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ClinicalTrials.gov public records Last synced Oct 16, 2026, 11:21 AM EDT

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Showing 1–24 of 1,056 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Medical University of South Carolina Clear all
Active, not recruiting Phase 3 Interventional

ACHIEVE Brain Health Follow-Up Study

NCT05532657
View directory record Official record
Conditions
Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia, Hearing Loss
Interventions
Hearing intervention, Successful aging/delayed hearing intervention
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
73 Years and older
Enrollment
629 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Hagerstown, Maryland • Minneapolis, Minnesota • Jackson, Mississippi + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 4 Interventional Results available

Pioglitazone and Serum Asymmetric Dimethylarginine (ADMA) in Patients With Diabetes

NCT00770367
View directory record Official record
Conditions
Diabetes
Interventions
Pioglitazone then Placebo, Placebo then Pioglitazone
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Terminated Not applicable Interventional Results available

Myocardial Stress Perfusion Computed Tomography in the Evaluation of Patients With Acute Chest Pain Using a Novel 3rd Generation Dual-source CT System

NCT02308475
View directory record Official record
Conditions
Chest Pain
Interventions
Somatom Force CT Scanner
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

NCT06922617
View directory record Official record
Conditions
Tobacco Use, Substance Use Disorders
Interventions
Switching to E-Cigarette, Quitting using Medication, Counseling
Behavioral · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Charleston, South Carolina • Conway, South Carolina • Greenville, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 2Phase 3 Interventional

Communication During Hospitalization About Resuscitation Trial

NCT02984124
View directory record Official record
Conditions
Severe Life-limiting COPD, Severe Life-limiting Heart Failure, Severe Life-limiting Cirrhosis, Severe Life-limiting Malignancy, Severe Functional Impairment, End Stage Renal Disease
Interventions
Informed Assent Discussion, Usual Care with Attention Control
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
65 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Charleston, South Carolina • Burlington, Vermont + 1 more
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional

Parent Educational Discharge Support Strategies

NCT03227068
View directory record Official record
Conditions
Educational Activities
Interventions
PEDSS - symptom management, PEDSS - support for the caregiver
Other
Lead sponsor
Duke University
Other
Eligibility
3 Years to 17 Years
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
15
States / cities
Miami, Florida • Chicago, Illinois • Winfield, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 16, 2026, 11:21 AM EDT
Completed No phase listed Observational

Balloon Cryotherapy vs. Radiofrequency Ablation Pain Study

NCT03387982
View directory record Official record
Conditions
Barrett Esophagus
Interventions
Not listed
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Queens, New York • Danville, Pennsylvania • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2022 · Synced Oct 16, 2026, 11:21 AM EDT
Terminated Not applicable Interventional Results available

PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor

NCT03401489
View directory record Official record
Conditions
Blood Pressure, Hypertension, Mhealth
Interventions
PACESETTER
Device
Lead sponsor
Northern California Institute of Research and Education
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
San Francisco, California • Charleston, South Carolina • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional Results available

Post-stroke Pain taVNS

NCT06456385
View directory record Official record
Conditions
Stroke, Pain
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Auricular Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 16, 2026, 11:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gadolinium Retention in Human Bone Tissue in Pediatric Patients

NCT03337594
View directory record Official record
Conditions
Gadolinium, MultiHance, Dotarem, Magnetic Resonance Imaging, Gadolinium Retention
Interventions
Pre-operative MRI with Dotarem, Pre-operative MRI with MultiHance, Surgery
Drug · Procedure
Lead sponsor
Donna Roberts
Other
Eligibility
Up to 18 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional

Management of Allergic Rhinitis Patients With Nasal Steroids and NeilMed® Sinus Rinse™ System With Isotonic Saline

NCT01030146
View directory record Official record
Conditions
Rhinitis
Interventions
NeilMed® Sinus Rinse™ System with Isotonic Saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness

NCT00078741
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Schizophrenia
Interventions
Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Charleston, South Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Oct 16, 2026, 11:21 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

tFUS to Enhance Alertness and Performance

NCT06461221
View directory record Official record
Conditions
Reaction Time, Alertness
Interventions
Transcranial Focused Ultrasound
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 3 Interventional

Dose Response Trial of Pergolide for Cocaine Dependence - 1

NCT00000248
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Pergolide
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1996
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 1Phase 2 Interventional

Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation

NCT01509599
View directory record Official record
Conditions
Venous Disease, Venous Vascular Diseases and Syndromes, Venous Insufficiency, Venous Ulcers
Interventions
Cryotherapy: Cooling gel wrap, Usual care
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Charleston, South Carolina • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 16, 2026, 11:21 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Labor Epidurals for Postpartum Tubal Ligation

NCT02564016
View directory record Official record
Conditions
Pregnancy
Interventions
Normal Saline Infusion, Capped Epidural
Drug · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 2 Interventional Results available

SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity

NCT02819856
View directory record Official record
Conditions
Ototoxicity
Interventions
Placebo, SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 2 Interventional Results available

Bevacizumab and Erlotinib or Sorafenib as First-Line Therapy in Treating Patients With Advanced Liver Cancer

NCT00881751
View directory record Official record
Conditions
Liver Cancer
Interventions
bevacizumab, erlotinib hydrochloride, sorafenib tosylate
Biological · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 116 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
6
States / cities
Los Angeles, California • San Francisco, California • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional

Adherence Enhancement for Renal Transplant Patients

NCT01859273
View directory record Official record
Conditions
Renal Failure, Medication Adherence, Hypertension
Interventions
mHealth
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2016 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional Results available

Musical Engagement of Brain LObes in Alzheimer's Disease Patients StudY

NCT05309369
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Music Therapy
Interventions
Preferred Music, Nature Sounds
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
55 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Not applicable Interventional Results available

Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds

NCT02638298
View directory record Official record
Conditions
Sarcoma, Cancer, Infectious Disease
Interventions
Prevana Dressing, Standard Dry Gauze Dressing
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 16, 2026, 11:21 AM EDT
Completed Phase 3 Interventional Results available

Use of N-Acetylcysteine (NAC) in Fingernail Biting

NCT01993849
View directory record Official record
Conditions
Onychophagia
Interventions
N-Acetylcysteine (NAC), Placebo
Drug · Other
Lead sponsor
Kevin Gray, MD
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 16, 2026, 11:21 AM EDT
Active, not recruiting Not applicable Interventional

MITIGAAT: Multifaceted Intervention To Improve Graft Outcome Disparities in African American Kidney Transplants

NCT06023615
View directory record Official record
Conditions
Medication Adherence, Medication Compliance
Interventions
mHealth app/dashboard
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 16, 2026, 11:21 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Endothelial Progenitor Cells in Umbilical Cord Blood in Preeclampsia and IUGR

NCT00634855
View directory record Official record
Conditions
Preeclampsia, IUGR
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 16, 2026, 11:21 AM EDT