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ClinicalTrials.gov public records Last synced Oct 8, 2026, 5:49 PM EDT

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Showing 1–24 of 258 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: National Institute of Environmental Health Sciences (NIEHS) Clear all
Completed Not applicable Interventional

Home Air Filtration for Traffic-Related Air Pollution

NCT04279249
View directory record Official record
Conditions
Cardiovascular Risk Factor, Blood Pressure
Interventions
HEPA Air Filtration, Sham HEPA Air Filtration
Other
Lead sponsor
UConn Health
Other
Eligibility
30 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 1, 2024 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Estrogen Receptor Gene Mutations

NCT00342498
View directory record Official record
Conditions
Mutations, Hormones
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2008
U.S. locations
2
States / cities
Research Triangle Park, North Carolina • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

NCT00055055
View directory record Official record
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
2 Years and older
Enrollment
1,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
3
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers

NCT00654134
View directory record Official record
Conditions
Healthy Adults
Interventions
Clinical Center Reference Endotoxin
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

NCT00043992
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
15 Years to 50 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2006 · Synced Oct 8, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)

NCT07758114
View directory record Official record
Conditions
Environmental Exposure, Pregnancy Related, Preterm Birth, Chronic Respiratory Disease, Neurodegenerative Diseases
Interventions
Educational Intervention
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

COVID-19 Experiences in the SELF Cohort

NCT05369611
View directory record Official record
Conditions
COVID-19
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
23 Years to 35 Years · Female only
Enrollment
1,197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Pesticide Exposure and Health Status in North Carolina African American Male Farmers and Farm Workers

NCT00341965
View directory record Official record
Conditions
Pesticide Exposure
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older · Male only
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2013
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Oct 8, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Short Course of Gamma Tocopherol Supplementation in Adult Subjects

NCT02610829
View directory record Official record
Conditions
Gamma Tocopherol Serum Levels
Interventions
Gamma tocopherol
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 8, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ozone Cardiovascular Effects in Genetically Susceptible People

NCT01192477
View directory record Official record
Conditions
Healthy
Interventions
Ozone
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gene-Environment Interaction in Prostate Cancer

NCT00041847
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Up to 69 Years · Male only
Enrollment
881 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 8, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Family-Based Intervention Study of the Effects of Environmental Exposures on Breast Tissue Composition

NCT04265547
View directory record Official record
Conditions
Breast Cancer Risk
Interventions
Breast Cancer Risk Reduction Household Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 65 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 8, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional

AIRWEIGHS: Investigating Obesity as a Susceptibility Factor for Air Pollution in Childhood Asthma

NCT02763917
View directory record Official record
Conditions
Asthma
Interventions
Active Air Purifier, Placebo Air Purifier
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 8, 2026, 5:49 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults

NCT00838851
View directory record Official record
Conditions
Healthy Controls
Interventions
Clinical Center Reference Endotoxin (CCRE)
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2012 · Synced Oct 8, 2026, 5:49 PM EDT
Terminated Not applicable Interventional Results available

Dietary Interventions in Asthma Treatment: Sprouts Study

NCT01183923
View directory record Official record
Conditions
Asthma, Allergy
Interventions
Broccoli Sprouts, Alfalfa Sprouts
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 49 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 8, 2026, 5:49 PM EDT
Not yet recruiting No phase listed Observational

A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity

NCT07437976
View directory record Official record
Conditions
Obesity
Interventions
Weight loss intervention, No Weight loss intervention
Behavioral
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
5 Years to 12 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2036
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional

Sperm, Exposure and Endocrine Disruptors

NCT07703046
View directory record Official record
Conditions
Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
Interventions
EDC Education Intervention
Behavioral
Lead sponsor
Million Marker Wellness, Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Environmental Risk Factors for Myositis in Military Personnel

NCT01734369
View directory record Official record
Conditions
Dermatomyositis, Adult Polymyositis, Inclusion Body Myositis, Myositis
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
7
States / cities
Miami, Florida • Bethesda, Maryland • Research Triangle Park, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility

NCT02767973
View directory record Official record
Conditions
Airway Inflammation, Allergic Asthma
Interventions
Wood Smoke Particles (WSP)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Immune Cell Response to Stimuli

NCT00397280
View directory record Official record
Conditions
Inflammation
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 65 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 8, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Community Organizing Network for Environmental Health

NCT00042484
View directory record Official record
Conditions
Asthma
Interventions
Community-level intervention & policy change
Procedure
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Timeline
Ends 2002
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)

NCT00106652
View directory record Official record
Conditions
Autism, Developmental Disabilities
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
24 Months to 60 Months
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2017
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Oct 8, 2026, 5:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Diesel Exhaust and Vascular Function

NCT01508637
View directory record Official record
Conditions
Cardiovascular Effects
Interventions
Diesel Exhaust, Filtered Air, Terazosin, placebo
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Oct 8, 2026, 5:49 PM EDT
Completed No phase listed Observational

Qualitative Assessment of the Work-Sleep Relationship

NCT03389828
View directory record Official record
Conditions
Sleep Health
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
25 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Silver Spring, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 8, 2026, 5:49 PM EDT