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Completed Phase 1 Interventional

A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3

ClinicalTrials.gov ID: NCT00000755

Public ClinicalTrials.gov record NCT00000755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 12:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To examine the response of HIV-1 infected patients to vaccination with gp120/HIV-1MN antigen. To determine the effect of antiretroviral therapy on vaccine responsiveness. Fifty percent of HIV-1 infected individuals remain symptom free for 8-12 years. It has been hypothesized that HIV-specific immune responses are responsible for the period of relative quiescence of viral replication. Recent studies suggest that these immune functions can be augmented by vaccination with HIV-derived antigens.

Study identification

NCT ID
NCT00000755
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
168 participants

Conditions and interventions

Conditions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
13 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Feb 28, 1993
Last update posted
Nov 3, 2021

Ends 1993

United States locations

U.S. sites
10
U.S. states
5
U.S. cities
7
Facility City State ZIP Site status
UCLA CARE Center CRS Los Angeles California 90095 —
Stanford CRS Palo Alto California 943055107 —
Ucsf Aids Crs San Francisco California 941102859 —
University of Colorado Hospital CRS Aurora Colorado 80262 —
Massachusetts General Hospital ACTG CRS Boston Massachusetts 02114 —
Bmc Actg Crs Boston Massachusetts 02118 —
Beth Israel Deaconess - East Campus A0102 CRS Boston Massachusetts 02215 —
Beth Israel Deaconess Med. Ctr., ACTG CRS Boston Massachusetts 02215 —
NY Univ. HIV/AIDS CRS New York New York 10016 —
University of Washington AIDS CRS Seattle Washington 981224304 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 3, 2021 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00000755 live on ClinicalTrials.gov.

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