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Completed Phase 2 Interventional

The Effectiveness of GM-CSF in HIV-Positive Patients Who Are Also Receiving Anti-HIV Therapy

ClinicalTrials.gov ID: NCT00000850

Public ClinicalTrials.gov record NCT00000850. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 9:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The Effects of GM-CSF on Plasma HIV-1 RNA and Chemokine Receptor Expression in HIV-1 Infected Subjects Receiving Concomitant Potent Antiretroviral Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to see how HIV-positive patients who are taking anti-HIV drugs and have a viral load (level of HIV in the blood) of 1,500 copies/ml or more respond to GM-CSF (granulocyte-macrophage colony-stimulating factor). GM-CSF is a medication that is being tested in HIV-positive patients to see if it can improve their immune systems or if it can lower the level of HIV in their blood. GM-CSF is often given to patients with leukemia or patients who have received bone marrow transplants to increase their white blood cells and to improve their immune systems. Doctors believe that GM-CSF can increase CD4 counts in HIV-positive patients, but this study will also look at how GM-CSF affects viral load.

Study identification

NCT ID
NCT00000850
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
108 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Nov 30, 2003
Last update posted
Oct 28, 2021

Ends 2003

United States locations

U.S. sites
39
U.S. states
16
U.S. cities
25
Facility City State ZIP Site status
Univ of Alabama at Birmingham Birmingham Alabama 35294
Kaiser Permanente LAMC Los Angeles California 90027
UCLA CARE Ctr Los Angeles California 90095
Willow Clinic Menlo Park California 94025
Univ of California / San Diego Treatment Ctr San Diego California 921036325
San Francisco Gen Hosp San Francisco California 941102859
Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium San Jose California 951282699
Marin County Specialty Clinic San Rafael California 94903
San Mateo AIDS Program / Stanford Univ Stanford California 943055107
Stanford Univ Med Ctr Stanford California 943055107
Harbor UCLA Med Ctr Torrance California 90502
Univ of Colorado Health Sciences Ctr Denver Colorado 80262
Univ of Miami School of Medicine Miami Florida 331361013
Univ of Hawaii Honolulu Hawaii 96816
Northwestern Univ Med School Chicago Illinois 60611
Cook County Hosp Chicago Illinois 60612
Rush Presbyterian - Saint Luke's Med Ctr Chicago Illinois 60612
Indiana Univ Hosp Indianapolis Indiana 462025250
Division of Inf Diseases/ Indiana Univ Hosp Indianapolis Indiana 46202
Methodist Hosp of Indiana / Life Care Clinic Indianapolis Indiana 46202
Boston Med Ctr Boston Massachusetts 02118
Beth Israel Deaconess - West Campus Boston Massachusetts 02215
St Louis Regional Hosp / St Louis Regional Med Ctr St Louis Missouri 63112
Bellevue Hosp / New York Univ Med Ctr New York New York 10016
Aaron Diamond AIDS Rsch Ctr / Rockefeller Univ New York New York 10021
Chelsea Ctr New York New York 10021
Cornell Univ Med Ctr New York New York 10021
Mount Sinai Med Ctr New York New York 10029
Columbia Presbyterian Med Ctr New York New York 10032
Univ of North Carolina Chapel Hill North Carolina 275997215
Duke Univ Med Ctr Durham North Carolina 27710
Case Western Reserve Univ Cleveland Ohio 44106
MetroHealth Med Ctr Cleveland Ohio 441091998
Ohio State Univ Hosp Clinic Columbus Ohio 432101228
Philadelphia Veterans Administration Med Ctr Philadelphia Pennsylvania 19104
Univ of Pennsylvania at Philadelphia Philadelphia Pennsylvania 19104
Julio Arroyo West Columbia South Carolina 29169
Univ of Texas Galveston Galveston Texas 775550435
Univ of Washington Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000850, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 28, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00000850 live on ClinicalTrials.gov.

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