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ClinicalTrials.gov public records Last synced Oct 4, 2026, 2:38 AM EDT

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Showing 1–24 of 996 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: University of Southern California Clear all
Completed Phase 2 Interventional

Does Reducing Spasticity Permit an Increase in Strength?

NCT00255073
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
baclofen
Drug
Lead sponsor
University of Southern California
Other
Eligibility
5 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 23, 2014 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride

NCT03770286
View directory record Official record
Conditions
Dental Caries in Children, Dental Caries Class II, Dental Caries
Interventions
5% Fluoride Varnish, 38% Silver diamine fluoride, Super Floss
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
3 Years to 12 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 4, 2026, 2:38 AM EDT
Completed No phase listed Observational

Reducing the Duration of Untreated Psychosis

NCT03102151
View directory record Official record
Conditions
First Episode Psychosis
Interventions
Community Campaign La CLAVE
Other
Lead sponsor
University of Southern California
Other
Eligibility
15 Years to 65 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Granada Hills, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Not applicable Interventional Results available

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety (AESOPS): R21 Pilot Phase

NCT03773484
View directory record Official record
Conditions
Opioid Use, Unspecified
Interventions
Opioid naive, At-risk for long term use, Long-term opioid recipient
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

The HJ MILE HIV Prevention Intervention for Post-incarcerated Men

NCT01427543
View directory record Official record
Conditions
HIV, Risk Reduction Behavior
Interventions
MILE intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Male only
Enrollment
212 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 4, 2026, 2:38 AM EDT
Not listed No phase listed Observational

Trial of Strategies to Communicate Genetic Information to Different Ethnic Subpopulations

NCT03023735
View directory record Official record
Conditions
Communication
Interventions
None. This is an observational study
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
597 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 4, 2026, 2:38 AM EDT
Terminated Not applicable Interventional

Oral Carnitine for Cramps in Pregnancy

NCT00516516
View directory record Official record
Conditions
Muscle Cramp
Interventions
L-Carnitine, Placebo
Dietary Supplement
Lead sponsor
University of Southern California
Other
Eligibility
16 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 4, 2026, 2:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Papillary Balloon Dilation Versus Intraductal Lithotripsy

NCT03536247
View directory record Official record
Conditions
Choledocholithiasis
Interventions
Initial therapy with papillary balloon dilation, Initial therapy with intraductal lithotripsy
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 115 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 1Phase 2 Interventional

Ankle Sprains and Corticospinal Excitability

NCT00847769
View directory record Official record
Conditions
Ankle Sprain
Interventions
High velocity, low amplitude stretch, Slow, mobilization stretch, Passive Positioning
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis

NCT03208166
View directory record Official record
Conditions
Intracranial Atherosclerosis
Interventions
Doctormate, Usual Care
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
30 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 4, 2026, 2:38 AM EDT
Recruiting Phase 1Phase 2 Interventional

Topical Imiquimod Treatment of Oral Dysplasia

NCT07210775
View directory record Official record
Conditions
Oral Dysplasia, Leukoplakia Oral, Leukoplakia
Interventions
Imiquimod (topical use)
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 4 Interventional Results available

Pharmacokinetics of Omadacycline in Cystic Fibrosis

NCT04460586
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Omadacycline Injection [Nuzyra], Omadacycline Oral Tablet [Nuzyra]
Drug
Lead sponsor
Paul Beringer
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Brain Aging in Vietnam War Veterans

NCT01687153
View directory record Official record
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 90 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
19
States / cities
Sun City, Arizona • Irvine, California • La Jolla, California + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2021 · Synced Oct 4, 2026, 2:38 AM EDT
Recruiting Phase 3 Interventional

Statins In Intracerbral Hemorrhage

NCT03936361
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Statins
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
50 Years and older
Enrollment
1,456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 4 Interventional

Comparison of Systane Free vs. Saline in the Treatment of Dry Eye

NCT00388791
View directory record Official record
Conditions
Dry Eye
Interventions
Systane Free
Drug
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Oct 4, 2026, 2:38 AM EDT
Not yet recruiting Not applicable Interventional

Executive Function Play Opportunities for Children With Down Syndrome

NCT07792382
View directory record Official record
Conditions
Down Syndrome, Trisomy 21
Interventions
EXPO, EXPO Extended, EXPO Foundations
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
36 Months to 72 Months
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Not applicable Interventional

Telemedicine Monitoring of Nocturnal Incidents

NCT04328896
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Hypoglycemia
Interventions
CGM-Tele-monitoring
Other
Lead sponsor
University of Southern California
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Oct 4, 2026, 2:38 AM EDT
Withdrawn No phase listed Observational

Magnetic Resonance Imaging in Obstructive Sleep Apnea

NCT02207127
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
MRI, DISE, and Surgery
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 2 Interventional Results available

Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...

NCT01229150
View directory record Official record
Conditions
Non Small Cell Lung Carcinoma
Interventions
AZD6244, Erlotinib, AZD6244 + Erlotinib
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
5
States / cities
Davis, California • Los Angeles, California • South Pasadena, California + 2 more
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Oct 4, 2026, 2:38 AM EDT
Completed Phase 2 Interventional Results available

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

NCT03049618
View directory record Official record
Conditions
ALK Gene Mutation, BRAF Gene Mutation, EGFR Gene Mutation, Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Carcinoma, Recurrent Head and Neck Carcinoma, Recurrent Non-Small Cell Lung Carcinoma, ROS1 Gene Mutation, Stage III Non-Small Cell Lung Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung Cancer
Interventions
Laboratory Biomarker Analysis, Pembrolizumab, Recombinant EphB4-HSA Fusion Protein
Other · Biological
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 4, 2026, 2:38 AM EDT
Withdrawn Not applicable Interventional

Physical Activity in Reducing Metabolic Dysregulation (MetD) in Obese Latina Breast Cancer Survivors

NCT03120390
View directory record Official record
Conditions
Cancer Survivor, Central Obesity, No Evidence of Disease
Interventions
Best Practice, Exercise Intervention, Laboratory Biomarker Analysis, Monitoring Device, Quality-of-Life Assessment, Questionnaire Administration
Other · Behavioral · Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 4, 2026, 2:38 AM EDT
Active, not recruiting No phase listed Observational

Liver Cirrhosis Network Cohort Study

NCT05740358
View directory record Official record
Conditions
Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced, Cirrhosis Infectious, Cirrhosis Alcoholic, Cirrhosis, Biliary, Cirrhosis Cryptogenic, Cirrhosis Due to Hepatitis C, Cirrhosis Due to Primary Sclerosing Cholangitis, Autoimmune Hepatitis
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
1,222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
14
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Recruiting No phase listed Observational

Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone

NCT04097158
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Sample Collection
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 4, 2026, 2:38 AM EDT
Withdrawn Phase 1Phase 2 Interventional

MM-398 and Ramucirumab in Treating Patients With Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

NCT03739801
View directory record Official record
Conditions
Locally Advanced Unresectable Gastric Adenocarcinoma, Metastatic Gastroesophageal Junction Adenocarcinoma, Metastatic Unresectable Gastric Adenocarcinoma, Unresectable Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Interventions
Liposomal Irinotecan, Quality-of-Life Assessment, Questionnaire Administration, Ramucirumab
Drug · Other · Biological
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2020 · Synced Oct 4, 2026, 2:38 AM EDT