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ClinicalTrials.gov public records Last synced Sep 27, 2026, 1:18 PM EDT

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Showing 1–8 of 8 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 1Phase 2 Interventional Results available

Study of RP-3500, Camonsertib, in Advanced Solid Tumors

NCT04497116
Conditions
Advanced Solid Tumor
Interventions
RP-3500 (camonsertib), Talazoparib, Gemcitabine Injection
Drug
Lead sponsor
Repare Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
8
States / cities
Chicago, Illinois • Boston, Massachusetts • New York, New York + 4 more
Terminated Phase 1 Interventional Results available

Study of RP-6306 With FOLFIRI in Advanced Solid Tumors

NCT05147350
Conditions
Advanced Solid Tumor
Interventions
RP-6306 (oral PKMYT1 inhibitor)
Drug
Lead sponsor
Debiopharm International SA
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Tampa, Florida • New York, New York + 2 more
Terminated Phase 1 Interventional Results available

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

NCT06232408
Conditions
Advanced Solid Tumor
Interventions
RP-1664
Drug
Lead sponsor
Repare Therapeutics
Industry
Eligibility
12 Years to 100 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
San Francisco, California • New Haven, Connecticut • New York, New York
Conditions
Advanced Solid Tumor, Adult
Interventions
RP-3500 (camonsertib)
Drug
Lead sponsor
Repare Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
13
States / cities
Phoenix, Arizona • San Francisco, California • Aurora, Colorado + 9 more
Conditions
Adult Solid Tumor
Interventions
RP-6306 (oral PKMYT1 inhibitor)
Drug
Lead sponsor
Debiopharm International SA
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Jacksonville, Florida + 5 more
Conditions
Chronic Lymphocytic Leukemia
Interventions
RP-3500, Olaparib
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Advanced Solid Tumor
Interventions
RP-3467 at assigned dose and schedule, Olaparib 200-300 mg BID, daily
Drug
Lead sponsor
Repare Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
5
States / cities
San Francisco, California • St Louis, Missouri • New York, New York + 1 more
Conditions
Solid Tumor, Metastatic Cancer
Interventions
RP-3500, External Beam Radiotherapy (EBRT)
Drug · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more