A Pilot Study Evaluating Penicillin G and Ceftriaxone as Therapies for Presumed Neurosyphilis in HIV Seropositive Individuals
Public ClinicalTrials.gov record NCT00000648. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To provide information on the response of HIV infected, neurosyphilis patients to the currently recommended treatment for neurosyphilis; to determine whether possible co-infection with both HIV and syphilis makes more difficult the diagnosis of syphilis; to explore the usefulness of an alternative treatment which, if effective, would permit outpatient treatment for neurosyphilis that until now required prolonged hospitalization. Studies suggest that syphilis treatment failures may be more common in HIV infected patients than in patients without HIV infection and that treatment failures occur due to and/or are displayed as central nervous system (CNS) involvement. Very little is known about the best treatment course for neurosyphilis in patients who are also infected with HIV.
Study identification
- NCT ID
- NCT00000648
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Feb 1996 (Actual)
- Last update posted
- Oct 27, 2021
Ends 1996
United States locations
- U.S. sites
- 42
- U.S. states
- 15
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Univ of California / San Diego Treatment Ctr | San Diego | California | 921036325 | — |
| San Francisco Veterans Administration Med Ctr | San Francisco | California | 94121 | — |
| Harbor UCLA Med Ctr | Torrance | California | 90502 | — |
| Yale Univ / New Haven | New Haven | Connecticut | 065102483 | — |
| Florida Keys Memorial Hosp | Key West | Florida | 33040 | — |
| Med Service | Miami | Florida | 33125 | — |
| Miami Veterans Administration Med Ctr | Miami | Florida | 33125 | — |
| Univ of Miami School of Medicine | Miami | Florida | 33136 | — |
| Northwestern Univ Med School | Chicago | Illinois | 60611 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Indiana Univ Hosp | Indianapolis | Indiana | 462025250 | — |
| Methodist Hosp of Indiana / Life Care Clinic | Indianapolis | Indiana | 46202 | — |
| Johns Hopkins Hosp | Baltimore | Maryland | 21287 | — |
| Beth Israel Deaconess Med Ctr | Boston | Massachusetts | 02215 | — |
| Baystate Med Ctr of Springfield | Springfield | Massachusetts | 01199 | — |
| Robert Wood Johnson Med School/UMDNJ | New Brunswick | New Jersey | 089030019 | — |
| SUNY / Health Sciences Ctr at Brooklyn | Brooklyn | New York | 112032098 | — |
| SUNY / Erie County Med Ctr at Buffalo | Buffalo | New York | 14215 | — |
| Nassau County Med Ctr | East Meadow | New York | 11554 | — |
| Bellevue Hosp / New York Univ Med Ctr | New York | New York | 10016 | — |
| Saint Luke's - Roosevelt Hosp Ctr | New York | New York | 10025 | — |
| Columbia Presbyterian Med Ctr | New York | New York | 100323784 | — |
| Univ of Rochester Medical Center | Rochester | New York | 14642 | — |
| SUNY / State Univ of New York | Syracuse | New York | 13210 | — |
| Bronx Municipal Hosp Ctr/Jacobi Med Ctr | The Bronx | New York | 10461 | — |
| Montefiore Drug Treatment Ctr / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Montefiore Family Health Ctr / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Samaritan Village Inc / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Jack Weiler Hosp / Bronx Municipal Hosp | The Bronx | New York | 10465 | — |
| Montefiore Med Ctr / Bronx Municipal Hosp | The Bronx | New York | 10467 | — |
| Montefiore Med Ctr Adolescent AIDS Program | The Bronx | New York | 10467 | — |
| North Central Bronx Hosp / Bronx Municipal Hosp | The Bronx | New York | 10467 | — |
| Univ of North Carolina | Chapel Hill | North Carolina | 275997215 | — |
| Wake Med Ctr / Univ of North Carolina | Chapel Hill | North Carolina | 275997215 | — |
| Carolinas Med Ctr | Charlotte | North Carolina | 28203 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Univ of Pennsylvania at Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson Univ Hosp | Philadelphia | Pennsylvania | 191075098 | — |
| Med Univ of South Carolina / UNC | Charleston | South Carolina | 29425 | — |
| Northwest Family Ctr at the Harbor View Med Ctr | Seattle | Washington | 98104 | — |
| Univ of Washington | Seattle | Washington | 981224304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000648, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 27, 2021 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000648 live on ClinicalTrials.gov.