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ClinicalTrials.gov record
Completed Phase 3 Interventional

Estrogen Hormone Protocol

ClinicalTrials.gov ID: NCT00000177

Public ClinicalTrials.gov record NCT00000177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 11:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Estrogen is a hormone that is dominant in the female reproductive system. In women, most estrogen is produced by the ovaries. Men produce estrogen by converting testosterone into estrogen. Because this hormone also has many beneficial effects on brain cells, it currently is being studied as a treatment for Alzheimer's disease. The enzyme that forms the neurotransmitter acetylcholine is promoted in the presence of estrogen. Several very small clinical studies have demonstrated improvement in cognitive function and mood measures in women with Alzheimer's disease who take estrogen.

Study identification

NCT ID
NCT00000177
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
120 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
60 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 1995 (Type not available)
Primary completion
Jan 1999 (Actual)
Completion
Jan 1999 (Actual)
Last update posted
Dec 11, 2009

1995 – 1999

United States locations

U.S. sites
25
U.S. states
17
U.S. cities
23
Facility City State ZIP Site status
University of Alabama, Birmingham Birmingham Alabama 35294-0017 —
University of California, San Diego San Diego California 92093 —
Mayo Clinic Jacksonville Jacksonville Florida 32225 —
University of South Florida Tampa Florida — —
Emory University Atlanta Georgia 30329 —
Rush Presbyterian St. Luke's Medical Center Chicago Illinois 60612 —
Southern Illinois University Springfield Illinois 62702 —
Indiana University Medical Center Indianapolis Indiana 46202-5266 —
University of Kansas Medical Center Kansas City Kansas 66160 —
University of Kentucky Lexington Kentucky 40536-0230 —
Johns Hopkins University Baltimore Maryland 21224 —
Massachusetts General Hospital Boston Massachusetts 02114 —
University of Minnesota Minneapolis Minnesota 55455 —
Mayo Clinic Rochester Minnesota 55901-0144 —
Washington University St Louis Missouri 63110 —
New York University Medical Center New York New York 10016 —
Mount Sinai School of Medicine New York New York 10029 —
Columbia Presbyterian Medical Center New York New York 11032 —
Burke Medical Research Institute White Plains New York 10605 —
University Hospitals of Cleveland Cleveland Ohio 44120 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
University of Pittsburgh Pittsburgh Pennsylvania 15213 —
University of Texas Dallas Texas 75235 —
Baylor College of Medicine Houston Texas 77030 —
University of Washington Seattle Washington 98195 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 11, 2009 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00000177 live on ClinicalTrials.gov.

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