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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: Truth Initiative Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Low Dose Computed Tomography for Lung Cancer Screening

NCT03084835
View directory record Official record
Conditions
Smoking
Interventions
Usual Care, WEB+TXT, WEB+TXT+TTS
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

NCT04367506
View directory record Official record
Conditions
Tobacco Cessation
Interventions
BecomeAnEX, Usual Care
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Adolescent Smoking Cessation Programs

NCT00714207
View directory record Official record
Conditions
Smoking Status
Interventions
NOT program, NOT controls, Kicking Butts intervention, KB controls
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
13 Years to 17 Years
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
8
States / cities
Baltimore, Maryland • Columbia, Maryland • Ellicott City, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2008 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Message Quit Vaping Intervention for Young Adults

NCT04251273
View directory record Official record
Conditions
Tobacco Cessation
Interventions
This is Quitting, Assessment only Control
Other
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years to 24 Years
Enrollment
2,588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation

NCT03068611
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Standard Web-based Smoking Cessation, Alcohol-focused Web-Based Smoking Cessation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Mobile Phone Support for the DC Tobacco Quitline

NCT01817842
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mobile EX cessation support, DC Quitline Support, Device Control
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
803 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2013 · Synced Sep 21, 2026, 3:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes

NCT05642715
View directory record Official record
Conditions
Hiv, Tobacco Use
Interventions
EX+, Varenicline, HR, TAU
Behavioral · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
40 Years to 79 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PROS Brief Smoking Cessation Counseling in Pediatric Practice to Reduce Secondhand Smoke Exposure of Young Children

NCT00135213
View directory record Official record
Conditions
Health Care Quality, Access, and Evaluation, Smoking Cessation
Interventions
training in smoking cessation
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2008 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Diffusion of a Smoking Cessation Application Through an Online Network

NCT01746472
View directory record Official record
Conditions
Use and Dissemination of Smoking Cessation Intervention, Cessation of Smoking
Interventions
Facebook app - condition t, Facebook app - condition z, Facebook app - condition B-active, Facebook app - condition B-passive
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
11,413 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial

NCT02997657
View directory record Official record
Conditions
Smoking Cessation
Interventions
Positive Psychotherapy, Standard smoking cessation counseling
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
271 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 21, 2026, 3:10 AM EDT
Withdrawn Not applicable Interventional

Development of a Scalable Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

NCT04340102
View directory record Official record
Conditions
Tobacco Cessation
Interventions
BecomeAnEx
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 21, 2026, 3:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lab to Real World Assessment of E-cigarette Abuse Liability and Appeal

NCT02520349
View directory record Official record
Conditions
Nicotine Dependence
Interventions
MarkTen and e-Go e-cigarettes
Device
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Text Messaging to Improve Adherence to Web-Based Cessation Treatment

NCT02585206
View directory record Official record
Conditions
Smoking Cessation
Interventions
Personalization, Integration, Dynamic Tailoring, Message Intensity, Optimal-Adherence Text
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
1,485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cessation Clinical Trial

NCT06806098
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Truth Initiative Digital Cessation Program, Usual Care
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
1,555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Results available

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

NCT01544153
View directory record Official record
Conditions
Smoking Cessation
Interventions
WEB, Social Network, Nicotine Replacement Therapy (NRT)
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
5,292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Sep 21, 2026, 3:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Young Adult Smoker's Treatment Demand

NCT01569529
View directory record Official record
Conditions
Smoking Cessation
Interventions
Online advertisement
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 30 Years
Enrollment
3,070 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Message Quit Vaping Intervention for Adolescents

NCT04919590
View directory record Official record
Conditions
Vaping, Cessation, Tobacco
Interventions
This is Quitting, Assessment only control, Waitlist control
Behavioral · Other
Lead sponsor
Truth Initiative
Other
Eligibility
13 Years to 17 Years
Enrollment
1,681 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 21, 2026, 3:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Moment Study: Mixed Method E-cigarette Study

NCT02261363
View directory record Official record
Conditions
Smoking
Interventions
Ecig group 1
Other
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 21, 2026, 3:10 AM EDT