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ClinicalTrials.gov public records Last synced Oct 5, 2026, 12:47 PM EDT

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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: DeNova Research Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation

NCT02726451
View directory record Official record
Conditions
Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions
Basic Skin Care, Active Skin Care
Other
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

First Impressions and Attractiveness Levels of Smiling Individuals With and Without a Mask

NCT05343559
View directory record Official record
Conditions
First Impressions, Attractiveness
Interventions
Not listed
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 39 Years
Enrollment
808 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 5, 2026, 12:47 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oral Nutraceutical Supplement With Standardized Botanicals in Males With Self-Perceived Thinning Hair and Loss

NCT03709563
View directory record Official record
Conditions
Hair Loss, Hair Thinning
Interventions
Oral Nutraceutical Supplement, Placebo
Dietary Supplement
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 45 Years · Male only
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty

NCT04169308
View directory record Official record
Conditions
Deformity of Nasal Cartilage
Interventions
Restylane-L® Filler injection
Drug
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite

NCT04677712
View directory record Official record
Conditions
Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite
Interventions
CCH-aaes, Compression, Cold Packs, Arnica Gel, INhance®, PDL
Drug · Other
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
8
States / cities
Scottsdale, Arizona • Sacramento, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures

NCT01919359
View directory record Official record
Conditions
Ecchymosis and Erythema Commonly Associated With Soft Tissue Filler Injections
Interventions
Multizyme Cellular Vitality Cyruta Plus SHEP
Dietary Supplement
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 5, 2026, 12:47 PM EDT
Terminated Not applicable Interventional Results available

Botulinum Toxin A for Herpes Labialis

NCT01225341
View directory record Official record
Conditions
Herpes Labialis
Interventions
onabotulinumtoxinA, Bacteriostatic normal saline
Drug · Other
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 2 Interventional Results available

A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty

NCT01684020
View directory record Official record
Conditions
Subjects Requesting and Requiring an Open Rhinoplasty
Interventions
ARTISS human fibrin sealant
Biological
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Efficacy of the Use of Botox on Acne

NCT00765375
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Botulinum Neurotoxin Type A, Bacteriostatic saline
Drug
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 4 Interventional Results available

Injectable Filler for Cheek Flattening

NCT01225354
View directory record Official record
Conditions
Malar Deficiency
Interventions
Calcium hydroxylapatite
Drug
Lead sponsor
DeNova Research
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Surgical Rhinoplasty Using PDO Threads

NCT04769427
View directory record Official record
Conditions
Nasal Defect
Interventions
PDO max threads
Device
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Restylane® Lyft Filler Injection for Hand Rejuvenation on First Impressions

NCT04162002
View directory record Official record
Conditions
Hand Rejuvination
Interventions
Restylane® Lyft
Drug
Lead sponsor
DeNova Research
Other
Eligibility
28 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments

NCT02551562
View directory record Official record
Conditions
Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions
NuDerm® System, Placebo
Other
Lead sponsor
DeNova Research
Other
Eligibility
25 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction

NCT04439825
View directory record Official record
Conditions
Mood
Interventions
Botulinum Neurotoxin, Placebo
Drug
Lead sponsor
DeNova Research
Other
Eligibility
10 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Ethnic Lip Augmentation With Hyaluronic Acid Filler

NCT05730543
View directory record Official record
Conditions
Lip Augmentation, Lip Fullness
Interventions
Volbella or Juvederm Ultra XC filler
Drug
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Controlled Study on Pain Management With Injection of Botulinum Toxin for Glabellar Line Correction

NCT06161246
View directory record Official record
Conditions
Injection Site Discomfort
Interventions
Vibrating Beauty Bar
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions

NCT03241862
View directory record Official record
Conditions
Lip Rejuvenation
Interventions
Restylane® Silk
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Phase 2 Interventional Results available

A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of IncobotulinumtoxinA Versus Saline Injections to the Cheek Region in Patients With Rosacea

NCT01614743
View directory record Official record
Conditions
Rosacea
Interventions
IncobotulinumtoxinA, Bacteriostatic saline
Drug
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty

NCT01225250
View directory record Official record
Conditions
Rhinoplasty
Interventions
Polydioxanone (PDS) plates, Caudal septal extension graft performed through endonasal rhinoplasty
Device · Procedure
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 5, 2026, 12:47 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

ZOOM First Impressions

NCT05739721
View directory record Official record
Conditions
Attractiveness, Self Esteem, First Impressions
Interventions
Attractiveness, Self-Esteem, Trustworthiness
Behavioral
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 39 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 5, 2026, 12:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Perioral Rejuvenation and Upper Lip Enhancement

NCT03273543
View directory record Official record
Conditions
Perioral Rejuvenation, Upper Lip Projection
Interventions
Restylane® Defyne
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 5, 2026, 12:47 PM EDT