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ClinicalTrials.gov public records Last synced Oct 6, 2026, 8:09 PM EDT

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
Filters: Sponsor: Zeltiq Aesthetics Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multiple CoolSculpting Treatment Study

NCT01814007
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
3
States / cities
Pleasanton, California • Walnut Creek, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pilot Clinical Trial Investigating the Effect of Cutaneous Cooling on Sebum Production

NCT01686841
View directory record Official record
Conditions
Acne
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 25 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting System

NCT04506307
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Marina del Rey, California • Pleasanton, California • Vista, California + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting and EMS for the Abdomen

NCT03738891
View directory record Official record
Conditions
Body Fat Disorder
Interventions
Zeltiq CoolSculpting System alone, Electromagnetic Muscle Stimulation alone, EMS followed by CoolSculping, CoolSculpting followed by EMS
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
4
States / cities
Marina del Rey, California • Pleasanton, California • Sacramento, California + 1 more
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Reduction of Fat in the Inner Thighs

NCT01517659
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
3
States / cities
Sacramento, California • Edina, Minnesota • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tissue Optimization on Cryolipolysis Procedures for Fat Layer Reduction

NCT01728857
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study of a Belt Applicator

NCT01767142
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System with Modified Belt Applicator
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Marina del Rey, California • Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study on the Submental Area

NCT01859091
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting in the Abdomen Using Applicator With and Without CCI

NCT02787850
View directory record Official record
Conditions
Body Fat Disorder
Interventions
CoolSculpting Treatment
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bilateral; Flank Study With Crown Cooling Insert

NCT02554760
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Phase 4 Interventional Results available

A Study to Assess the Adverse Events and Effectiveness of Rapid Acoustic Pulse (RAP) Device in Adult Participants for the Appearance of Cellulite

NCT05730335
View directory record Official record
Conditions
Cellulite
Interventions
Rapid Acoustic Pulse
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 50 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Chicago, Illinois • Nashua, New Hampshire • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Magnetic Muscle Stimulation of Abdominal Muscle

NCT04199312
View directory record Official record
Conditions
Muscle Weakness
Interventions
Magnetic Muscle Stimulation (MMS) device
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Pleasanton, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Phase 4 Interventional Results available

A Study to Assess the Adverse Events and Effectiveness of Rapid Acoustic Pulse (RAP) Device for the Appearance of Cellulite in Adult Participants

NCT05664581
View directory record Official record
Conditions
Cellulite
Interventions
Rapid Acoustic Pulse
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fat Reduction in the Submandibular/Submental Area

NCT02700165
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-invasive Cooling of Subcutaneous Fat

NCT00762307
View directory record Official record
Conditions
Fat Disorder
Interventions
Zeltiq Dermal Cooling Device
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
4
States / cities
Dublin, California • Fremont, California • Pleasanton, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Analysis of CoolSculpting by Zeltiq for Non-Invasive Cooling of Abdominal Fat Using the eZ App Large Applicator

NCT01318343
View directory record Official record
Conditions
Abdominal Fat, Adipose Tissue, Abdominal
Interventions
Not listed
Lead sponsor
Laser and Skin Surgery Center of New York
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting of the Distal Thigh Study

NCT02335749
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
4
States / cities
Miami, Florida • Chestnut Hill, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DualSculpting the Abdomen Using CoolSculpting

NCT02941146
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-Invasive Cooling of Fat Cells

NCT00762437
View directory record Official record
Conditions
Reduction of Unwanted Fat
Interventions
Zeltiq Dermal Cooling Device
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
11
States / cities
Sacramento, California • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Subcutaneous Fat Reduction in the Submental Area

NCT02298322
View directory record Official record
Conditions
Body Fat Disorder
Interventions
CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
3
States / cities
Sacramento, California • Edina, Minnesota • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fat Layer Reduction in the Lateral Thighs Using CoolSculpting

NCT02324816
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cyrolipolysis vs Cyrolipolysis and Subcision for Cellulite

NCT02427698
View directory record Official record
Conditions
Cellulite
Interventions
cyrolipolysis (CoolSculpting device), subcision
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting of the Flank With Alternate Treatment Parameters

NCT02081196
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The Zeltiq CoolSculpting System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
2
States / cities
Sacramento, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Oct 6, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CoolSculpting and RF for the Submental

NCT03873779
View directory record Official record
Conditions
Body Fat Disorder
Interventions
The ZELTIQ System
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
22 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 6, 2026, 8:09 PM EDT