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Showing 1–24 of 111 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Massachusetts Institute of Technology Clear all
Completed Not applicable Interventional

Hydration Status Evaluation of Dehydrated Children With Experimental Devices

NCT02960789
View directory record Official record
Conditions
Dehydration
Interventions
Formalized clinical assessment of hydration status, Take a measurement of body weight on calibrated scales, "RF wristband" hydration status measurement, Measure capillary refill time with manual stopwatch, "CRT device" hydration status measurement
Other · Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
2 Years to 18 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects

NCT04160975
View directory record Official record
Conditions
Flu, Human, Influenza, Human, Covid19
Interventions
Video about safety and effectiveness of adult seasonal flu vaccination
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years to 51 Years · Male only
Enrollment
3,245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional

Treatment Choice and Outcomes for ESRD: Evidence From the First Year of a Nationwide Randomized Evaluation

NCT05005572
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
Payment adjustment for home dialysis and transplant
Other
Lead sponsor
Amy Finkelstein
Other
Eligibility
66 Years and older
Enrollment
18,621 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Doctors for Coronavirus Prevention Project Thanksgiving / Christmas Messaging Campaign

NCT04644328
View directory record Official record
Conditions
Covid19
Interventions
Facebook Ads on the importance of staying safe during the Thanksgiving / Christmas holiday
Behavioral
Lead sponsor
National Bureau of Economic Research, Inc.
Other
Eligibility
18 Years and older
Enrollment
820 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 1, 2026, 1:53 PM EDT
Active, not recruiting Not applicable Interventional

Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

NCT04055376
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer Dementia
Interventions
GENUS device (Active Settings), GENUS device (Sham Settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
50 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Social Stress on Brain Imaging

NCT05591404
View directory record Official record
Conditions
Social Stress
Interventions
Trier Social Stress Test (TSST)
Behavioral
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Recruiting Not applicable Interventional

MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick

NCT05968157
View directory record Official record
Conditions
Breast Cancer
Interventions
Breast MRI, MIRAI
Diagnostic Test · Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
40 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gamma Frequency Stimulation in Individuals With Down Syndrome

NCT05196984
View directory record Official record
Conditions
Down Syndrome
Interventions
GENUS device (Active Settings), GENUS device (Sham Settings)
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
25 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Active, not recruiting Not applicable Interventional

Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees

NCT06391697
View directory record Official record
Conditions
Amputation
Interventions
eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Terminated Phase 2 Interventional Results available

Prevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT)

NCT02417974
View directory record Official record
Conditions
Crohn's Disease
Interventions
Fecal Microbiota Transplant (FMT)
Biological
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Sep 1, 2026, 1:53 PM EDT
Terminated Not applicable Interventional

Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.

NCT02470728
View directory record Official record
Conditions
Pain, Acute Pain, Postoperative Pain
Interventions
New Clinical Pathway
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Orange, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 1, 2026, 1:53 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Active Knee Prosthesis Study for Improvement of Locomotion for Above Knee Amputees

NCT00771589
View directory record Official record
Conditions
Amputation
Interventions
Active Knee Prosthesis
Device
Lead sponsor
Providence VA Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Cambridge, Massachusetts • North Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 12, 2008 · Synced Sep 1, 2026, 1:53 PM EDT
Enrolling by invitation No phase listed Observational

Shortwave Infrared Surgical Imaging Device Study

NCT07744425
View directory record Official record
Conditions
Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism, Sigmoid Colon Diverticulitis, Multinodular Goiter, Thyroid and Parathyroid Surgery
Interventions
Observational study of SWIR imaging device in surgery
Device
Lead sponsor
Cision Vision, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
6
States / cities
Palo Alto, California • Evanston, Illinois • Glenview, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fulfillment Center Study on Work, Health, and Wellbeing

NCT05199415
View directory record Official record
Conditions
Psychological Distress, Psychological Well-being, Subjective Health, Injuries
Interventions
Health and Well-being Committee
Behavioral
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
3,459 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Sep 1, 2026, 1:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Development and Testing of an Electronic Tool to Measure Physical Activity in Domestic Settings

NCT00207181
View directory record Official record
Conditions
Cancer
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2011 · Synced Sep 1, 2026, 1:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

NCT05776641
View directory record Official record
Conditions
Alzheimer Disease, Family Members
Interventions
GENUS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans

NCT07508722
View directory record Official record
Conditions
Healthy Volunteers, no Condition, Basic Science
Interventions
Transcranial Focused Ultrasound Stimulation, Electroencephalography, Magnetic Resonance Imaging
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
21 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Family-Focused Treatment for Youth Depression

NCT06289010
View directory record Official record
Conditions
Childhood Depression
Interventions
Family-Focused Treatment for Childhood-Depression (FFT-CD)
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
7 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional

Analyzing the Impact of the Now iKnow Health Care Price Transparency Tool

NCT02053844
View directory record Official record
Conditions
no Specific Condition Targeted, Use of a Price Transparency Tool
Interventions
lottery for tool users to win a $500 prize, enhanced promotion of the tool to employers and members
Other
Lead sponsor
Alison Galbraith
Other
Eligibility
Not listed
Enrollment
81,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Wellesley, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Phase 4 Interventional

Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)

NCT06584942
View directory record Official record
Conditions
Cue-reactivity, Cannabis Use Disorder, Functional MRI, Orexin Antagonist
Interventions
Suvorexant
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional Results available

Fresh Food Farmacy: A Randomized Controlled Trial

NCT03718832
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Fresh Food Farmacy
Other
Lead sponsor
John B Bulger, DO
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Lewistown, Pennsylvania • Scranton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Sep 1, 2026, 1:53 PM EDT
Completed Not applicable Interventional

Sense2Stop:Mobile Sensor Data to Knowledge

NCT03184389
View directory record Official record
Conditions
Stress, Smoking Cessation, Overeating
Interventions
Prompt to use smartphone apps for stress management
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Sep 1, 2026, 1:53 PM EDT
Terminated Not applicable Interventional Results available

Entrainment-Based Mechanical Ventilation

NCT03512067
View directory record Official record
Conditions
Respiratory Insufficiency, Respiratory Failure, Mechanical Ventilation Complication
Interventions
Patients given EMV Ventilation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 1, 2026, 1:53 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models

NCT06140823
View directory record Official record
Conditions
Predictive Cancer Model
Interventions
Liver Risk Computation Model (LIRIC), Liver Risk Computation Model (LIRIC)_cirrhosis, Liver Risk Computation Model (LIRIC)_no_cirrhosis
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years to 100 Years
Enrollment
6,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 1, 2026, 1:53 PM EDT