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ClinicalTrials.gov public records Last synced Oct 8, 2026, 4:20 AM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Midwest Center for Metabolic and Cardiovascular Research Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Acute Intake of Meals Containing Higher vs. Lower Energy From Protein on DIT

NCT06494449
View directory record Official record
Conditions
Healthy, Overweight and Obesity
Interventions
Higher protein, Lower protein
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess the Effects of Diets With and Without Inulin on Energy Expenditure in Adults.

NCT06923332
View directory record Official record
Conditions
Healthy, Overweight or Obese Adults
Interventions
High Fiber bar with Inulin, Low fiber bar - no inulin
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Diets Containing Beef vs. Poultry on Pancreatic Beta-Cell Function

NCT05456477
View directory record Official record
Conditions
PreDiabetes
Interventions
Beef, Poultry
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.

NCT03332927
View directory record Official record
Conditions
PreDiabetes
Interventions
Egg based breakfast foods, Non-egg based breakfast foods
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 8, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

NCT07566325
View directory record Official record
Conditions
Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
Interventions
Avocado, Control
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Dietary Supplement on Lipoprotein Lipids and Inflammatory Markers

NCT03118583
View directory record Official record
Conditions
Healthy Volunteers
Interventions
300 mg/day of dietary supplement containing carrageenan
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
25 Years to 69 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Effects of Lean Pork, High Protein Breakfast on Satiety and Metabolic Health in Pre-diabetes

NCT02934425
View directory record Official record
Conditions
Pre-diabetes
Interventions
Refined carbohydrate-rich breakfast, High pork protein breakfast
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Gastrointestinal Responses to Dietary Fibers in Adults Using Weight Loss Medications

NCT07012317
View directory record Official record
Conditions
Gastrointestinal Symptoms, Weight Loss, GLP-1
Interventions
High Fiber Bar with Inulin, High Fiber bar with Fiber Blend, High Fiber Bar with Resistant Starch type 4, Low Fiber Bar
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
25 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Miami Gardens, Florida • Port Saint Lucie, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Full-fat or Low-fat Dairy Foods on Insulin Sensitivity, RBC FA's and Other Markers of Metabolic Health

NCT04999462
View directory record Official record
Conditions
Overweight and Obesity, Elevated Triglycerides
Interventions
Full-fat fermented dairy, Low-fat fermented dairy, Non-dairy, non-fermented foods
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
4
States / cities
Miami Gardens, Florida • Chicago, Illinois • Gurnee, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Understand How Continuous Glucose Monitors Impact Eating Behavior

NCT06269094
View directory record Official record
Conditions
Weight Loss
Interventions
CGM
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Two Coenzyme Q10 Products in Men and Women

NCT07530250
View directory record Official record
Conditions
CoQ10 Blood Levels
Interventions
high absorption CoQ10 product, standard CoQ10 product
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of Select Nutrients From Two Formulations of a Multivitamin/Mineral Supplement

NCT05646368
View directory record Official record
Conditions
Bioavailability
Interventions
Formulation #1, Formulation #2
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Port Saint Lucie, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults

NCT03562468
View directory record Official record
Conditions
Cognitive Function, Mood, Sleep
Interventions
300 mg/day of TRU NIAGEN (nicotinamide riboside), 1000 mg/day of TRU NIAGEN (nicotinamide riboside), Placebo
Dietary Supplement
Lead sponsor
ChromaDex, Inc.
Industry
Eligibility
55 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Appearance of Amino Acids in Circulation Following Consumption of Protein Beverages

NCT07293091
View directory record Official record
Conditions
Gastrointestinal Tolerability, Appetite, Amino Acids
Interventions
Protein Powder, Control Protein Powder
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
25 Years to 54 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami Gardens, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

NCT04990817
View directory record Official record
Conditions
Elevated Triglycerides, Hypertriglyceridemia
Interventions
Average American Diet With SoFAS Replaced With Avocado, Average American Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Bitter Melon on Cardiometabolic Health

NCT05540405
View directory record Official record
Conditions
PreDiabetes
Interventions
Low-dose bitter melon, High-dose bitter melon, Placebo
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Miami Gardens, Florida • Port Saint Lucie, Florida • Addison, Illinois
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release

NCT05287906
View directory record Official record
Conditions
Overweight and Obesity, Type 2 Diabetes Mellitus
Interventions
Water, Glucose, Steviol Glycosides, Steviol Glycosides plus glucose, Rebaudioside A
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 50 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
3
States / cities
Miami Gardens, Florida • Naples, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses

NCT03796286
View directory record Official record
Conditions
Blood Glucose, Insulin Sensitivity, Dietary Fiber
Interventions
Medium-fiber bar, High-fiber bar, Control bar (0 g fiber)
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boca Raton, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 8, 2026, 4:20 AM EDT
Terminated Not applicable Interventional

Effects of Ergothioneine on Cognition, Mood, and Sleep in Healthy Adult Men and Women

NCT04556032
View directory record Official record
Conditions
Healthy
Interventions
L-Ergothioneine 10 mg/d, L-Ergothioneine 25 mg/d, Placebo
Dietary Supplement · Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
55 Years to 79 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Lactoferrin at Two Doses vs. Active Control on Markers of Immune Function

NCT06012669
View directory record Official record
Conditions
Immune Health
Interventions
High dose Human Lactoferrin, Low dose Human Lactoferrin, Active Control Bovine Lactoferrin
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 45 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Miami, Florida • Port Saint Lucie, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 8, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)

NCT07789769
View directory record Official record
Conditions
Overweight , Obesity
Interventions
30-30-30 PFE Intervention, Standard
Behavioral
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 69 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Addison, Illinois • Chicago, Illinois • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of EPA/DHA in of Ruby-O and Krill Oil

NCT05438173
View directory record Official record
Conditions
Bioavailability
Interventions
EPA + DHA Ruby-O, EPA + DHA Krill Oil
Dietary Supplement
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Port Saint Lucie, Florida
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes

NCT03202680
View directory record Official record
Conditions
Metabolic Syndrome, PreDiabetes
Interventions
USDA Style Diet, Lean Beef Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 8, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of EPA + DHA in a SMEDS Formulation

NCT03443076
View directory record Official record
Conditions
Bioavailability
Interventions
EPA + DHA in SMEDS Formulation, Lovaza (active comparator; already FDA approved)
Dietary Supplement · Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Boca Raton, Florida • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 8, 2026, 4:20 AM EDT