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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Integrative Skin Science and Research Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin

NCT05941065
View directory record Official record
Conditions
Skin Microboime, Acne
Interventions
Balancing gel cream
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

NCT06072066
View directory record Official record
Conditions
Rosacea, Systemic Inflammation
Interventions
Skin Barrier Oral Supplement
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

NCT05882084
View directory record Official record
Conditions
Photoaging
Interventions
Astaxanthin 6 mg daily, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Almond on Facial Skin Collagen and Wrinkles

NCT06074276
View directory record Official record
Conditions
Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
Interventions
Food: whole almonds, Food: non-nut snack
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Almond Supplementation on Mild to Moderate Acne

NCT05269641
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Food: whole almonds, Food: non-nut snack
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
15 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Sep 26, 2026, 1:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective Study of Topical Adapinoid Versus Topical Retinol

NCT05778760
View directory record Official record
Conditions
Wrinkle
Interventions
Retinol, Adapinoid
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Botanical Skin Care Regimen on Mild to Moderate Acne and the Microbiome

NCT05271487
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Multi-Step Botanical Skin Care Regimen
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
15 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 26, 2026, 1:46 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

NCT07544251
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Sarecycline, Doxycycline
Drug
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
9 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 26, 2026, 1:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation

NCT06080035
View directory record Official record
Conditions
Hyperpigmentation, Post-inflammatory Hyperpigmentation, Acne
Interventions
Topical Cetyl Tranexamate Mesylate
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
14 Years to 45 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris

NCT04596748
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
13 Years to 45 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Botanical Blend on the Gut Microbiome and Gut-Skin-Axis in Small Intestinal Bacterial Overgrowth (SIBO)

NCT04867512
View directory record Official record
Conditions
Small Intestinal Bacterial Overgrowth (SIBO)
Interventions
Liquid Tincture, GI Detox, Olivirex
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Correlation Between Objective Skin Pigment Measurement and Fitzpatrick Skin Type

NCT06144541
View directory record Official record
Conditions
Skin Pigment
Interventions
Survey administration for Fitzpatrick skin type, Measurement of ITA based on SkinColorCatch instrument
Other · Device
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Terminalia Chebula Fruit Extract on the Gut Microbiome and Skin Biophysical Properties

NCT04597502
View directory record Official record
Conditions
Human Microbiome
Interventions
Terminalia Chebula fruit extract, Placebo, Topical Terminalia Chebula, Topical Placebo
Dietary Supplement · Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
25 Years to 55 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Sep 26, 2026, 1:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Pomegranate Extract on the Microbiome and Skin Biophysical Properties

NCT04596722
View directory record Official record
Conditions
Human Microbiome
Interventions
Pomella, Placebo
Dietary Supplement · Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
25 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a Longevity Supplement on Aging and Photoaging

NCT05262036
View directory record Official record
Conditions
Photoaging
Interventions
Anti-aging Supplement, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Safety of Pulsing Heating Device Use on the Skin

NCT05427877
View directory record Official record
Conditions
Pain
Interventions
Heating device (Heatwave Technology)
Device
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

NCT06571721
View directory record Official record
Conditions
Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin, Sebum Deficiency
Interventions
Topical Product: Almond Oil, Topical Product: Almond oil augmented with 0.5% Vitamin E, Topical Product: 0.025% Tretinoin oil augmented with castor oil
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessment of the Effect of Coconut and Sunflower Seed Oil Derived Isosorbide Diseters and Colloidial Oatmeal

NCT05688735
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Isosorbide Diester Moisturizer, Control Moisturizer
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
2 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a Springtime Home Cleanse on Skin, Gut, Metabolic and Mental Health

NCT04869865
View directory record Official record
Conditions
Healthy
Interventions
9-day detoxification cleanse and 1 week of pre-cleanse transition
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years to 69 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 2, 2021 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a 3-Part Skin Care Regimen on Facial Wrinkles and Biophysical Attributes

NCT05698485
View directory record Official record
Conditions
Wrinkle
Interventions
Cleansing Balm, Facial Serum, Moisturizer
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

NCT05942248
View directory record Official record
Conditions
Acne, Melasma, Rosacea, Seborrheic Dermatitis
Interventions
No Intervention
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties

NCT05688527
View directory record Official record
Conditions
Wrinkle
Interventions
Cleansing Balm, Toning Essence, Facial Serum, Moisturizer, Eye Cream
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin

NCT06096649
View directory record Official record
Conditions
Photoaging
Interventions
Topical Vehicle + Zinc Di-(dibutyryl lisinate), Topical Vehicle
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
40 Years to 60 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Sep 26, 2026, 1:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prospective Study of Topical Vitamin C (THDA) Versus Topical Vitamin C (THDA) With Acetyl Zingerone

NCT05779280
View directory record Official record
Conditions
Wrinkle, Skin Pigmentation
Interventions
THDA + Acetyl Zingerone Topical Product, THDA
Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 26, 2026, 1:46 AM EDT