727636
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Gardasil vaccine
Biological
Lead sponsor
Boston Children's Hospital
Other
Eligibility
9 Years to 26 Years · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 27, 2011 · Synced Oct 5, 2026, 9:29 AM EDT
Completed No phase listed Observational

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

NCT04967365
View directory record Official record
Conditions
Critical Illness, Post Intensive Care Unit Syndrome
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Month to 16 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
30
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Active, not recruiting No phase listed Observational

Use of Intrapyloric Botulinum Injections in Children

NCT04250844
View directory record Official record
Conditions
Vomiting, Feeding Disorders, Gastroparesis
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
30 Days to 18 Years
Enrollment
100 participants
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Not yet recruiting Phase 1 Interventional

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

NCT03653702
View directory record Official record
Conditions
Vesico-Ureteral Reflux
Interventions
Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Months to 35 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Withdrawn Phase 2 Interventional

Treatment of Children With Autism Spectrum Disorders and Epileptiform EEG With Divalproex Sodium

NCT02094651
View directory record Official record
Conditions
Autism
Interventions
divalproex sodium, Placebo
Drug · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 10 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Louisville, Kentucky • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 5, 2026, 9:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analytic, Prospective Cohort Study of Athletes Enrolled in an Exercise Training Intervention

NCT02999139
View directory record Official record
Conditions
Exercise Training
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years and older
Enrollment
633 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 5, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot

NCT05236153
View directory record Official record
Conditions
Tetralogy of Fallot, Ventricular Tachycardia, Sudden Cardiac Death
Interventions
Electroanatomic substrate mapping
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 5, 2026, 9:29 AM EDT
Completed No phase listed Observational

Protease Activated Receptor-2 and Gastrointestinal Dysfunction in Critical Illness

NCT03011151
View directory record Official record
Conditions
Gastroparesis, Gastrointestinal Disorder, Functional, Critical Illness
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 30 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Recruiting No phase listed Observational

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

NCT06585605
View directory record Official record
Conditions
Epilepsy in Children, Dyskinesias, Movement Disorders in Children, Neurologic Disorder, Chorea, Myoclonus, Ataxia, Epilepsy, Dystonia Disorder, Movement Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 18 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Primary Connections for Youth and Families

NCT05964010
View directory record Official record
Conditions
Substance Use
Interventions
Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 17 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Active, not recruiting Not applicable Interventional

Sonographic Assessment of Cricoid Pressure

NCT04190524
View directory record Official record
Conditions
Aspiration; Gastric Contents, Anesthesia, Intubation Complication
Interventions
Application of cricoid pressure, Application of Left lateral paratracheal pressure
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Not applicable Interventional

Postoperative Pain After Pediatric Umbilical Hernia Repair

NCT01015053
View directory record Official record
Conditions
Pediatric Postoperative Pain
Interventions
bilateral ultrasound-guided rectus sheath block, Wound infiltration
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 12 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 5, 2026, 9:29 AM EDT
Recruiting Not applicable Interventional

Striae Distensae Treatment Using Deep Skin Abrasion

NCT07087405
View directory record Official record
Conditions
Striae Distensae
Interventions
Striae Distensae Treatment Device
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 5, 2026, 9:29 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Doxorubicin Pharmacokinetic (PK) Study

NCT00124956
View directory record Official record
Conditions
Cancer
Interventions
Doxorubicin
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Year to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 5, 2026, 9:29 AM EDT
Recruiting No phase listed Observational

Identifying Genetic Causes of IC/BPS

NCT00389142
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Year and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

Dietary Glycemic Index, Brain Function and Food Intake in Patients With Type 1 Diabetes Mellitus

NCT02772783
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
high GI meal, low GI meal, euglycemic insulin clamp, primed-variable insulin infusion
Other · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Phase 2 Interventional Results available

Treatment of Rett Syndrome With Recombinant Human IGF-1

NCT01777542
View directory record Official record
Conditions
Rett Syndrome
Interventions
Recombinant Human Insulin Growth Factor 1 (rhIGF-1), Placebo
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 10 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Oct 5, 2026, 9:29 AM EDT
Completed No phase listed Observational

The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Disease

NCT03912025
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Relationship between positive mindset and exercise capacity
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
90 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 5, 2026, 9:29 AM EDT
Completed Phase 3 Interventional

Treatment of Acute Lymphoblastic Leukemia in Children

NCT00165178
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
prednisone, dexamethasone, doxorubicin, E. coli asparaginase, vincristine, methotrexate, Leucovorin, Asparaginase, cytarabine, Methotrexate/Hydrocortisone
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
1 Year to 18 Years
Enrollment
498 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Oct 5, 2026, 9:29 AM EDT