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ClinicalTrials.gov public records Last synced Oct 16, 2026, 4:41 PM EDT

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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Research Insight LLC Clear all
Completed No phase listed Observational

2311 TURGOR Study -Surgical Efficiency and Postoperative Corneal Clarity With Near Physiologic vs High IOP Settings

NCT07144644
View directory record Official record
Conditions
Intraocular Pressure
Interventions
Adjusting intraocular pressure (IOP) settings
Device
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Timeline
2024 – 2025
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 1 Interventional

Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma

NCT04787991
View directory record Official record
Conditions
Metastatic Pancreatic Adenocarcinoma
Interventions
Nivolumab (Cohort A), Ipilimumab (Cohort A, B and C), Hydroxychloroquine (HCQ) (Cohort B), Nab-paclitaxel (nP) (Cohort A, B and C), Gemcitabine (gem) (Cohort A, B and C), NG350A (Cohort C)
Drug
Lead sponsor
Cancer Insight, LLC
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The DEPOT Study (Dry Eye Prescription Options for Therapy)

NCT04911361
View directory record Official record
Conditions
Dry Eye
Interventions
Dexamethasone
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
3
States / cities
Hemet, California • Laguna Hills, California • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Cequa Treatment on Accuracy of Pre-operative Biometry & Higher Order Aberrations in Dry Eye Patients Undergoing Cataract Surgery

NCT04342988
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Cequa
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Laguna Hills, California • St Louis, Missouri • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2021 · Synced Oct 16, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction

NCT05346172
View directory record Official record
Conditions
Cataract
Interventions
PanOptix or PanOptix Toric IOL
Device
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
3
States / cities
Laguna Hills, California • Stuart, Florida • Evansville, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 16, 2026, 4:41 PM EDT
Completed No phase listed Observational

The PanOptix Trifocal IOL: A Study of Patient Satisfaction, Visual Disturbances, and Uncorrected Visual Performance

NCT04146961
View directory record Official record
Conditions
Cataract Surgery
Interventions
Alcon PanOptix or PanOptix Toric IOL
Device
Lead sponsor
Research Insight LLC
Industry
Eligibility
Not listed
Enrollment
59 participants
Timeline
2019 – 2020
U.S. locations
3
States / cities
Laguna Hills, California • Palm City, Florida • Edwardsville, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization

NCT05322148
View directory record Official record
Conditions
Dry Eye
Interventions
Klarity CL, Cylcosporine 0.1%/Loteprednol Etabonate 0.2% Preservative Free
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
3
States / cities
Hemet, California • Laguna Hills, California • Brecksville, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Pre-operative Measurements With Intraoperative Aberrometry in Predicting Correction for Low Toric Lens Correction in Cataract Surgery

NCT04247152
View directory record Official record
Conditions
Cataract Surgery
Interventions
Intraoperative Aberrometry vs preoperative biometry
Other
Lead sponsor
Research Insight LLC
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Oct 16, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Veracity Surgical: A Time/Motion and Quality of Care Study

NCT04337892
View directory record Official record
Conditions
Cataract
Interventions
Standard of Care4
Device
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 16, 2026, 4:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vivity Insight: A Study of Patient Satisfaction and Visual Performance

NCT04495049
View directory record Official record
Conditions
Cataract
Interventions
Alcon Vivity or Vivity Toric IOL
Device
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Laguna Hills, California • Palm City, Florida • Edwardsville, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 16, 2026, 4:41 PM EDT
Completed No phase listed Observational

Observational Study of C. Diff in Post-Transplant Patients

NCT02747017
View directory record Official record
Conditions
Clostridium Difficile
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
4
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The THINK Study Incidence of Neurotrophic Keratopathy)

NCT06482164
View directory record Official record
Conditions
Dry Eye
Interventions
Dry Eye Disease
Diagnostic Test
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Laguna Beach, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%

NCT04273282
View directory record Official record
Conditions
Cataract
Interventions
Dexycu intracameral dexamethasone, Prednisolone Acetate
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Laguna Hills, California • Garden City, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2020 · Synced Oct 16, 2026, 4:41 PM EDT
Not yet recruiting Phase 4 Interventional

The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)

NCT07276802
View directory record Official record
Conditions
Post Cataract Surgery
Interventions
Triamcinolone (Optional), control group
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
22 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The COAT Trial: Cequa's Onset of Action Trial

NCT06482177
View directory record Official record
Conditions
Dry Eye
Interventions
Cyclosporine ophthalmic solution
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Laguna Hills, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2024 · Synced Oct 16, 2026, 4:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study

NCT04669561
View directory record Official record
Conditions
Dry Eye
Interventions
Lifitegrast 5% Ophthalmic Solution
Drug
Lead sponsor
Research Insight LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
3
States / cities
Laguna Hills, California • Jacksonville, Florida • Brecksville, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 16, 2026, 4:41 PM EDT