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ClinicalTrials.gov public records Last synced Oct 1, 2026, 2:06 AM EDT

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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: DePuy Spine Clear all
Completed No phase listed Observational

Cost Effectiveness of Nonoperative Management for Adult Spinal Deformity

NCT01880164
View directory record Official record
Conditions
Spinal Deformity
Interventions
Not listed
Lead sponsor
Shay Bess
Other
Eligibility
40 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
10
States / cities
Sacramento, California • San Francisco, California • Denver, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Oct 1, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc Degeneration

NCT01124006
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5, Water for injection
Drug · Other
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
10
States / cities
Phoenix, Arizona • Santa Monica, California • Durango, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational

Prospective Study of Motion Preservation Evaluation Below Fusions of the Spine in Adolescent Idiopathic Scoliosis

NCT01661998
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
8 Years to 21 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
3
States / cities
San Diego, California • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational

CHARITE™ vs. ALIF 5-Year Follow-up

NCT00215332
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
CHARITE
Device
Lead sponsor
DePuy Spine
Industry
Eligibility
Not listed
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
10
States / cities
Los Angeles, California • Golden, Colorado • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Oct 1, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)

NCT00432159
View directory record Official record
Conditions
Cervical Degenerative Disc Disease
Interventions
Cervical TDR, ACDF with plate
Device
Lead sponsor
DePuy Spine
Industry
Eligibility
21 Years to 70 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
30
States / cities
Beverly Hills, California • Sacramento, California • Loveland, Colorado + 26 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2017 · Synced Oct 1, 2026, 2:06 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Healos as a Bone Replacement to Treat Degenerative Disc Disease

NCT00316121
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
HEALOS and Leopard Cage, Leopard Cage and Autograft
Device
Lead sponsor
Advanced Technologies and Regenerative Medicine, LLC (ATRM)
Other
Eligibility
18 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
17
States / cities
Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2011 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational

Prospective Study of Scheuermann's Kyphosis

NCT00738309
View directory record Official record
Conditions
Scheuermann's Kyphosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
Up to 21 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
8
States / cities
Sacramento, California • San Diego, California • Wilmington, Delaware + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 1, 2026, 2:06 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Intradiscal rhGDF-5 Phase I/II Clinical Trial

NCT00813813
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5
Drug
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
8
States / cities
Santa Monica, California • Durango, Colorado • Marietta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2016 · Synced Oct 1, 2026, 2:06 AM EDT
Active, not recruiting No phase listed Observational

Evaluation of Symphony™ Posterior Cervical System for Surgical Treatment of Adult Cervical Deformity

NCT04912674
View directory record Official record
Conditions
Cervical Deformity
Interventions
Symphony OCT System
Device
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Sacramento, California • Denver, Colorado • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational

Prospective Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity

NCT01588054
View directory record Official record
Conditions
Cervical Deformity, Kyphosis, Scoliosis
Interventions
Not listed
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
10
States / cities
La Jolla, California • Sacramento, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 1, 2026, 2:06 AM EDT
Completed Phase 3 Interventional

Titanium Surgical Mesh and MOSS-Miami Screws for Lumbar Fusion.

NCT00215319
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Lumbar I/F with cage and pedicle screws
Device
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years to 79 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
2
States / cities
Dothan, Alabama • Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated May 23, 2014 · Synced Oct 1, 2026, 2:06 AM EDT
Not listed No phase listed Observational

Adolescent Idiopathic Scoliosis Outcomes Database Registry

NCT01661959
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
10 Years to 21 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2025
U.S. locations
12
States / cities
San Diego, California • Wilmington, Delaware • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Clinical Evaluation of the New Aegis Plate for Anterior Interbody Fusions

NCT00555659
View directory record Official record
Conditions
Degeneration, Spondylosis, Spondylolithesis, Stenosis
Interventions
Not listed
Lead sponsor
Columbia Orthopaedic Group, LLP
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Oct 1, 2026, 2:06 AM EDT
Recruiting No phase listed Observational

Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

NCT04194996
View directory record Official record
Conditions
Cervical Deformity
Interventions
Surgical intervention
Procedure
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
16
States / cities
La Jolla, California • Sacramento, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 1, 2026, 2:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gait and Postural Stability Assessment in Children With Idiopathic Scoliosis Undergoing Posterior Spine Instrumentation

NCT01109082
View directory record Official record
Conditions
Scoliosis
Interventions
posterior spine fusion
Procedure
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
1 Year to 20 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 1, 2026, 2:06 AM EDT