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Showing 1–24 of 132 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Nemours Children's Clinic Clear all
Completed Not applicable Interventional

Transporter Mediated Uptake of Montelukast

NCT00513760
View directory record Official record
Conditions
Asthma
Interventions
Grapefruit juice, Orange Juice, Gatorade
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
15 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

NCT00139477
View directory record Official record
Conditions
Obesity
Interventions
Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
Drug · Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
7 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 1, 2026, 5:44 PM EDT
Terminated Not applicable Interventional Results available

Safety Outcomes of Vertebral Body Tethering Technique

NCT04119284
View directory record Official record
Conditions
Idiopathic Adolescent Scoliosis
Interventions
Anterior body tether (ABT)
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 16 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional Results available

Transdisciplinary Versus Usual Care for Type1 Diabetes in Adolescence

NCT03557151
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Usual Care, Transdisciplinary Care-In Person & Telehealth
Other · Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
11 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Wilmington, Delaware • Jacksonville, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 2Phase 3 Interventional

Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys

NCT00133354
View directory record Official record
Conditions
Hypopituitarism
Interventions
Arimidex (Anastrozole), Placebo, Growth Hormone
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
11 Years to 18 Years · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2011 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

MethaCholine Bronchoprovocation Study (MeCIS)

NCT00705341
View directory record Official record
Conditions
Asthma
Interventions
fluticasone
Drug
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
12 Years to 69 Years
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
13
States / cities
San Diego, California • Jacksonville, Florida • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Fish Oil Study for High Triglyceride Levels in Children

NCT00915902
View directory record Official record
Conditions
Hypertriglyceridemia
Interventions
Omega-3-acid ethyl esters, Placebo
Drug
Lead sponsor
Babu Balagopal
Other
Eligibility
10 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
3
States / cities
Wilmington, Delaware • Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Sep 1, 2026, 5:44 PM EDT
Terminated Phase 1 Interventional

Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions

NCT04172922
View directory record Official record
Conditions
Vascular Anomaly
Interventions
Topical Sirolimus
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
36 Months to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Jacksonville, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 3 Interventional

Behavior Therapy for Families of Diabetic Adolescents

NCT00358059
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Behavioral Family Systems Therapy for Diabetes
Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 16 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
2
States / cities
Jacksonville, Florida • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 27, 2006 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 2 Interventional

Antioxidant Therapy in Lean and Obese Asthmatics

NCT01317563
View directory record Official record
Conditions
Asthma
Interventions
Vitamins A, E, C & Selenium, Placebo
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 25 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2016 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Type 2 Diabetes and the Brain in Adolescents

NCT03461510
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity, Pediatric Obesity, Insulin Resistance, Dysglycemia, Hyperglycemia
Interventions
Hyperglycemic clamp, Hyperinsulinemic Euglycemic clamp
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Sep 1, 2026, 5:44 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Support Tool for Families of High-Risk Children With Heart Disease During Hospital Admission and After Discharge

NCT05926661
View directory record Official record
Conditions
Heart Disease Congenital
Interventions
NCC Support Toolkit
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional

A Crowdsourced Social Media Portal for Parents of Very Young Children With Type 1 Diabetes

NCT03222180
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Website
Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Day to 6 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional

FL3X Study: An Adaptive Intervention to Improve Outcomes for Youth With Type 1 Diabetes (FL3X)

NCT01286350
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
FL3X: Flexible Lifestyle Empowering Change
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 16 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Aurora, Colorado • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 2Phase 3 Interventional Results available

The Effects of Inhaled Nitric Oxide After Fontan Operation

NCT00945529
View directory record Official record
Conditions
Congenital Heart Defect
Interventions
inhaled nitric oxide (iNO)
Drug
Lead sponsor
Ellen Spurrier
Other
Eligibility
1 Year to 5 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 1, 2026, 5:44 PM EDT
Completed No phase listed Observational

Pharmacodynamics of CNP During Growth Hormone Treatment

NCT01504802
View directory record Official record
Conditions
Pituitary Dwarfism, Idiopathic Short Stature
Interventions
Not listed
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
3 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Los Angeles, California • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Sep 1, 2026, 5:44 PM EDT
Terminated Phase 2 Interventional

Tiotropium vs. Inhaled Corticosteroids in Children With Nonatopic Asthma Pilot Study (TioNAAP)

NCT04990167
View directory record Official record
Conditions
Asthma in Children
Interventions
Tiotropium Bromide
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Years to 11 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Ultrasound Use to Measure Magnetically Controlled Growing Rods

NCT07212049
View directory record Official record
Conditions
Limb Length Discrepancy
Interventions
ultrasound measurement, X-ray imaging of tibia and/or femur
Device · Diagnostic Test
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Phase 1 Interventional

Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis

NCT01721382
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Sitagliptin
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
13 Years to 20 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2016 · Synced Sep 1, 2026, 5:44 PM EDT
Completed No phase listed Observational

Importance of Non-Acid Reflux in Asthma in Children

NCT00200980
View directory record Official record
Conditions
Asthma, Gastroesophageal Reflux
Interventions
Not listed
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 8, 2009 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional Results available

Continuous Glucose Monitoring in Adolescents With Poorly Controlled Type 1 Diabetes

NCT01586065
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Continuous Glucose Monitor (CGM)
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Sep 1, 2026, 5:44 PM EDT
Completed No phase listed Observational

Vitamin D3 Supplementation in Pediatric IBD: Weely vs Daily Dosing Regimens

NCT02256605
View directory record Official record
Conditions
Inflammatory Bowel Disease (IBD)
Interventions
Vitamin D-3
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
5 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Sep 1, 2026, 5:44 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

NCT06406725
View directory record Official record
Conditions
Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy, Recurrent Laryngeal Nerve Injuries
Interventions
Point-of-Care Ultrasound of the Airway
Diagnostic Test
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Day to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Queens, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 1, 2026, 5:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mask Study: One-handed vs. Two Handed Technique in Children

NCT03215121
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 8 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 1, 2026, 5:44 PM EDT