- Conditions
- Cardiogenic Shock
- Interventions
- Istaroxime, Placebo
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 1–14
of 14
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Cardiogenic Shock
- Interventions
- Istaroxime, Placebo
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Portland, Oregon
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Lucinactant delivered via investigational delivery device, nCPAP
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 26 Weeks to 32 Weeks
- Enrollment
- 221 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 22
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • Loma Linda, California + 18 more
- Conditions
- Acute Hypoxemic Respiratory Failure
- Interventions
- Lucinactant, Sham Comparator
- Drug · Other
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- Up to 2 Years
- Enrollment
- 165 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- Warrington, Pennsylvania
- Conditions
- Respiratory Distress Syndrome
- Interventions
- PSV+VG mode versus SIMV+VG mode
- Procedure
- Lead sponsor
- Children's Hospitals and Clinics of Minnesota
- Other
- Eligibility
- 72 Hours to 120 Hours
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- COVID-19, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
- Interventions
- Lucinactant
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 7
- States / cities
- La Jolla, California • San Diego, California • Augusta, Georgia + 3 more
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Aerosolized lucinactant
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 15 Minutes to 30 Minutes
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Lucinactant for inhalation, nCPAP alone
- Combination Product · Device
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 26 Weeks to 28 Weeks
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 10
- States / cities
- Loma Linda, California • San Diego, California • Newark, Delaware + 7 more
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Lucinactant for Inhalation, nCPAP alone
- Drug · Device
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 29 Weeks to 34 Weeks
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 11
- States / cities
- Birmingham, Alabama • Little Rock, Arkansas • Loma Linda, California + 8 more
- Conditions
- Solid Tumor, TNBC - Triple-Negative Breast Cancer, Hormone Receptor-positive Breast Cancer, Epithelial Ovarian Cancer, Endometrial Cancer, Cutaneous Melanoma, Thyroid Cancer, Small-cell Lung Cancer, Prostate Cancer, SORT1+ Cancers
- Interventions
- TH1902
- Drug
- Lead sponsor
- Theratechnologies
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 5
- States / cities
- Detroit, Michigan • Grand Rapids, Michigan • Gettysburg, Pennsylvania + 2 more
- Conditions
- Meconium Aspiration
- Interventions
- Lucinactant, Standard Care
- Drug · Other
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- Up to 48 Hours
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2004
- U.S. locations
- 1
- States / cities
- Warrington, Pennsylvania
- Conditions
- Respiratory Distress Syndrome, Newborn, Premature Birth, Bronchopulmonary Dysplasia
- Interventions
- Lucinactant 175 mg/kg, Lucinactant 90 mg/kg, Placebo
- Drug
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 3 Days to 10 Days
- Enrollment
- 136 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- Warrington, Pennsylvania
- Conditions
- Cystic Fibrosis
- Interventions
- Lucinactant first, Placebo first
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Acute Respiratory Distress Syndrome
- Interventions
- A.1 Lucinactant, B.3 SoC, A.2 Lucinactant, A.3 Lucinactant, A.4 Lucinactant, B.1 Lucinactant, B.2 Lucinactant
- Drug · Other
- Lead sponsor
- Windtree Therapeutics
- Industry
- Eligibility
- 16 Years to 75 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 1
- States / cities
- Warrington, Pennsylvania