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Showing 1–24 of 1,687 matching trials from the live ClinicalTrials.gov search.
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Filters: Sponsor: University of Minnesota Clear all
Recruiting Not applicable Interventional

Irrigating vs Traditional Negative Pressure Wound Therapy to Treat Necrotizing Soft Tissue Infections

NCT07120386
View directory record Official record
Conditions
Necrotizing Soft Tissue Infections
Interventions
Negative Pressure Wound Therapy, Negative Pressure Wound Therapy with Instillation
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting Phase 1 Interventional

Adenovirus (RGDCRAdCOX2F)

NCT06693986
View directory record Official record
Conditions
Adenocarcinoma of Pancreas
Interventions
Replicative Adenovirus Vector (RGDCRAdCOX2F)
Biological
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Adipokines Effect in Myometrial Contractility

NCT03505541
View directory record Official record
Conditions
Myometrium; Contractility, GDM, Obesity
Interventions
Adiponectin and TNFa
Biological
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Jun 7, 2026, 8:57 AM EDT
Active, not recruiting Phase 3 Interventional

Oral N-acetylcysteine for Retinitis Pigmentosa

NCT05537220
View directory record Official record
Conditions
Retinitis Pigmentosa
Interventions
N-acetylcysteine, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
24
States / cities
Davis, California • Los Angeles, California • San Francisco, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Withdrawn No phase listed Observational

Pulse Wave Analysis in Advanced Heart Failure

NCT01642927
View directory record Official record
Conditions
Left Ventricular Assist Device, Heart Failure, Intra-aortic Balloon Pump, LVAD Clot, LVAD-related GI Bleed
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Jun 7, 2026, 8:57 AM EDT
Completed Phase 1Phase 2 Interventional

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

NCT04426669
View directory record Official record
Conditions
Gastrointestinal Epithelial Cancer, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract, Cancer, Gastrointestinal, Gastrointestinal Cancer, Colo-rectal Cancer, Pancreatic Cancer, Gall Bladder Cancer, Colon Cancer, Esophageal Cancer, Stomach Cancer
Interventions
Cyclophosphamide, Fludarabine, Tumor-Infiltrating Lymphocytes (TIL), Aldesleukin
Drug · Biological
Lead sponsor
Intima Bioscience, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women

NCT04439370
View directory record Official record
Conditions
Hypertension, Menopause, Premature, Menopause, Blood Pressure
Interventions
Microneurography to measure muscle sympathetic nerve activity (MSNA), Baroreflex sensitivity testing, Sympathoexcitatory Maneuvers, Blood tests
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Terminated Phase 2 Interventional Results available

Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell Transplant

NCT00602446
View directory record Official record
Conditions
Breast Cancer, Iron Overload, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Neuroblastoma, Ovarian Cancer
Interventions
deferasirox
Drug
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 27, 2017 · Synced Jun 7, 2026, 8:57 AM EDT
Completed No phase listed Observational

Community Characteristics and Physical Activity Among Adolescent Girls - Ancillary to TAAG

NCT00046631
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases
Interventions
Not listed
Lead sponsor
RAND
Other
Eligibility
11 Years to 14 Years · Female only
Enrollment
1,556 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
6
States / cities
Tucson, Arizona • San Diego, California • New Orleans, Louisiana + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2014 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

PCS in Severe Treatment Resistant Depression

NCT04124341
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Prefrontal Cortical Stimulation (PCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Completed Phase 3 Interventional Results available

Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD)

NCT00880919
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
quetiapine extended-release, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Iowa City, Iowa • Belmont, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Jun 7, 2026, 8:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effects of Transcranial Focused Ultrasound on Human Motor Learning

NCT03130647
View directory record Official record
Conditions
Healthy
Interventions
Focused ultrasound
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Technical Development of Multi-Parametric Renocerebral MRI

NCT02831335
View directory record Official record
Conditions
Aging
Interventions
MRI, Group 4
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jun 7, 2026, 8:57 AM EDT
Withdrawn Phase 2 Interventional

Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone

NCT04325802
View directory record Official record
Conditions
Atopic Dermatitis, Pruritus, Pruritus Chronic, Dermatitis
Interventions
Naltrexone, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Jun 7, 2026, 8:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stress Reactivity as a Determinant in Co-occurring Alcohol Use and Anxiety Disorder: Diagnosis and Alcohol Use Outcomes

NCT03056872
View directory record Official record
Conditions
Alcohol Use Disorder, Anxiety Disorder/Anxiety State, Stress Disorder, Hypothalamic Pituitary Adrenal, Drinking to Cope
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Jun 7, 2026, 8:57 AM EDT
Completed Phase 3 Interventional

Alfuzosin Hydrochloride to Relieve Ureteral Stent Discomfort

NCT00467467
View directory record Official record
Conditions
Ureteral Stent Discomfort
Interventions
Alfuzosin Hydrochloride
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

NCT06957067
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Jun 7, 2026, 8:57 AM EDT
Completed Phase 2 Interventional Results available

N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers

NCT00967005
View directory record Official record
Conditions
Gambling, Tobacco Use Disorder
Interventions
N Acetyl Cysteine, Sugar Pill
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Jun 7, 2026, 8:57 AM EDT
Completed No phase listed Observational

Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer

NCT01089803
View directory record Official record
Conditions
Squamous Cell Carcinoma, Laryngeal Cancer
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

Self-Weighing for Adolescents Seeking Obesity Treatment

NCT04837586
View directory record Official record
Conditions
Adolescent Obesity
Interventions
Standard Care, Simple Scale, EHR-Connected Scale
Other · Device
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jun 7, 2026, 8:57 AM EDT
Recruiting Not applicable Interventional

Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

NCT05652153
View directory record Official record
Conditions
Suicidal Behavior, Suicidal Ideation, Negative Urgency, Cortical Inhibition, Depression
Interventions
Single-/paired-pulse transcranial magnetic stimulation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Jun 7, 2026, 8:57 AM EDT
Completed Not applicable Interventional Results available

Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS

NCT02463773
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Acute Respiratory Failure
Interventions
Ultrasound
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jun 7, 2026, 8:57 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Stem Cell Transplantation for Hematological Malignancies

NCT00176839
View directory record Official record
Conditions
Leukemia, Lymphocytic, Acute, AML, MDS
Interventions
Stem Cell Transplant, Busulfan, Cyclophosphamide, Melphalan, G-CSF, ATG
Procedure · Drug
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
Up to 35 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2017 · Synced Jun 7, 2026, 8:57 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors

NCT01196936
View directory record Official record
Conditions
Breast Cancer
Interventions
Tamoxifen Citrate, Placebo, Digital mammography, immunohistochemistry staining method, pharmacological study, laboratory biomarker analysis, protein expression analysis, pharmacogenomic studies, questionnaire administration, Fine needle aspiration, Quality of Life Assessment
Drug · Procedure · Other + 1 more
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2028
U.S. locations
12
States / cities
Birmingham, Alabama • Duarte, California • Aurora, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2026 · Synced Jun 7, 2026, 8:57 AM EDT