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ClinicalTrials.gov public records Last synced Oct 8, 2026, 9:10 AM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: National Aeronautics and Space Administration (NASA) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Intake Modifications to Protect Against Changes in Bone Metabolism

NCT01713634
View directory record Official record
Conditions
Bone Resorption
Interventions
Preflight, In-flight
Other
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
Not listed
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2015 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fatigue Countermeasure Program in Operational Flight Controllers

NCT01744678
View directory record Official record
Conditions
Fatigue
Interventions
blue-wavelength enriched ceiling light, mild exercise
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2019 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults

NCT03911154
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 8, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Artemis Sleep Countermeasures

NCT06531733
View directory record Official record
Conditions
Fatigue
Interventions
Sleep Promoting (pink noise), Wake Promoting (blue enriched light plus a nap)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Noisy Galvanic Vestibular Stimulation Frequency Range for Enhancing Vestibular Perception and Manual Control Performance

NCT07730398
View directory record Official record
Conditions
Vestibular Function Tests, Sensorimotor Performance
Interventions
Low-frequency noisy galvanic vestibular stimulation (nGVS), High-frequency noisy galvanic vestibular stimulation (nGVS)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
22 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 8, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of ACEI on Bone Turnover

NCT02377440
View directory record Official record
Conditions
Bone Turnover Status in Hypertensive Patients
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2015 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity

NCT06214468
View directory record Official record
Conditions
Drug Toxicity
Interventions
Acetaminophen and Nicotinamide Riboside, Acetaminophen
Combination Product · Drug
Lead sponsor
University of South Alabama
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 8, 2026, 9:10 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

NCT05886660
View directory record Official record
Conditions
Motion Sickness, Space, Motion Sickness, Sea Sickness
Interventions
DPI-386 Nasal Gel, Placebo Nasal Gel
Drug
Lead sponsor
Repurposed Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 8, 2026, 9:10 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome

NCT02896452
View directory record Official record
Conditions
Polycystic Ovarian Syndrome, Idiopathic Intracranial Hypertension
Interventions
Not listed
Lead sponsor
National Aeronautics and Space Administration
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

NCT04856410
View directory record Official record
Conditions
Brain Structure, Cognitive Performance
Interventions
Spaceflight, Controls
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Microgravity Effects on Co-cultured Vascular Cells Types

NCT03144492
View directory record Official record
Conditions
Microgravity Exposed Endothelial Cells
Interventions
Blood volume collected specifically for this study
Biological
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 50 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NM Balance Regulation With ULLS and Loss of Sleep

NCT05956964
View directory record Official record
Conditions
Muscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
Interventions
Sleep Restriction, Sleep Adequate
Behavioral
Lead sponsor
Lance Bollinger
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

NASA Prebreathe Study

NCT06740305
View directory record Official record
Conditions
Decompression Sickness
Interventions
Altitude, 100% Oxygen
Other · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

rTMS to Enhance Cognitive Performance and Promote Resilience

NCT04123496
View directory record Official record
Conditions
Cognition, Stress Reaction
Interventions
rTMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of DHEA/Exercise on Bone, Muscle and Balance

NCT00664053
View directory record Official record
Conditions
Osteoporosis, Frailty
Interventions
DHEA, Yoga, Placebo, Aerobics
Dietary Supplement · Behavioral
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
65 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2008 · Synced Oct 8, 2026, 9:10 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fluid Loading Countermeasures

NCT06467812
View directory record Official record
Conditions
Healthy
Interventions
Salt Tablets, Electrolyte Solution
Dietary Supplement
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
25 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2024 · Synced Oct 8, 2026, 9:10 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Fatigue in Long-Haul Operations

NCT07761611
View directory record Official record
Conditions
Alertness, Fatigue, Mood, and Performance, Calorie Restriction and Light Intervention
Interventions
Caloric restriction, Light exposure
Behavioral · Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 8, 2026, 9:10 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

B-Complex: A Nutraceutical SANS Countermeasure

NCT05366933
View directory record Official record
Conditions
Optic Disc Edema, Endothelial Dysfunction
Interventions
Vitamin B-Complex Supplement
Drug
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
20 Years to 100 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

FIT Exercise in 30d of ULLS-induced Muscle Disuse

NCT06631053
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness
Interventions
velocity-based FIT (VBFIT), No Exercise
Other
Lead sponsor
Lance Bollinger
Other
Eligibility
35 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

NCT05852730
View directory record Official record
Conditions
Motion Sickness, Space, Motion Simulation, Parabolic Flight
Interventions
DPI-386 Nasal Gel, Other (e.g., promethazine, meclizine)
Drug
Lead sponsor
Repurposed Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 8, 2026, 9:10 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Human Research Program Flight Thigh Cuff

NCT06476106
View directory record Official record
Conditions
Healthy
Interventions
Venoconstrictive Thigh Cuff (VTC)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent

NCT06467825
View directory record Official record
Conditions
Healthy
Interventions
Potassium Supplement, Furosemide 20 MG, Compression Garment
Drug · Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
25 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight

NCT03786016
View directory record Official record
Conditions
Resilience, Mood, Performance, Stress, Psychological
Interventions
8-Days in an Isolation, Confinement Unit
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 8, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motion Fidelity Effects With Mixed-Reality

NCT07129876
View directory record Official record
Conditions
Healthy
Interventions
Simulator Motion
Other
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 8, 2026, 9:10 AM EDT