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Showing 1–24 of 335 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: The Methodist Hospital Research Institute Clear all
Recruiting Not applicable Interventional

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

NCT06339320
View directory record Official record
Conditions
Endoscopic Sleeve Gastroplasty, Obesity
Interventions
Endoscopic Sleeve Gastroplasty (ESG), Apollo OverStitch endoscopic suturing device
Procedure · Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
2
States / cities
Houston, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Phase 4 Interventional

Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study

NCT06725485
View directory record Official record
Conditions
Postoperative Pain Management
Interventions
Low-Dose Lidocaine
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 1, 2026, 10:26 PM EDT
Completed No phase listed Observational

Artificial Intelligence for Digital Cholangioscopy Neoplasia Diagnosis

NCT05147389
View directory record Official record
Conditions
Common Bile Duct Neoplasms, Non-Neoplastic Bile Duct Disorder
Interventions
AI model classification, DSOC endoscopist experts' classification
Diagnostic Test
Lead sponsor
Instituto Ecuatoriano de Enfermedades Digestivas
Other
Eligibility
18 Years to 79 Years
Enrollment
170 participants
Timeline
2020 – 2022
U.S. locations
3
States / cities
New Brunswick, New Jersey • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Phase 1Phase 2 Interventional

Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL)

NCT00711035
View directory record Official record
Conditions
Adenovirus Infection, EBV Infection
Interventions
Trivirus Specific CTLs for EBV, CMV and Adenovirus Infection
Biological
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
8
States / cities
Los Angeles, California • Coral Gables, Florida • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Sep 1, 2026, 10:26 PM EDT
Terminated Not applicable Interventional

Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study

NCT06536426
View directory record Official record
Conditions
Anterior Knee Pain Syndrome
Interventions
Knee Isometric Program (KIP)
Behavioral
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 1, 2026, 10:26 PM EDT
Terminated Phase 2 Interventional Results available

Allogeneic Stem Cell Transplant for Patients With Severe Aplastic Anemia

NCT00578903
View directory record Official record
Conditions
Aplastic Anemia
Interventions
Cytoxan, Campath, Total Body Irradiation (TBI), FK-506, Methotrexate, Stem cell infusion
Drug · Radiation · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Minute to 60 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Sep 1, 2026, 10:26 PM EDT
Recruiting Phase 1 Interventional

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

NCT03740256
View directory record Official record
Conditions
Bladder Cancer, Head and Neck Squamous Cell Carcinoma, Cancer of the Salivary Gland, Lung Cancer, Breast Cancer, Gastric Cancer, Esophageal Cancer, Colorectal Cancer, Pancreatic Adenocarcinoma, Solid Tumor
Interventions
CAdVEC
Biological
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2038
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Enrolling by invitation No phase listed Observational

Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial

NCT06957236
View directory record Official record
Conditions
Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery, Robotic Surgical Procedures, Clinical Trials, Diverticulitis, Colonic, Diverticulitis Colon, Diverticulitis; Perforation, Bowel
Interventions
Not listed
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 1, 2026, 10:26 PM EDT
Not listed Not applicable Interventional

Neurostimulation of Spinal Nerves That Affect the Heart

NCT01124136
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
Neurostimulation + Medication Management (Standard of Care), Standard of Care (Control)
Device · Drug
Lead sponsor
Jerry Estep, MD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Phase 1 Interventional

Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus

NCT00880789
View directory record Official record
Conditions
Cytomegalovirus Infection, Adenovirus Infection
Interventions
CMV/AdV specific T cells
Biological
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 90 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2014 · Synced Sep 1, 2026, 10:26 PM EDT
Withdrawn Phase 1 Interventional

Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)

NCT02276820
View directory record Official record
Conditions
Adenovirus Infection
Interventions
Viralym-A
Biological
Lead sponsor
AlloVir
Industry
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced Sep 1, 2026, 10:26 PM EDT
Terminated Not applicable Interventional Results available

