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Completed Phase 3 Interventional

Agitation in Alzheimer's Disease

ClinicalTrials.gov ID: NCT00000179

Public ClinicalTrials.gov record NCT00000179. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Agitation affects 70 to 90 percent of patients with AD. Signs of agitation include verbal and physical aggressiveness, irritability, wandering, and restlessness. These behaviors often make caring for patients at home very difficult. Trazodone and haldol are two of the most commonly prescribed drugs for agitation in AD patients. Behavior management, a non drug approach, has been effective in reducing signs of agitation. Researchers have yet to compare the effectiveness of drug versus non drug therapy to treat agitation in AD patients and determine which is the best treatment. The Alzheimer's Disease Cooperative Study, with funding from the National Institute on Aging, is conducting an agitation treatment program at 21 sites in 16 States. This study will assess which of the above treatments is most effective.

Study identification

NCT ID
NCT00000179
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
Not listed

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
Jun 23, 2005

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
University of California, Los Angeles Los Angeles California 90095
University of California, San Diego San Diego California 92093-0949
University of Miami Miami Florida 33140
University of South Florida Tampa Florida 33162
Emory University Atlanta Georgia 30329
Southern Illinois University Springfield Illinois 62702
University of Kansas Medical Center Kansas City Kansas 66160
University of Kentucky Lexington Kentucky 40536
University of Massachusetts Worcester Massachusetts 01665
University of Michigan Ann Arbor Michigan 48109
University of Minnesota Minneapolis Minnesota 55455
New York University Medical Center New York New York 10016
Mount Sinai Medical Center New York New York 10029
University of Rochester Rochester New York 14620
University Hospitals of Cleveland Cleveland Ohio 44120
Oregon Health Sciences University Portland Oregon 97201-3098

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000179, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 23, 2005 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00000179 live on ClinicalTrials.gov.

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