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Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Merz North America, Inc. Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color

NCT01012388
View directory record Official record
Conditions
Nasolabial Folds
Interventions
Radiesse® Injectable Dermal Filler
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
5
States / cities
Los Angeles, California • Chevy Chase, Maryland • Ypsilanti, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 3 Interventional Results available

Evaluation of the Efficacy and Safety of NAFT-600 in Subjects With Tinea Pedis

NCT01290341
View directory record Official record
Conditions
Tinea Pedis
Interventions
NAFT-600 (naftin 2 % gel), Placebo
Drug
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
12 Years and older
Enrollment
860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
23
States / cities
Tucson, Arizona • Encino, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2013 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Single-Center Investigator-Initiated Evaluator-Bilateral-Comparison Pilot Study of Injectable Calcium Hydroxylapatite With and Without Triamcinolone Acetate for the Treatment of Volume Loss to Dorsum Areas of the Hands

NCT02454088
View directory record Official record
Conditions
Volume Loss to Dorsum of Hands
Interventions
Calcium Hydroxylapatite and Triamcinolone acetate, Calcium Hydroxylapatite and Placebo
Other · Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial Lines

NCT04594213
View directory record Official record
Conditions
Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
Interventions
NT 201, Placebo
Drug
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
12
States / cities
Encino, California • Newport Beach, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effectiveness and Safety of the Ulthera™ System for the Treatment of Wrinkles Around the Eyes

NCT00747422
View directory record Official record
Conditions
Periorbital Wrinkles
Interventions
Ulthera™ System
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
40 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
4
States / cities
San Diego, California • Chicago, Illinois • Chestnut Hill, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Radiesse® Dermal Filler for Hand Treatment

NCT01832090
View directory record Official record
Conditions
Aging Hands
Interventions
Radiesse® Injectable Dermal Filler
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
6
States / cities
San Diego, California • Vista, California • Garden City, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed No phase listed Observational

Trial Evaluating Xeomin® (incobotulinumtoxinA) for Cervical Dystonia or Blepharospasm in the United States

NCT01287247
View directory record Official record
Conditions
Cervical Dystonia, Blepharospasm
Interventions
Xeomin®
Biological
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
688 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
70
States / cities
Cullman, Alabama • Scottsdale, Arizona • Tucson, Arizona + 60 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2015 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

This is a Post Approval Study of Coaptite® in the Treatment of Female Urinary Incontinence

NCT00996489
View directory record Official record
Conditions
Female Stress Urinary Incontinence Due to Intrinsic Sphincter Deficiency
Interventions
Coaptite®
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
459 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
20
States / cities
Wetumpka, Alabama • Surprise, Arizona • Encinitas, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Wrinkles Around the Eyes Using the Ulthera® System

NCT01368900
View directory record Official record
Conditions
Periorbital Wrinkles
Interventions
Ulthera® System treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Hunt Valley, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 2 Interventional Results available

Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines

NCT03806933
View directory record Official record
Conditions
Moderate to Severe Glabellar Frown Lines
Interventions
NT 201
Drug
Lead sponsor
Merz Aesthetics GmbH
Industry
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
5
States / cities
Encino, California • Newport Beach, California • San Diego, California + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles

NCT05163353
View directory record Official record
Conditions
Décolleté Wrinkles
Interventions
Treatment with diluted Radiesse
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
9
States / cities
Beverly Hills, California • Redondo Beach, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.

NCT00876265
View directory record Official record
Conditions
Facial Wrinkles
Interventions
Belotero, Zyplast
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
6
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Sep 1, 2026, 10:05 PM EDT
Terminated No phase listed Observational

Longitudinal Evaluation and Real-world Evidence of NT201

NCT05222607
View directory record Official record
Conditions
Glabellar Frown Lines and Canthal Lines and/or Horizontal Forehead Lines in the Upper Face
Interventions
IncobotulinumtoxinA
Drug
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiesse® Safety Study For the Treatment of Hands

NCT02904096
View directory record Official record
Conditions
Volume Loss in the Dorsum of the Hand
Interventions
Radiesse injectable implant and 2% lidocaine HCL
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
22 Years and older
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
9
States / cities
Sacramento, California • San Diego, California • Vista, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Ulthera® System for Treatment of the Brachia

NCT01713933
View directory record Official record
Conditions
Brachial Ptosis
Interventions
Ulthera® System
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
19 Years to 55 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 4 Interventional Results available

The Treatment of Glabellar Frown Lines

NCT02096081
View directory record Official record
Conditions
Glabellar Frown Lines
Interventions
IncobotulinumtoxinA, OnabotulinumtoxinA
Drug
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
10
States / cities
Los Angeles, California • Sacramento, California • Santa Monica, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Terminated Phase 2 Interventional Results available

Incobotulinum Toxin for the Treatment of Trigeminal Neuralgia

NCT02088632
View directory record Official record
Conditions
Trigeminal Neuralgia
Interventions
Incobotulinumtoxina, Placebo Comparator
Biological · Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Lifting and Tightening Neck Skin in Patients

NCT01708928
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Retrospective Study to Evaluate the Effectiveness of the Ulthera System

NCT01519934
View directory record Official record
Conditions
Skin Laxity, Wrinkles
Interventions
Not listed
Lead sponsor
Ulthera, Inc
Industry
Eligibility
25 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional

Feasibility Study: Ulthera® System for the Treatment of Moderate to Severe Facial Acne

NCT01591304
View directory record Official record
Conditions
Facial Acne
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Woodland Hills, California • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Not applicable Interventional Results available

Effectiveness and Safety of the Octave System for Lifting the Eyebrow and Improving the Appearance of the Face and Neck

NCT05067504
View directory record Official record
Conditions
Eyebrow Lift, Improved Appearance of the Face and Neck
Interventions
Octave-Ultherapy treatment
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Vista, California • Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 2 Interventional

A Study of NT 201 Doses in the Treatment of Platysma Prominence

NCT05773053
View directory record Official record
Conditions
Platysma Prominence
Interventions
NT 201, NT 201 Placebo
Drug
Lead sponsor
Merz Aesthetics GmbH
Industry
Eligibility
18 Years to 65 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Aventura, Florida • Coral Gables, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2024 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Belotero Post Approval Study

NCT01635855
View directory record Official record
Conditions
Nasolabial Folds
Interventions
Belotero®
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
9
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Sep 1, 2026, 10:05 PM EDT
Completed Phase 2 Interventional Results available

A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of IncobotulinumtoxinA Versus Saline Injections to the Cheek Region in Patients With Rosacea

NCT01614743
View directory record Official record
Conditions
Rosacea
Interventions
IncobotulinumtoxinA, Bacteriostatic saline
Drug
Lead sponsor
DeNova Research
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 1, 2026, 10:05 PM EDT