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ClinicalTrials.gov public records Last synced Oct 9, 2026, 2:47 AM EDT

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Showing 1–24 of 114 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: East Carolina University Clear all
Terminated Not applicable Interventional Results available

Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon

NCT03951064
View directory record Official record
Conditions
Obesity, Morbid, Ventilator-Induced Lung Injury, Respiratory Failure
Interventions
Esophageal balloon, Intervention Spontaneous Breathing Trial (SBT) and Extubation, Control Spontaneous Breathing Trial and Extubation, Intervention Weaning after Tracheostomy, Control Weaning after Tracheostomy
Device · Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Phase 4 Interventional

Young Hearts, Strong Starts

NCT01893593
View directory record Official record
Conditions
Cardiovascular Risk Reduction
Interventions
Intervention, Control
Other
Lead sponsor
RTI International
Other
Eligibility
3 Years to 11 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Chicago, Illinois • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2014 · Synced Oct 9, 2026, 2:47 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Baylor Infant and Toddler Biomarker of Nutrition Study

NCT05869760
View directory record Official record
Conditions
Healthy Nutrition, Healthy Diet
Interventions
Carotenoid Intake, Serum carotenoid concentrations
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Months to 24 Months
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 9, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MAMA Tot - Healthy Weight Parallel Study

NCT06598098
View directory record Official record
Conditions
Pregnancy Related
Interventions
Exercise Modes
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 9, 2026, 2:47 AM EDT
Terminated Phase 4 Interventional

Combinatorial Therapy for Peristent Type 2 Diabetes After Gastric Banding

NCT01597531
View directory record Official record
Conditions
Type 2 Diabetes, Gastric Banding
Interventions
Liraglutide, Orlistat, Liraglutide + Orlistat
Drug
Lead sponsor
East Carolina University
Other
Eligibility
25 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity Following Surgery Induced Weight Loss

NCT00692367
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 60 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
2
States / cities
Greenville, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 4, 2014 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Phase 1Phase 2 Interventional

Pramipexole and Morphine for Renal Colic

NCT04160520
View directory record Official record
Conditions
Renal Colic
Interventions
Pramipexole, Morphine, Placebo oral tablet
Drug
Lead sponsor
East Carolina University
Other
Eligibility
19 Years to 66 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Oct 9, 2026, 2:47 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Comparing Site-selection Strategies

NCT03870217
View directory record Official record
Conditions
Deafness
Interventions
Site selection
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
15 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 9, 2026, 2:47 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Postural Control During Concurrent Cognitive Tasks During Optic Flow Stimulation

NCT05117463
View directory record Official record
Conditions
Aging, Postural Balance
Interventions
Optic Flow Stimulation, Auditory Reaction Time
Other
Lead sponsor
Chia-Cheng Lin, PhD, PT, MSPT
Other
Eligibility
25 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Phase 2 Interventional

Medically Reproducing Bariatric Surgery

NCT03225209
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
OPTIFAST
Other
Lead sponsor
Moahad S Dar
Other
Eligibility
25 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 9, 2026, 2:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Relationships Among Sedentary Behaviors and Other Factors

NCT04039438
View directory record Official record
Conditions
Older Adults
Interventions
No intervention
Other
Lead sponsor
East Carolina University
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Phase 2 Interventional

Trial of Naltrexone and Dextromethorphan for Gulf War Illness

NCT02206490
View directory record Official record
Conditions
Gulf War Illness
Interventions
naltrexone, Dextromethorphan
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Third-Wave Intervention for Internalized Weight Bias Combined With a Weight Loss Program

NCT05529758
View directory record Official record
Conditions
Weight Loss, Weight Prejudice
Interventions
Internalized Weight Bias Intervention
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 9, 2026, 2:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Soft and Hard Tissue Changes Around Implants

NCT05769673
View directory record Official record
Conditions
Edentulous Alveolar Ridge
Interventions
Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 9, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional

Developing a Digital Aid to Improve ICD Decisions

NCT07084142
View directory record Official record
Conditions
Heart Failure and Reduced Ejection Fraction
Interventions
Online, patient-facing decision-making aid (app) with personalized risk information., Implantable Cardioverter Defibrillator (ICD), Online, patient-facing decision-making app without personalized risk information.
Other · Device
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
San Francisco, California • Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-ingredient Supplement for Strength and Power

NCT01971723
View directory record Official record
Conditions
Supplement
Interventions
T+ Supplement, Placebo
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Public Health Program to Reduce Risk of Antepartum Depression

NCT02144844
View directory record Official record
Conditions
Depression
Interventions
Insight-Plus Cognitive Behavioral Intervention
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
2
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome

NCT05034380
View directory record Official record
Conditions
Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
Interventions
Acute exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Benzoates - an Obesogenic Endocrine Disrupting Chemical

NCT03190785
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Benzoic acid washout and exposure
Other
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Maternal Exercise on Infant Skeletal Muscle and Metabolomics

NCT03838146
View directory record Official record
Conditions
Exercise
Interventions
Types of Exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Skin Change Actions by Nursing

NCT06127524
View directory record Official record
Conditions
Pressure Injury
Interventions
SEM Scanner
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
4,733 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Kennett Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cortical Activation and Cognitive-Motor Learning

NCT04666181
View directory record Official record
Conditions
Dual-task, Healthy Adults
Interventions
Dual-task training
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 9, 2026, 2:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pregnancy Exercise Mode Effect on Childhood Obesity

NCT04805502
View directory record Official record
Conditions
Pregnancy, Overweight and Obesity
Interventions
Exercise Modes
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 9, 2026, 2:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Human Papilloma Viruses (HPV) Vaccine Adherence Community Clinic Study

NCT01908517
View directory record Official record
Conditions
Patient Compliance
Interventions
HPV Vaccine Electronic Reminders
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
9 Years to 17 Years
Enrollment
522 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Greenville, North Carolina • Snow Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Oct 9, 2026, 2:47 AM EDT