- Conditions
- Urothelial Carcinoma Recurrent, Advanced Urothelial Carcinoma
- Interventions
- Vactosertib(TEW-7197)/ Durvalumab
- Drug
- Lead sponsor
- MedPacto, Inc.
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 2
- States / cities
- San Francisco, California • Buffalo, New York
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- Conditions
- Myelodysplastic Syndromes
- Interventions
- TEW-7197
- Drug
- Lead sponsor
- MedPacto, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Baltimore, Maryland • The Bronx, New York
- Conditions
- Metastatic Malignant Neoplasm in the Liver, Stage IV Colorectal Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8
- Interventions
- Hepatectomy, Pembrolizumab, Vactosertib
- Procedure · Biological · Drug
- Lead sponsor
- Chloe Atreya, MD, PhD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Osteosarcoma
- Interventions
- Vactosertib
- Drug
- Lead sponsor
- MedPacto, Inc.
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Advanced Stage Solid Tumors
- Interventions
- TEW-7197
- Drug
- Lead sponsor
- MedPacto, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 3
- States / cities
- Durham, North Carolina • Nashville, Tennessee