- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Computerized Cognitive Skill Training, CRT and Social Cognition
- Behavioral
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 448 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
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Showing 1–24
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- Conditions
- Schizophrenia
- Interventions
- D-serine
- Drug
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 3
- States / cities
- New Haven, Connecticut • Glen Oaks, New York • Orangeburg, New York
- Conditions
- Diabetes, Schizophrenia, Insulin Resistance, Cognitive Impairment
- Interventions
- Pioglitazone, Life style diet group, Placebo
- Drug · Behavioral · Other
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia
- Interventions
- Visual Training
- Behavioral
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Piscataway, New Jersey
- Conditions
- Schizophrenia
- Interventions
- MK-0777, placebo
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Catonsville, Maryland • Boston, Massachusetts + 4 more
- Conditions
- Mental Health
- Interventions
- Critical Time Intervention
- Behavioral
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Months to 16 Years
- Enrollment
- 320 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2002 – 2005
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Schizophrenia, Cigarette Smoking
- Interventions
- Varenicline, Placebo for varenicline
- Drug
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 2
- States / cities
- New York, New York • Orangeburg, New York
- Conditions
- Schizophrenia
- Interventions
- AL-108, Placebo
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Catonsville, Maryland • Boston, Massachusetts + 4 more
- Conditions
- Cannabis Use, Depression
- Interventions
- Neuroimaging Investigation
- Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 14 Years to 20 Years
- Enrollment
- 280 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 2
- States / cities
- Miami, Florida • Orangeburg, New York
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- D-serine, placebo, Sensory Based remediation paradigm
- Drug · Behavioral
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Obsessive Compulsive Disorder
- Interventions
- glycine, placebo
- Drug · Other
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Borderline Personality Disorder
- Interventions
- Ketamine, Midazolam
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut
- Conditions
- Opioid Use Disorder
- Interventions
- PRC supported text + AI driven SDH-enhanced text, AI driven SDH-enhanced text only, Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- Friends Research Institute, Inc.
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 292 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Post-Traumatic Stress Disorder
- Interventions
- STAIR/NT treatment, Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- Palo Alto Veterans Institute for Research
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 5
- States / cities
- Farmington, Connecticut • Washington D.C., District of Columbia • Atlanta, Georgia + 2 more
- Conditions
- Heart Failure
- Interventions
- Pyridostigmine Bromide
- Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia, Cognition, Cigarette Smoking
- Interventions
- tDCS
- Device
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Schizophrenic Disorders, Cognitive Function
- Interventions
- Sodium Butyrate, Placebo
- Dietary Supplement · Other
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Schizophrenia
- Interventions
- Org 24448, Placebo
- Drug · Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 55 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Catonsville, Maryland • Boston, Massachusetts + 4 more
- Conditions
- Schizophrenia, Schizo Affective Disorder
- Interventions
- D-serine, Placebo
- Drug
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- New York, New York • Orangeburg, New York
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Active Transcranial direct current stimulation (tDCS), Sham Transcranial direct current stimulation (tDCS), Auditory Remediation, Control computer activities
- Device · Behavioral
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Depressive Disorder, Treatment-Resistant
- Interventions
- Ketamine Hydrochloride
- Drug
- Lead sponsor
- Dan Iosifescu
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Capsule with folate, Vitamin B12 & pyridoxine, placebo
- Dietary Supplement · Other
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Orangeburg, New York
- Conditions
- Schizophrenia
- Interventions
- Cognitive remediation therapy
- Behavioral
- Lead sponsor
- Manhattan Psychiatric Center
- Other
- Eligibility
- 18 Years to 55 Years · Male only
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Schizophrenia
- Interventions
- D-serine
- Drug
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Orangeburg, New York