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Completed Phase 3 Interventional

Evaluation of Galantamine in the Treatment of Alzheimer's Disease

ClinicalTrials.gov ID: NCT00000172

Public ClinicalTrials.gov record NCT00000172. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:39 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Placebo Controlled Evaluation of Galantamine in the Treatment of Alzheimer's Disease: Safety and Efficacy Under a Slow-Titration Regimen

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Galantamine is an experimental drug being evaluated in the United States for the treatment of Alzheimer's disease. Results from previous clinical trials suggest that galantamine may improve cognitive performance in individuals with Alzheimer's disease. It is not a cure for Alzheimer's disease. Nerve cells in the brain responsible for memory and cognitive function communicate using a chemical called acetylcholine. Research has shown that deterioration of cells that produce acetylcholine in the brain affects thought processes. Galantamine is thought to work in two ways to increase the amount of acetylcholine available in the brain. It inhibits an enzyme that breaks down acetylcholine and it also stimulates the nicotinic receptors in the brain to release more acetylcholine.

Study identification

NCT ID
NCT00000172
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Janssen, LP
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
0 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
Jun 24, 2005

United States locations

U.S. sites
55
U.S. states
26
U.S. cities
50
Facility City State ZIP Site status
University of Alabama, Birmingham Birmingham Alabama 35294-0017 —
James L. Frey, M.D., Ltd. Scottsdale Arizona 85258 —
East Bay Neurology Berkeley California 94705 —
University of Southern California Los Angeles California 90033-1039 —
N. County Neurology Assoc. Oceanside California 92056 —
University of California Irvine Medical Center Orange California 92868 —
Pacific Research Network (PRN) San Diego California 92103 —
Affiliated Research Institute San Diego California 92108 —
INC San Diego California 92122 —
The Denver Center for Medical Research Denver Colorado 80212 —
Geriatric and Adult Psychiatry Hamden Connecticut 06518 —
Yale University, School of Medicine New Haven Connecticut 06520 —
Ocala Neurodiagnostic Center Ocala Florida 34471 —
Psychiatric Institute of Florida Orlando Florida 32806 —
Neurological Research Institute of Sarasota, PA Sarasota Florida 34239 —
Suncoast Neuroscience Associates, Inc. St. Petersburg Florida 33701 —
Premiere Research Institute West Palm Beach Florida 33407 —
Chicago Center for Clinical Research Chicago Illinois 606104234 —
OSF Center for Senior Health Peoria Illinois 616033089 —
Indiana Alzheimer's University Clinic Indianapolis Indiana 46202-5111 —
The Johns Hopkins Hospital Baltimore Maryland 21287 —
Brigham Behavioral Neurology Group Boston Massachusetts 02115 —
Boston Clinical Research Center Wellesley Hills Massachusetts 02481 —
University of Massachusetts Worcester Worcester Massachusetts 01655 —
Oakwood Hospital and Medical Center Dearborn Michigan 48124 —
Michigan Medical P.C. Grand Rapids Michigan 49503 —
Regions Hospital Saint Paul Minnesota 55101 —
St. Louis University School of Medicine St Louis Missouri 63104 —
Washington University St Louis Missouri 63108 —
University of Nebraska Omaha Nebraska 681985575 —
University of Medicine and Dentistry of New Jersey Piscataway New Jersey 088551392 —
Neurology Group of Bergen County Ridgewood New Jersey 07450 —
Overlook Hospital Summit New Jersey 07901 —
Medwise Center West Long Branch New Jersey 07764 —
Neurological Associates of Albany, PC Albany New York 12208 —
East End Neuropsychiatric Associates Centereach New York 11720 —
St. John's Episcopal Hospital Far Rockaway New York 11691 —
NYU Medical Center New York New York 10016 —
University of Rochester Rochester New York 14620 —
SUNY Stony Brook Stony Brook New York 11794-8121 —
Ohio State University Columbus Ohio 43210 —
Clinical Pharmaceutical Trials Tulsa Oklahoma 741025428 —
Oregon Health Sciences University Portland Oregon 97201-3098 —
Pacific NW Clinical Research Center Portland Oregon 97201 —
Institute for Advanced Clinical Research Elkins Park Pennsylvania 19027 —
Neuroscience Center of Westmoreland Neurology Greensburg Pennsylvania 15601 —
Brown University Pawtucket Rhode Island 02906 —
Alzheimer's Research and Clinical Programs North Charleston South Carolina 294066076 —
University of Texas Dallas Texas 752359070 —
Southwestern Vermont Medical Center Bennington Vermont 05201 —
Memory Disorder Center of Vermont Colchester Vermont 05446 —
Virginia Neuroscience Center Alexandria Virginia 22304 —
Prince William Neuroscience Center Manassas Virginia 20010 —
Seattle Clinical Research Center Seattle Washington 98104 —
VAPS Health Care System Seattle Washington 98108 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000172, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 24, 2005 · Synced Oct 28, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00000172 live on ClinicalTrials.gov.

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