A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients
Public ClinicalTrials.gov record NCT00000655. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind Study of 566C80 Versus Septra (Trimethoprim/Sulfamethoxazole) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the effectiveness of atovaquone (566C80) compared to a standard antipneumocystis agent, (SMX/TMP), for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients. To compare the safety of short-term (21 days) treatment with 566C80 and SMX/TMP in AIDS patients with an acute episode of PCP. Standard therapies for acute treatment of PCP involve either SMX/TMP or pentamidine isetionate. Although both treatments are equally effective, side effects prevent completion of therapy in 11-55 percent of patients.
Study identification
- NCT ID
- NCT00000655
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Jan 1992 (Actual)
- Completion
- Not listed
- Last update posted
- Mar 1, 2011
United States locations
- U.S. sites
- 27
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Kaiser Foundation Hosp | Harbor City | California | 90710 | — |
| USC | Los Angeles | California | 90033 | — |
| Dr Richard Meyer | Los Angeles | California | 90048 | — |
| UCLA CARE Ctr | Los Angeles | California | 90095 | — |
| Infectious Disease Med Group | Oakland | California | 94609 | — |
| Univ of California / San Diego Treatment Ctr | San Diego | California | 921036325 | — |
| San Francisco Gen Hosp | San Francisco | California | 941102859 | — |
| UCSF - San Francisco Gen Hosp | San Francisco | California | 94110 | — |
| Dr Marcus Conant | San Francisco | California | 94115 | — |
| Georgetown Univ Med Ctr | Washington D.C. | District of Columbia | 20007 | — |
| Veterans Administration Med Ctr | Washington D.C. | District of Columbia | 20422 | — |
| Dr Winkler Weinberg | Roswell | Georgia | 30076 | — |
| Johns Hopkins Univ School of Medicine | Baltimore | Maryland | 21205 | — |
| Natl Inst of Allergy & Infect Dis / Cln Ctr | Bethesda | Maryland | 20892 | — |
| Washington Univ School of Medicine | St Louis | Missouri | 63108 | — |
| Beth Israel Med Ctr / Peter Krueger Clinic | New York | New York | 10003 | — |
| Saint Vincent's Hosp and Med Ctr | New York | New York | 10011 | — |
| Harlem AIDS Treatment Group / Harlem Hosp Ctr | New York | New York | 10037 | — |
| Duke Univ Med Ctr | Durham | North Carolina | 27710 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Good Samaritan Hosp | Portland | Oregon | 972103079 | — |
| Buckley Braffman Stern Med Associates | Philadelphia | Pennsylvania | 19107 | — |
| Regional Med Ctr at Memphis | Memphis | Tennessee | 38103 | — |
| The Regional Medical Ctr, Memphis | Memphis | Tennessee | 38105 | — |
| Plaza Med Ctr | Houston | Texas | 77004 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000655, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2011 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000655 live on ClinicalTrials.gov.