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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Cambridge Health Alliance Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effectiveness and Acceptability of Formal Versus Informal Mindful Self-Compassion for Adolescents

NCT07513220
View directory record Official record
Conditions
Coping
Interventions
Formal Mindful Self-Compassion (MSC-F), Informal Mindful Self-Compassion (MSC-I)
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
14 Years to 19 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Malden, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Double-Blind, Placebo-Controlled Study of Galantamine to Improve Cognitive Dysfunction in Bipolar Disorder

NCT00195845
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Galantamine, Placebos
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 1, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

NCT04697966
View directory record Official record
Conditions
Rumination
Interventions
Mindfulness (Headspace) App, Active Control Condition ("Recharge" condition delivered in Headspace app)
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional

MySafeRx & MedicaSafe Open-Label Buprenorphine Induction and Lapse Evaluation (MyMOBILE)

NCT02942199
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
MySafeRx
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 39 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Results available

Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 2)

NCT03265600
View directory record Official record
Conditions
Depression, Anxiety, Stress Related Disorder, Adjustment Disorders
Interventions
Mindfulness Training for Primary Care, 60-minute Introduction to Mindfulness
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Adaptive Dispenser Initiation Protocols for MySafeRx During Post-detox Buprenorphine Treatment- a Pilot Study

NCT04449744
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
MySafeRx Inspire Plus, MySafeRx Inspire Flex
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Evaluating Sequential Strategies to Reduce Readmission in a Diverse Population

NCT01619098
View directory record Official record
Conditions
Hospital Readmission, Post-discharge Care Transitions, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Interventions
Patient Navigator, Usual care
Other
Lead sponsor
Alison Galbraith
Other
Eligibility
18 Years and older
Enrollment
1,510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Cambridge, Massachusetts • Everett, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2014 · Synced Sep 1, 2026, 2:11 PM EDT
Completed No phase listed Observational

Exploring a Potential Blood Test to Diagnose Major Depressive Disorder

NCT00705185
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
5
States / cities
Farmington, Connecticut • Chicago, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2010 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Hospital-to-Home Care Transitions for High-risk Younger Adult Patients

NCT02532296
View directory record Official record
Conditions
Patient Discharge
Interventions
Transition Coach (TC), Control
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 60 Years
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2016 · Synced Sep 1, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional

Improving Mental Health Treatment for Individuals in Crisis Interacting With the Criminal-Legal System

NCT06564948
View directory record Official record
Conditions
Suicide Risk, Psychiatric Disorders
Interventions
Treatment as usual (TAU), FSJS, FSJS+Navigator Intervention
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 100 Years
Enrollment
1,040 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 1, 2026, 2:11 PM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Patients' Attitudes Toward and Experiences With Buprenorphine Treatment

NCT05121428
View directory record Official record
Conditions
Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
Interventions
Not listed
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Heart-Smile Training Intensive Introduction Program

NCT05564533
View directory record Official record
Conditions
Depression
Interventions
Heart-Smile Training Intensive Introduction Program (HST-IIP)
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease

NCT04419025
View directory record Official record
Conditions
COVID, Sars-CoV2, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
Interventions
N-acetylcysteine
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
4
States / cities
Cambridge, Massachusetts • Everett, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional

MINDFUL-PC: Integrating Mindfulness Into the Patient-Centered Medical Home

NCT02972203
View directory record Official record
Conditions
Depression, Anxiety, Stress Related Disorder, Adjustment Disorder
Interventions
Mindfulness Training for Primary Care, Mindfulness Intro. +resources +waitlist
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of RME on Engagement in Buprenorphine Treatment

NCT05184907
View directory record Official record
Conditions
Opioid Use Disorder, Behavioral Symptoms, Psychiatric or Mood Diseases or Conditions
Interventions
Remote Motivational Enhancement (RME) Intervention Arm, Information Only
Behavioral · Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Phase 4 Interventional

An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.

NCT00391261
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar Disorder, Autism Spectrum Disorders
Interventions
Metformin
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
10 Years to 18 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Sep 1, 2026, 2:11 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

NAC for Attenuation of COVID-19 Symptomatology

NCT05074121
View directory record Official record
Conditions
Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
Interventions
N-acetylcysteine, Placebo
Drug · Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Everett, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Phase 4 Interventional

Ropinirole in the Treatment of Bipolar Depression

NCT00314821
View directory record Official record
Conditions
Bipolar Disorder
Interventions
ropinirole
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 64 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Atlanta, Georgia • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 1, 2026, 2:11 PM EDT
Active, not recruiting Not applicable Interventional

Skilled Nursing Facility Care at Home

NCT06416670
View directory record Official record
Conditions
Skilled Nursing Facility, Rehabilitation
Interventions
Skilled nursing facility care at home
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
5
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 1, 2026, 2:11 PM EDT
Terminated Phase 1 Interventional

Taurine in Adolescents With Bipolar Disorder

NCT00391001
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Taurine
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
13 Years to 18 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
2
States / cities
Belmont, Massachusetts • Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2010 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention and Early Identification for High Risk Youth in School-based Clinics

NCT04935710
View directory record Official record
Conditions
Community Mental Health Services, Adolescent Well Being, Resilience, Psychological, Health Equity, Screening
Interventions
COPE2Thrive, Usual care
Behavioral · Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
12 Years to 24 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
5
States / cities
Cambridge, Massachusetts • Everett, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Phase 2 Interventional Results available

An Open-Label Trial of Aripiprazole in Autism Spectrum Disorders

NCT00308074
View directory record Official record
Conditions
Autism, Asperger's Disorder, Pervasive Developmental Disorder
Interventions
Aripiprazole
Drug
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
6 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Medford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Sep 1, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional

Family Connections

NCT06662357
View directory record Official record
Conditions
Emotional Disturbance, Behavior Disorders in Children
Interventions
Behavioral Treatment
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
3 Years to 18 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 1, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Program for Alleviating and Resolving Trauma and Stress 2

NCT05095428
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
PARTS Program, NBSR-T Program
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 75 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 1, 2026, 2:11 PM EDT