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ClinicalTrials.gov public records Last synced Oct 8, 2026, 1:40 AM EDT

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Showing 1–24 of 1,661 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Brigham and Women's Hospital Clear all
Completed Phase 3 Interventional Results available

9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis

NCT04510220
View directory record Official record
Conditions
Relapsing Multiple Sclerosis
Interventions
Ofatumumab, [F-18]PBR06
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 8, 2026, 1:40 AM EDT
Terminated Phase 4 Interventional Results available

Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma

NCT01070888
View directory record Official record
Conditions
Exercise Induced Asthma
Interventions
Budesonide/Formoterol, Budesonide
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 8, 2026, 1:40 AM EDT
Completed No phase listed Observational

Replication of the POET-COPD Trial in Healthcare Claims Data

NCT05083429
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Salmeterol, Tiotropium
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 120 Years
Enrollment
8,716 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 8, 2026, 1:40 AM EDT
Not listed Phase 1Phase 2 Interventional

Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy

NCT05550246
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Atomoxetine, Oxybutynin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 8, 2026, 1:40 AM EDT
Recruiting Not applicable Interventional

Trans-nasal Endoscopy for Bariatric Patients

NCT06200961
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obese, GI Disorders, Gastrointestinal Diseases
Interventions
Transnasal Endoscopy, Esophagogastroduodenoscopy
Device · Procedure
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 1 Interventional

Impact of Fecal Biotherapy (FBT) on Microbial Diversity in Patients With Moderate to Severe Inflammatory Bowel Disease

NCT01847170
View directory record Official record
Conditions
Crohn's Disease
Interventions
Fecal Microbial Transplantation
Biological
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Not applicable Interventional Results available

Somatostatin Receptor Imaging in Patients With Suspected Cardiac Sarcoidosis

NCT02546388
View directory record Official record
Conditions
Sarcoidosis
Interventions
Indium-111 Pentreotide, Gallium-68 DOTATATE
Drug
Lead sponsor
Marcelo F. Di Carli, MD, FACC
Other
Eligibility
18 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Oct 8, 2026, 1:40 AM EDT
Completed No phase listed Observational

Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction

NCT06914141
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, HFpEF - Heart Failure With Preserved Ejection Fraction
Interventions
Tirzepatide, Semaglutide
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
28,118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 2 Interventional Results available

Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors

NCT00520013
View directory record Official record
Conditions
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Papillary Serous Mullerian Tumor, Clear Cell Mullerian Tumor
Interventions
bevacizumab, erlotinib, paclitaxel, carboplatin
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2018 · Synced Oct 8, 2026, 1:40 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families

NCT06020027
View directory record Official record
Conditions
Water, Child Nutrition, Family Dynamics, Healthy Nutrition, Healthy Lifestyle, Health-Related Behavior, Obesity Prevention
Interventions
Water is K'é
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
2 Years and older
Enrollment
1,160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Window Rock, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 1 Interventional

C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and Neck

NCT00402545
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
Cetuximab, Docetaxel, Cisplatin, 5-Fluorouracil
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 2, 2009 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Not applicable Interventional

Medically Used Tailored Traditional Food to Optimize Nutrition in Heart Failure

NCT06549699
View directory record Official record
Conditions
Heart Failure
Interventions
Medically Tailored Meal Program with Traditional Navajo Foods, Usual Care
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Gallup, New Mexico • Tohatchi, New Mexico
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 8, 2026, 1:40 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Investigation of a Patient Support Intervention for Statin Medication Adherence

NCT06972979
View directory record Official record
Conditions
Medication Adherence
Interventions
Text Message Gamification and Remote Support
Behavioral
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 3 Interventional

Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease

NCT00939237
View directory record Official record
Conditions
Coronary Heart Disease
Interventions
Ateronon, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Not applicable Interventional Results available

NUDGE-EHR Replication Trial at Mass General Brigham

NCT05538065
View directory record Official record
Conditions
Aging, Benzodiazepine Sedative Adverse Reaction, Anticholinergic Adverse Reaction, Adverse Drug Event
Interventions
Follow-up booster Alert, Pre-commitment, Enhanced Alert
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 2 Interventional

Preoperative Cisplatin in Early Stage Breast Cancer

NCT00148694
View directory record Official record
Conditions
Breast Cancer
Interventions
Cisplatin
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2016 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 1Phase 2 Interventional

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

NCT03892772
View directory record Official record
Conditions
Sleep Apnea
Interventions
SAS0421a, SAS0421b, SAS0421c, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 3 Interventional

Integrated Treatment Program for Hypochondriasis in Primary Care Settings

NCT00368212
View directory record Official record
Conditions
Hypochondriasis, Somatoform Disorders
Interventions
Relaxation response training, Psychoeducational counseling
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Not applicable Interventional

Improving Safety of Diagnosis and Therapy in the Inpatient Setting

NCT04393909
View directory record Official record
Conditions
Delirium, Confusion, Mental Status Change, Back Pain, Hip Pain Chronic, Chest Pain, Asthma, COPD, Cellulitis, Soft Tissue Infections, Cough, Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Dyspnea, Electrolyte Metabolism Abnormal, Fever, Failure to Thrive, Weakness, Protein-Calorie Malnutrition, Headache, Neck Pain, Hypoxia, Pneumonia, Sepsis, Syncope, Vomiting, Diarrhea, Leg Pain, Abdominal Pain
Interventions
Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire, Enhancements to Epic-integrated Quality & Safety Dashboard
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 8, 2026, 1:40 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

COMT on Aspirin Platelets Effects (CAPE)

NCT03433586
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Aspirin 81 mg, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2021 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Phase 4 Interventional Results available

Targeting Cognition in Bipolar Disorder With Pramipexole

NCT02397837
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Pramipexole, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
Boston, Massachusetts • Glen Oaks, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 8, 2026, 1:40 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Functional Neuroimaging of Cortical Plasticity in the Human Visual System

NCT01062672
View directory record Official record
Conditions
Stroke, Blindness, Vision
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Oct 8, 2026, 1:40 AM EDT
Completed Not applicable Interventional

Short-Term Endogenous Hydrogen Sulfide Upregulation

NCT03303534
View directory record Official record
Conditions
Carotid Stenosis, Caloric Restriction
Interventions
ScandiShake
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 8, 2026, 1:40 AM EDT
Recruiting Not applicable Interventional

Pictographs for Preventing Wrong-Patient Errors in NICUs

NCT03960099
View directory record Official record
Conditions
Medical Errors, Electronic Medical Records
Interventions
Pictograph in Banner and Verification Alert
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 8, 2026, 1:40 AM EDT