A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and Didanosine
Public ClinicalTrials.gov record NCT00000770. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To assess the safety and toxicity of zidovudine (AZT)/didanosine (ddI) versus AZT/ddI combined with nevirapine in HIV-infected patients, and to obtain preliminary anti-HIV activity data using immunologic and virologic markers. Previous in vitro studies suggest that HIV that has already developed resistance to AZT and ddI is less able to develop resistance to nevirapine, a non-nucleoside reverse transcriptase inhibitor. Thus, convergent combination therapy with these three drugs in HIV-infected patients may prove more effective.
Study identification
- NCT ID
- NCT00000770
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Nov 1994 (Actual)
- Last update posted
- Nov 4, 2021
Ends 1994
United States locations
- U.S. sites
- 44
- U.S. states
- 14
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Univ of Southern California / LA County USC Med Ctr | Los Angeles | California | 900331079 | — |
| Highland Gen Hosp / San Francisco Gen Hosp | Oakland | California | 946021018 | — |
| Summitt Med Ctr / San Francisco Gen Hosp | Oakland | California | 94609 | — |
| Univ of California / San Diego Treatment Ctr | San Diego | California | 921036325 | — |
| San Francisco AIDS Clinic / San Francisco Gen Hosp | San Francisco | California | 941102859 | — |
| San Francisco Gen Hosp | San Francisco | California | 941102859 | — |
| Univ of Colorado Health Sciences Ctr | Denver | Colorado | 80262 | — |
| Univ of Miami School of Medicine | Miami | Florida | 331361013 | — |
| Northwestern Univ Med School | Chicago | Illinois | 60611 | — |
| Cook County Hosp | Chicago | Illinois | 60612 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Indiana Univ Hosp | Indianapolis | Indiana | 462025250 | — |
| Univ of Iowa Hosp and Clinic | Iowa City | Iowa | 52242 | — |
| Harvard (Massachusetts Gen Hosp) | Boston | Massachusetts | 02114 | — |
| Boston Med Ctr | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess - West Campus | Boston | Massachusetts | 02215 | — |
| Beth Israel Deaconess Med Ctr | Boston | Massachusetts | 02215 | — |
| Hennepin County Med Clinic | Minneapolis | Minnesota | 55415 | — |
| Univ of Minnesota | Minneapolis | Minnesota | 55455 | — |
| St Paul Ramsey Med Ctr | Saint Paul | Minnesota | 55101 | — |
| Univ of Nebraska Med Ctr | Omaha | Nebraska | 681985130 | — |
| City Hosp Ctr at Elmhurst / Mount Sinai Hosp | Elmhurst | New York | 11373 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Saint Clare's Hosp and Health Ctr | New York | New York | 10019 | — |
| Cornell Univ Med Ctr | New York | New York | 10021 | — |
| Mem Sloan - Kettering Cancer Ctr | New York | New York | 10021 | — |
| Mount Sinai Med Ctr | New York | New York | 10029 | — |
| Bronx Municipal Hosp Ctr/Jacobi Med Ctr | The Bronx | New York | 10461 | — |
| Comprehensive Health Care Ctr / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Montefiore Drug Treatment Ctr / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Montefiore Family Health Ctr / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Samaritan Village Inc / Bronx Municipal Hosp | The Bronx | New York | 10461 | — |
| Jack Weiler Hosp / Bronx Municipal Hosp | The Bronx | New York | 10465 | — |
| Montefiore Med Ctr / Bronx Municipal Hosp | The Bronx | New York | 10467 | — |
| North Central Bronx Hosp / Bronx Municipal Hosp | The Bronx | New York | 10467 | — |
| Univ of North Carolina | Chapel Hill | North Carolina | 275997215 | — |
| Carolinas Med Ctr | Charlotte | North Carolina | 28203 | — |
| Moses H Cone Memorial Hosp | Greensboro | North Carolina | 27401 | — |
| Wake County Dept of Health | Raleigh | North Carolina | 27610 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Girard Med Ctr | Philadelphia | Pennsylvania | 191046073 | — |
| Univ of Pennsylvania at Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson Univ Hosp | Philadelphia | Pennsylvania | 191075098 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000770, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2021 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000770 live on ClinicalTrials.gov.