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ClinicalTrials.gov public records Last synced Oct 6, 2026, 11:04 AM EDT

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Showing 1–24 of 109 matching trials from the live ClinicalTrials.gov search.
Conditions
Covid19, Pneumonia, Viral
Interventions
Prone Positioning
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Baltimore, Maryland • Chapel Hill, North Carolina • Durham, North Carolina + 1 more
Completed Not applicable Interventional Results available

Agili-C™ Implant Performance Evaluation

NCT03299959
Conditions
Cartilage or Osteochondral Defects in the Knee, Up to Moderate Osteoarthritis
Interventions
Agili-C implant, SSOC
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
11
States / cities
San Diego, California • New Orleans, Louisiana • Salisbury, Maryland + 7 more
Terminated Not applicable Interventional Results available

TRIGEN SURESHOT™ Distal Targeting System Study

NCT01327508
Conditions
Femoral Shaft Fracture
Interventions
TRIGEN SURESHOT Distal Targeting Instrumentation., Free-hand technique
Device · Other
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Sacramento, California • Gainesville, Florida • Baltimore, Maryland + 3 more
Conditions
Articular Cartilage Disorder of Knee
Interventions
Radiofrequency-Based Debridement, Mechanical Debridement
Device
Lead sponsor
Christopher Kaeding
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
ACL Reconstruction
Interventions
Bilateral hip to ankle x-ray, exam and strength testing.
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
6 Years to 16 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Chondral Lesion Plus Partial Medial Meniscectomy
Interventions
Mechanical Debridement, RF-Based Debridement
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
7
States / cities
Tucson, Arizona • Gulf Breeze, Florida • Greenwood, Indiana + 4 more
Conditions
Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears
Interventions
MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
12 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
12
States / cities
Aurora, Colorado • Colorado Springs, Colorado • Oakland Park, Florida + 9 more
Active, not recruiting No phase listed Observational

LEGION Hinge Safety and Efficacy Study

NCT02445443
Conditions
Knee Arthroplasty, Total
Interventions
LEGION Hinge Knee System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2028
U.S. locations
3
States / cities
Iowa City, Iowa • New York, New York • Portland, Oregon
Completed Not applicable Interventional Results available

Achilles Tendon Repair With Bioinductive Implant

NCT02811003
Conditions
Tendinopathy
Interventions
Rotation Medical Bioinductive Implant
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Conditions
Arthritis
Interventions
Birmingham Hip Resurfacing
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2025
U.S. locations
7
States / cities
Tucson, Arizona • Lake Charles, Louisiana • New York, New York + 4 more
Conditions
Diabetic Foot Ulcer
Interventions
Iodosorb, Solosite gel
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Conditions
Surgical Robotics, Knee Replacement
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Phoenix, Arizona • Santa Barbara, California • Battle Creek, Michigan + 2 more
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Post-traumatic Arthritis
Interventions
Ascension® MCP Finger Implant
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
9
States / cities
Tucson, Arizona • Bloomington, Indiana • Carmel, Indiana + 5 more
Conditions
Arthroplasty, Replacement, Shoulder
Interventions
Regeneten, Standard repair
Device · Procedure
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Active, not recruiting No phase listed Observational

JOURNEY II XR Safety and Effectiveness PMCF

NCT03136887
Conditions
Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis, Degenerative Arthritis Peripheral Joint, Failed Osteotomies, Failed Unicompartmental Replacement
Interventions
JOURNEY II XR Total Knee System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2029
U.S. locations
14
States / cities
Loma Linda, California • Fort Lauderdale, Florida • Aurora, Illinois + 9 more
Conditions
Suture Retention Device to Facilitate Triangular Fibrocartilage Complex (TFCC) Repair
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Miami, Florida
Completed No phase listed Observational Results available

Safety of Treatment of Shoulder Repair

NCT04552119
Conditions
Rotator Cuff
Interventions
HEALICOIL Knotless PEEK, HEALICOIL Knotless REGENESORB
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Redwood City, California • Colorado Springs, Colorado • Denver, Colorado + 2 more
Completed No phase listed Observational Accepts healthy volunteers

A Study of Patients Treated With the Journey Deuce Bicompartmental Knee System

NCT01704326
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
30 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
4
States / cities
Vero Beach, Florida • Park Ridge, Illinois • New Castle, Indiana + 1 more
Conditions
Femur Fracture
Interventions
Antegrade Intramedullary Nail, Trigen Trochanteric Femoral Nail
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Arthroplasty, Replacement, Knee
Interventions
CORI™ KNEE TENSIONER
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
New York, New York • New Albany, Ohio • Pittsburgh, Pennsylvania + 1 more
Conditions
Rheumatoid Arthritis, Degenerative Arthritis, Post Traumatic Arthritis
Interventions
Integra Cadence Total Ankle System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
9
States / cities
San Francisco, California • Sarasota, Florida • Buffalo, New York + 5 more
Conditions
Knee Dislocation
Interventions
Compass Universal Hinge External Fixator, Non-invasive External Knee Brace
Device · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2008
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Tibial Fractures
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Athens, Georgia • Fort Worth, Texas
Conditions
Non-inflammatory Degenerative Joint Disease (NIDJD) of the Knee
Interventions
Journey™ II UNI Unicompartmental Knee System
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Rockford, Illinois