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ClinicalTrials.gov public records Last synced Oct 8, 2026, 5:51 PM EDT

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Showing 1–4 of 4 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Topokine Therapeutics, Inc. Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study to Assess the Safety and Tolerability of TAT4 Gel in Healthy Volunteers

NCT02647853
View directory record Official record
Conditions
Nasolabial Folds, Lipoatrophy, Lipodystrophy
Interventions
TAT4 Gel concentration A, TAT4 Gel concentration B, Placebo
Drug
Lead sponsor
Topokine Therapeutics, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 8, 2026, 5:51 PM EDT
Completed Phase 2 Interventional Results available

Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)

NCT02230761
View directory record Official record
Conditions
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Interventions
XOPH5 Ointment, Placebo
Drug
Lead sponsor
Topokine Therapeutics, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 8, 2026, 5:51 PM EDT
Completed Phase 2Phase 3 Interventional

Phase 2b/3 Study of XAF5 Ointment for Steatoblepharon (Undereye Bags)

NCT02607683
View directory record Official record
Conditions
Steatoblepharon
Interventions
XAF5 (concentration A: 0.1%), XAF5 (concentration B: 0.035%), Matching placebo
Drug
Lead sponsor
Topokine Therapeutics, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
6
States / cities
Newport Beach, California • Santa Ana, California • Danbury, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 8, 2026, 5:51 PM EDT
Not listed Phase 2 Interventional

Phase 2 Study of TAT4 Gel for Reduction of Nasolabial Folds

NCT02607670
View directory record Official record
Conditions
Nasolabial Folds
Interventions
TAT4 Gel, Matching placebo
Drug
Lead sponsor
Topokine Therapeutics, Inc.
Industry
Eligibility
35 Years to 60 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2016 · Synced Oct 8, 2026, 5:51 PM EDT