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

NCT03534141
View directory record Official record
Conditions
Cirrhosis, End Stage Liver Disease, Acute Kidney Injury, Liver Transplant; Complications, Chronic Kidney Diseases, Hepatitis c, Hepatitis B, NASH - Nonalcoholic Steatohepatitis, Alcoholic Cirrhosis, Hepatocellular Carcinoma
Interventions
Esophageal cooling/warming device, Mild hypothermia, Normothermia
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
3
States / cities
San Francisco, California • Aurora, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Sep 1, 2026, 10:26 PM EDT
Terminated Phase 1 Interventional

Treatment of B-CLL With Autologous IL2 and CD40 Ligand-Expressing Tumor Cells + Lenalidomide

NCT01604031
View directory record Official record
Conditions
B-cell Chronic Lymphocytic Leukemia
Interventions
B-CLL Vaccine, Lenalidomide
Biological · Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Not applicable Interventional

Radiofrequency Ablation of Atrial Fibrillation Under Apnea

NCT04170894
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Periods of Apnea, Control Arm - No Periods of Apnea
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
6
States / cities
Bay Shore, New York • Manhasset, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 1, 2026, 10:26 PM EDT
Completed No phase listed Observational

Registry for Study of Coils in Intracranial Aneurysms

NCT01000675
View directory record Official record
Conditions
Cerebral Aneurysms
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 90 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Educating Women About Pelvic Floor Disorders During Pregnancy

NCT05440539
View directory record Official record
Conditions
Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
Interventions
Written Handouts, Interactive Workshop
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 1, 2026, 10:26 PM EDT
Active, not recruiting No phase listed Observational

ROSE-Longitudinal Assessment With Neuroimaging

NCT05089331
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Chicago, Illinois • Louisville, Kentucky • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Use of Apple Vision Pro as Virtual Monitor for Diagnostic and Therapeutic Procedures

NCT07797556
View directory record Official record
Conditions
Device Convenience, Device Performance, Surgeons' Rating, Ergonomics
Interventions
Not listed
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Recruiting Phase 1Phase 2 Interventional

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

NCT03603405
View directory record Official record
Conditions
Glioblastoma, Anaplastic Astrocytoma
Interventions
ADV/HSV-tk (gene therapy)
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Terminated Phase 1Phase 2 Interventional

Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme

NCT01205334
View directory record Official record
Conditions
Glioblastoma Multiforme, GBM, Brain Cancer
Interventions
Autologous CMV-specific CTL
Biological
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2013 · Synced Sep 1, 2026, 10:26 PM EDT
Recruiting Phase 1 Interventional

Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells

NCT06798623
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Autologous Mesenchymal Stromal Cells
Biological
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Completed Not applicable Interventional

Improving Adherence to Rabies PEP Guideline Recommendations

NCT04213950
View directory record Official record
Conditions
Rabies, Rabies Human, Rabies Virus Infection
Interventions
Rabies PEP quality improvement bundle
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
15
States / cities
Baytown, Texas • Cypress, Texas • Houston, Texas + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 1, 2026, 10:26 PM EDT
Active, not recruiting No phase listed Observational

Nerve Transfer After Spinal Cord Injury- Multi-center

NCT04023591
View directory record Official record
Conditions
Tetraplegia, Spinal Cord Injuries, Quadriplegia Flaccid
Interventions
Surgery/Occupational Therapy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
7
States / cities
Stanford, California • Miami, Florida • Ann Arbor, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 1, 2026, 10:26 PM EDT
Not listed Not applicable Interventional

Hemodialysis in the Elderly (70yrs & Older)

NCT03065972
View directory record Official record
Conditions
Kidney Disease, Kidney Failure, Chronic Kidney Disease
Interventions
Surgical fistula creation from patient's anatomy, Surgical Graft implant
Procedure · Device
Lead sponsor
E. Peden, MD
Other
Eligibility
70 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 1, 2026, 10:26 PM EDT