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ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:03 PM EDT

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Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: William Stoops Clear all
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs (Inpatient): 38

NCT03954938
View directory record Official record
Conditions
Cocaine Use, Unspecified
Interventions
Craving Manipulation, Cocaine, Placebo
Behavioral · Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 28, 2026, 11:03 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Suvorexant and Alcohol

NCT06326684
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol, Placebo, Suvorexant
Drug
Lead sponsor
William Stoops
Other
Eligibility
21 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Buspirone Maintenance on the Reinforcing Effects of Cocaine

NCT01639157
View directory record Official record
Conditions
Cocaine Use Disorders
Interventions
Buspirone, Placebo
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 19, 2016 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Cocaine and Zolmitriptan

NCT05019430
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Cocaine, Placebo oral capsule, Zolmitriptan
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Reinforcing Effects of Cocaine During Phendimetrazine Maintenance

NCT02522325
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Phendimetrazine, Cocaine, Placebo
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 2, 2019 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cocaine Use Reduction and Health

NCT03224546
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Contingency Management
Behavioral
Lead sponsor
William Stoops
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Suvorexant and Cocaine

NCT03937986
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Suvorexant, Cocaine, Placebo oral capsule
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Oct 28, 2026, 11:03 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Cocaine and Pentoxifylline (BED IN 47)

NCT07086794
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Placebo, Cocaine (IV), Pentoxifylline
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Influence of n-Acetylcysteine Maintenance on Alcohol Effects

NCT03216954
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol, Placebos, N-acetyl cysteine
Drug
Lead sponsor
William Stoops
Other
Eligibility
21 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 28, 2026, 11:03 PM EDT
Recruiting Early Phase 1 Interventional

Methamphetamine and Troriluzole

NCT06989853
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
Placebo, Methamphetamine
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

NCT05610072
View directory record Official record
Conditions
Cocaine Use Disorder, Opioid Use Disorder, Stimulant Use Disorder
Interventions
n-acetylcysteine, Hydromorphone, Placebo n-acetylcystine, Placebo hydromorphone
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 28, 2026, 11:03 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Phendimetrazine and Cocaine

NCT02233647
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Cocaine, Placebo
Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Oct 28, 2026, 11:03 PM EDT
Recruiting Not applicable Interventional

Non-Abstinence Outcomes in Methamphetamine Use Disorder

NCT07226596
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
Contingency Management
Behavioral
Lead sponsor
William Stoops
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 11:03 PM EDT