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Completed Phase 2 Interventional

A Multicenter Trial To Evaluate Oral Retrovir in the Treatment of Children With Symptomatic HIV Infection

ClinicalTrials.gov ID: NCT00000716

Public ClinicalTrials.gov record NCT00000716. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 4:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To evaluate the safety and tolerance of oral zidovudine (AZT) when given over a period of 24 weeks to children between 3 months and 12 years of age. The effectiveness of AZT in treating HIV infection in infants and children will also be evaluated. HIV infection in children is most often associated with symptomatic disease and poor prognosis. Treatment with antiviral therapy may be effective in altering the course of the disease and decreasing mortality in these children. AZT has been shown to be effective in certain adult patients with symptomatic HIV infection. It is therefore likely that infected children may also benefit from this treatment.

Study identification

NCT ID
NCT00000716
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
70 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
3 Months to 12 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Dec 31, 1990
Completion
Not listed
Last update posted
Mar 13, 2011

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Los Angeles County - USC Med Ctr Los Angeles California 90033
San Francisco AIDS Clinic / San Francisco Gen Hosp San Francisco California 941102859
Univ of Miami School of Medicine Miami Florida 331361013
Johns Hopkins Hosp - Pediatric Baltimore Maryland 212874933
Johns Hopkins Hosp Baltimore Maryland 21287
Children's Hosp of Boston Boston Massachusetts 021155724
Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl Newark New Jersey 071072198
Bellevue Hosp / New York Univ Med Ctr New York New York 10016
Duke Univ Med Ctr Durham North Carolina 27710

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000716, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 13, 2011 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00000716 live on ClinicalTrials.gov.

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