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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:52 PM EST

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.

Filters: Sponsor: Primus Pharmaceuticals Clear all

Conditions: Psoriasis
Interventions: DFD06; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 6 Years to 17 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 9
States / cities: Madera, California • Santa Ana, California • Hialeah, Florida + 5 more

Conditions: Osteoarthritis
Interventions: flavocoxid, Naproxen; Dietary Supplement · Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 30 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 1
States / cities: Melbourne, Florida

Conditions: Plaque Psoriasis
Interventions: DFD-01 (betamethasone dipropionate) Spray, 0.05%; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 4
States / cities: Arlington Heights, Illinois • New Albany, Indiana • Louisville, Kentucky + 1 more

Conditions: Plaque Psoriasis
Interventions: DFD01 Spray; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 12 Years to 16 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 8
States / cities: Encino, California • Irvine, California • San Diego, California + 5 more

Conditions: Osteoarthritis
Interventions: Flavocoxid, Placebo; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 40 Years to 75 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Psoriasis
Interventions: DFD01 Spray, Comp01 Lotion, Vehicle Lotion, Vehicle Spray; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 394 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 40
States / cities: Mobile, Alabama • Hot Springs, Arkansas • Encinitas, California + 35 more

Conditions: Healthy Participant
Interventions: Metaxalone Pill, tizanidine 8 mg; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Healthy Participants
Interventions: Metaxalone m640 mg oral tablet, Metaxalone 800 mg oral tablet; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Venous Insufficiency of Leg, Venous Reflux, Varicose Veins, Lower Extremity Edema Chronic
Interventions: Vasculera, Placebo; Other
Lead sponsor: Corewell Health West; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Diabetic Ulcers
Interventions: Vasculera; Dietary Supplement
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 25 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Healthy Participants
Interventions: Metaxalone 640 mg, Metaxalone 800 MG; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Lipedema
Interventions: Diosmiplex; Dietary Supplement
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 20 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Irritant Contact Dermatitis
Interventions: EpiCeram; Device
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Peoria, Arizona

Conditions: Plaque Psoriasis
Interventions: DFD01 Spray, Comp01 Lotion; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 12
States / cities: Encinitas, California • Encino, California • Santa Rosa, California + 8 more

Conditions: Raynaud's Disease
Interventions: placebo, diosmiplex; Other · Dietary Supplement
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 11
States / cities: Peoria, Arizona • Scottsdale, Arizona • Los Alamitos, California + 8 more

Conditions: Sciatica Acute, Lumbar Spinal Stenosis
Interventions: Metaxalone 640 mg Oral Tablet; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 24
States / cities: Auburn, Alabama • Valley Village, California • Aventura, Florida + 21 more

Conditions: Osteoarthritis
Interventions: Flavocoxid 500 mg, Naproxen, Placebo, flavocoxid 250 mg; Dietary Supplement · Drug · Other
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 35 Years to 85 Years
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Duncansville, Pennsylvania

Conditions: Osteoarthritis
Interventions: Naproxen, flavocoxid 250 mg, flavocoxid 500 mg; Drug · Dietary Supplement
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 35 Years to 85 Years
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Psoriasis
Interventions: DFD01 Spray, Vehicle Spray; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 28
States / cities: Mobile, Alabama • Tempe, Arizona • Oceanside, California + 24 more

Conditions: Cognitive Impairment
Interventions: metaxalone m640 mg, tizanidine 8mg; Drug
Lead sponsor: Primus Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Peoria, Arizona

Search by objective public record fields.

Assess the Potential for Adrenal Suppression and Systemic Drug Absorption Following Multiple Dosing With DFD-06

Safety, Efficacy and Acceptability of Flavocoxid (Limbrel)A Pilot Study

Patient Satisfaction Following Twice Daily Dosing With DFD-01 in Subjects With Moderate Plaque Psoriasis

DFD01 Spray HPA Axis Suppression Study in Adolescent Patients With Moderate to Severe Plaque Psoriasis

Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis

A Comparison of DFD01 Spray Versus Comp01 Lotion, Vehicle Spray and Vehicle Lotion in Subjects With Moderate Psoriasis

Effect of Metaxalone 640 mg (M640) on Driving, Cognition, and EEG Dynamics Compared to Tizanidine 8 mg in Adults

Study to Assess Drowsiness, Cognition, Fall Risk After Metaxalone 640 mg and Metaxalone 800 mg

Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting

Safety and Efficacy of Vasculera® in the Healing of Diabetic Skin Ulcers

Testing Healthy Participants for Drowsiness After Single Dosing of Two Different Doses of Muscle Relaxer

Vasculera in Participants With Lipedema

EpiCeram for Skin Protection in Healthcare Workers

DFD01 Spray vs Comp01 Lotion HPA Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis

Diosmiplex (Vasculera®) in Primary and Secondary Raynaud's Phenomenon

Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

Study of Flavocoxid (Limbrel) Versus Naproxen in Subjects With Moderate-Severe Osteoarthritis of the Knee

Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee

A Comparison of DFD01 Spray Versus Vehicle Spray in Subjects With Moderate Psoriasis

Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition