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Yale University clinical trials

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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:44 PM EDT

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Yale University
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Showing 337–348 of 1,897 matching trials for sponsor Yale University.
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Recruiting Phase 1 Interventional

Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy

NCT05989347
View directory record Official record
Conditions
Breast Cancer, Hyperinsulinism, HER2-negative Breast Cancer
Interventions
Dapagliflozin 10mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Phase 1 Interventional

Mechanisms of Diuretic Resistance in Heart Failure, Aim 3

NCT06209359
View directory record Official record
Conditions
Heart Failure, Diuretic Resistance
Interventions
Ammonium Chloride, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Saci Nivo Rela for TNBC

NCT06963905
View directory record Official record
Conditions
Metastatic Triple-negative Breast Cancer
Interventions
Relatlimab FDC + Nivolumab, Sacituzumab Govitecan (SG), Nivolumab
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Phase 1 Interventional

Mechanisms of Diuretic Resistance in Heart Failure, Aim 1

NCT05323487
View directory record Official record
Conditions
Heart Failure
Interventions
Bumetanide Injection
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Developing a Novel Human Laboratory Paradigm for AUD Medication Screening

NCT06489782
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Model 1, Model 2
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Phase 2 Interventional

Substance Misuse and Family Violence Treatment Fathers

NCT06650267
View directory record Official record
Conditions
Substance Misuse, Violence, Domestic, Child Abuse
Interventions
Fathers for Change (F4C), Individual Drug Counseling (IDC)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery

NCT06474754
View directory record Official record
Conditions
Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period
Interventions
High-sensitivity troponin, serum, Submaximal Cardiopulmonary Exercise Testing, Duke Activity Status Index
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
45 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Not applicable Interventional

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

NCT05551325
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
Interventions
Chronobundle - light, chronobundle - feeding, chronobundle - mobility, chronobundle - sleep
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting Not applicable Interventional

Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

NCT06094478
View directory record Official record
Conditions
Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
Interventions
HI-SPEED Protocol
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
8
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Withdrawn Phase 1 Interventional

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

NCT03752918
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
MDMA, Niacin
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Recruiting No phase listed Observational

An Evaluation of Hip Preservation Outcomes

NCT05746533
View directory record Official record
Conditions
Hip Arthroscopy, Femoroacetabular Impingement
Interventions
Hip Arthroscopy
Procedure
Lead sponsor
Yale University
Other
Eligibility
12 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2053
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 20, 2026, 1:44 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM

NCT06661343
View directory record Official record
Conditions
HIV Prevention
Interventions
C4 Program, C4 + 3MV Program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
New York, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 20, 2026, 1:44 PM EDT

About this Yale University sponsor directory page

What this page lists
U.S. ClinicalTrials.gov public records where Yale University is the lead sponsor, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results
Use the filters above to scope by condition, intervention, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Yale University trials.
Where the data comes from
Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do
No medical advice, eligibility judgments, sponsor quality scoring, ranking of trials, or AI-generated medical summaries.

Related: all sponsor pages, browse by condition, browse by drug or therapy, browse by U.S. city, trials at Yale in New Haven, CT, or open the full search for Yale University.