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Completed Not applicable Interventional

A Study to Evaluate the Safety and Tolerability of Zidovudine (ZDV) in Premature Infants Born to HIV-Positive Women.

ClinicalTrials.gov ID: NCT00000855

Public ClinicalTrials.gov record NCT00000855. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 8:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The Safety, Tolerance, and Pharmacokinetics of Zidovudine in Premature Infants Exposed to HIV.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to examine the safety and tolerability of ZDV when given to premature infants born to HIV-positive women to prevent HIV infection. ZDV has been used successfully to prevent the transmission of HIV from mother to child during pregnancy and birth. However, ZDV has been given to very few premature babies, and the best dose to use has not yet been determined.

Study identification

NCT ID
NCT00000855
Recruitment status
Completed
Study type
Interventional
Phase
Not applicable
Enrollment
35 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Day to 5 Days
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Jan 31, 2000
Last update posted
Oct 27, 2021

Ends 2000

United States locations

U.S. sites
35
U.S. states
16
U.S. cities
28
Facility City State ZIP Site status
Univ of Alabama at Birmingham - Pediatric Birmingham Alabama 35233
Phoenix Childrens Hosp Phoenix Arizona 85006
UCSD Med Ctr / Pediatrics / Clinical Sciences La Jolla California 920930672
Los Angeles County - USC Med Ctr Los Angeles California 90033
UCLA Med Ctr / Pediatric Los Angeles California 900951752
Harbor - UCLA Med Ctr / UCLA School of Medicine Los Angeles California 905022004
Children's Hosp of Oakland Oakland California 946091809
San Francisco Gen Hosp San Francisco California 94110
UCSF / Moffitt Hosp - Pediatric San Francisco California 941430105
Univ of Florida Gainesville Gainesville Florida 32610
Univ of Florida Health Science Ctr / Pediatrics Jacksonville Florida 32209
Univ of Miami / Jackson Memorial Hosp Miami Florida 33136
Univ of Miami (Pediatric) Miami Florida 33161
Emory Univ Hosp / Pediatrics Atlanta Georgia 30306
Univ of Illinois College of Medicine / Pediatrics Chicago Illinois 60612
Univ of Chicago Children's Hosp Chicago Illinois 606371470
Division of Inf Diseases/ Indiana Univ Hosp Indianapolis Indiana 46202
Children's Hosp of Boston Boston Massachusetts 021155724
Boston City Hosp / Pediatrics Boston Massachusetts 02118
Univ of Massachusetts Med School Worcester Massachusetts 016550001
Univ of Mississippi Med Ctr Jackson Mississippi 39213
Univ of Medicine & Dentistry of New Jersey / Univ Hosp Newark New Jersey 071032714
Children's Hosp at Albany Med Ctr Albany New York 12208
Columbia Presbyterian Med Ctr New York New York 10032
Harlem Hosp Ctr New York New York 10037
Univ of Rochester Med Ctr Rochester New York 146420001
State Univ of New York at Stony Brook Stony Brook New York 117948111
SUNY Health Sciences Ctr at Syracuse / Pediatrics Syracuse New York 13210
Westchester Hosp Valhalla New York 10595
Duke Univ Med Ctr Durham North Carolina 277103499
Med Univ of South Carolina Charleston South Carolina 294253312
Children's Med Ctr of Dallas Dallas Texas 75235
Children's Hosp of the King's Daughters Norfolk Virginia 23507
Med College of Virginia Richmond Virginia 23219
Children's Hospital & Medical Center / Seattle ACTU Seattle Washington 981050371

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000855, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 27, 2021 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00000855 live on ClinicalTrials.gov.

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