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ClinicalTrials.gov public records Last synced Oct 2, 2026, 3:21 PM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.

Filters: Sponsor: Lindner Center of HOPE Clear all

Conditions: Weight Gain
Interventions: Zonisamide, olanzapine, Sugar Pill (placebo); Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bipolar Disorder
Interventions: Quetiapine; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Binge Eating Disorder
Interventions: PHEN/TPM ER (Qsymia®); Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Binge-Eating Disorder, Circadian Rhythm Disorders
Interventions: Melatonin (3hrs before DLMO), Placebo (3hrs before DLMO), Morning light version 1, Morning light version 2; Dietary Supplement · Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 50 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bipolar Depression
Interventions: aripiprazole; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Bipolar Disorder, Depression
Interventions: Sertraline, Lithium carbonate; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 3
States / cities: Los Angeles, California • Palo Alto, California • Mason, Ohio

Conditions: Panic Disorder
Interventions: levetiracetam; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
Interventions: Ziprasidone, Placebo; Drug
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 3
States / cities: Palo Alto, California • Tampa, Florida • Mason, Ohio

Conditions: Pathological Gambling
Interventions: olanzapine, sugar pill; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 75 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Insomnia, Bipolar Disorder
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bipolar, Depression
Interventions: Lisdexamfetamine, Placebo control; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bipolar Disorder, Obesity
Interventions: LIRAGLUTIDE, Placebo; Drug · Other
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Binge Eating Disorder Associated With Obesity
Interventions: Zonegran, sugar pill; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Major Depressive Disorder
Interventions: Active transcutaneous spinal direct current stimulation, Sham transcutaneous spinal direct current stimulation; Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Smoking Cessation
Interventions: Topiramate, Placebo; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Bipolar Depression
Interventions: Mydayis Extended-Release Capsule, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 55 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Rochester, Minnesota • Mason, Ohio

Conditions: Binge-eating Disorder
Interventions: atomoxetine; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Binge Eating Disorder
Interventions: Lisdexamfetamine; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Binge Eating Disorder, Obesity
Interventions: Lamotrigine, placebo; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bulimia Nervosa
Interventions: N-acetylcysteine; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Binge Eating Disorder
Interventions: acamprosate, placebo; Drug · Other
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Binge Eating Disorder
Interventions: The subject will complete e-diary for 2 weeks, complete paper diary for 2 weeks; Other
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: Up to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Mason, Ohio

Conditions: Bipolar Disorder, Anxiety Disorder
Interventions: Risperidone; Drug
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 111 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Bipolar Spectrum Disorder With Moderate-to- Severe Hypomania or Mild Mania
Interventions: Divalproex, Placebo; Drug · Other
Lead sponsor: Lindner Center of HOPE; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Cincinnati, Ohio

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A Study of Zonisamide to Prevent Olanzapine-Associated Weight Gain

Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms

Phentermine/Topiramate Extended Release in Binge Eating Disorder (BED)

The Role of the Circadian System in Binge Eating Disorder

A Preliminary Study of the Effectiveness and Tolerability of Aripiprazole in Bipolar Depression

Bipolar II Depression: Lithium, SSRI, or the Combination

Levetiracetam Treatment of Panic Disorder and Lactate-Induced Panic Attacks

Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)

Safety and Efficacy Trial of Olanzapine in Outpatients With Pathological Gambling

Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance

Adjunctive Lisdexamfetamine (LDX) in Bipolar Depression

Saxenda® in Obese or Overweight Patients With Stable Bipolar Disorder (Investigator Initiated)

Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity

Spinal Cord Stimulation for the Treatment of Major Depressive Disorder

Safety and Efficacy Study of Topiramate to Aid in Smoking Cessation

8 Week Multi-site Study of MYDAYIS® for Bipolar Depression

Atomoxetine in the Treatment of Binge Eating Disorder

Lisdexamfetamine in Binge Eating Disorder (BED): fMRI Effects

Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity

N-acetylcysteine in the Treatment of Bulimia Nervosa

Acamprosate in the Treatment of Binge-Eating Disorder

E-diary vs Paper Diary in Binge Eating Disorder

Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder

Study of Divalproex Extended Release Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomania or Mild Mania