A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children With Prior Treatment
Public ClinicalTrials.gov record NCT00000902. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RAD-1: A Phase I/II Antiretroviral Management Algorithm for Pediatric Subjects of Four-Drug Combination Therapies Based on Prior Antiretroviral Experience
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the value of changing anti-HIV medications in children with progressive HIV disease who have received previous treatment. Plasma viral load (the level of HIV in the blood) is probably most effectively reduced by giving patients anti-HIV drugs which affect the virus at various stages of development. Changing the medications may enhance the results of treatment.
Study identification
- NCT ID
- NCT00000902
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 217 participants
Conditions and interventions
Conditions
Interventions
- Ritonavir Drug
- Nelfinavir mesylate Drug
- Nevirapine Drug
- Lamivudine Drug
- Stavudine Drug
- Zidovudine Drug
- Zalcitabine Drug
- Didanosine Drug
Drug
Eligibility (public fields only)
- Age range
- 6 Months to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Apr 2002 (Actual)
- Last update posted
- Oct 29, 2021
Ends 2002
United States locations
- U.S. sites
- 59
- U.S. states
- 21
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham - Pediatric | Birmingham | Alabama | 35233 | — |
| Univ of South Alabama | Mobile | Alabama | 36604 | — |
| UCSD Med Ctr / Pediatrics / Clinical Sciences | La Jolla | California | 920930672 | — |
| Long Beach Memorial (Pediatric) | Long Beach | California | 90801 | — |
| Los Angeles County - USC Med Ctr | Los Angeles | California | 90033 | — |
| Cedars Sinai / UCLA Med Ctr Cedars-Sinai Medical Center | Los Angeles | California | 900481804 | — |
| Harbor - UCLA Med Ctr / UCLA School of Medicine | Los Angeles | California | 905022004 | — |
| Children's Hosp of Oakland | Oakland | California | 946091809 | — |
| UCSF / Moffitt Hosp - Pediatric | San Francisco | California | 941430105 | — |
| Children's Hosp of Denver | Denver | Colorado | 802181088 | — |
| Connecticut Children's Med Ctr | Farmington | Connecticut | 060303805 | — |
| Yale Univ Med School | New Haven | Connecticut | 06504 | — |
| Howard Univ Hosp | Washington D.C. | District of Columbia | 20060 | — |
| North Broward Hosp District | Fort Lauderdale | Florida | 33311 | — |
| Univ of Florida Health Science Ctr / Pediatrics | Jacksonville | Florida | 32209 | — |
| Univ of Miami (Pediatric) | Miami | Florida | 33161 | — |
| Emory Univ Hosp / Pediatrics | Atlanta | Georgia | 30306 | — |
| Med College of Georgia | Augusta | Georgia | 30912 | — |
| The Med Ctr Inc | Columbus | Georgia | 31901 | — |
| Cook County Hosp | Chicago | Illinois | 60612 | — |
| Univ of Illinois College of Medicine / Pediatrics | Chicago | Illinois | 60612 | — |
| Chicago Children's Memorial Hosp | Chicago | Illinois | 606143394 | — |
| Tulane Univ / Charity Hosp of New Orleans | New Orleans | Louisiana | 701122699 | — |
| Univ of Maryland at Baltimore / Univ Med Ctr | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hosp - Pediatric | Baltimore | Maryland | 212874933 | — |
| Children's Hosp of Boston | Boston | Massachusetts | 021155724 | — |
| Boston City Hosp / Pediatrics | Boston | Massachusetts | 02118 | — |
| Baystate Med Ctr of Springfield | Springfield | Massachusetts | 01199 | — |
| Univ of Massachusetts Med School | Worcester | Massachusetts | 016550001 | — |
| Univ of Mississippi Med Ctr | Jackson | Mississippi | 39213 | — |
| UMDNJ - Robert Wood Johnson Med School / Pediatrics | New Brunswick | New Jersey | 089030019 | — |
| Univ of Medicine & Dentistry of New Jersey / Univ Hosp | Newark | New Jersey | 071032714 | — |
| Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl | Newark | New Jersey | 07103 | — |
| Children's Hosp at Albany Med Ctr | Albany | New York | 12208 | — |
| SUNY - Brooklyn | Brooklyn | New York | 11203 | — |
| North Shore Univ Hosp | Great Neck | New York | 11021 | — |
| Schneider Children's Hosp | New Hyde Park | New York | 11040 | — |
| Bellevue Hosp / New York Univ Med Ctr | New York | New York | 10016 | — |
| Cornell Univ Med College | New York | New York | 10021 | — |
| Metropolitan Hosp Ctr | New York | New York | 10029 | — |
| Columbia Presbyterian Med Ctr | New York | New York | 10032 | — |
| Incarnation Children's Ctr / Columbia Presbyterian Med Ctr | New York | New York | 10032 | — |
| Harlem Hosp Ctr | New York | New York | 10037 | — |
| Univ of Rochester Med Ctr | Rochester | New York | 146420001 | — |
| State Univ of New York at Stony Brook | Stony Brook | New York | 117948111 | — |
| SUNY Health Sciences Ctr at Syracuse / Pediatrics | Syracuse | New York | 13210 | — |
| Bronx Lebanon Hosp Ctr | The Bronx | New York | 10457 | — |
| Duke Univ Med Ctr | Durham | North Carolina | 277103499 | — |
| Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr | Durham | North Carolina | 27710 | — |
| Columbus Children's Hosp | Columbus | Ohio | 432052696 | — |
| Children's Hosp of Philadelphia | Philadelphia | Pennsylvania | 191044318 | — |
| Saint Christopher's Hosp for Children | Philadelphia | Pennsylvania | 191341095 | — |
| Med Univ of South Carolina | Charleston | South Carolina | 294253312 | — |
| Saint Jude Children's Research Hosp of Memphis | Memphis | Tennessee | 381052794 | — |
| Vanderbilt Univ Med Ctr | Nashville | Tennessee | 372322581 | — |
| Children's Med Ctr of Dallas | Dallas | Texas | 75235 | — |
| Texas Children's Hosp / Baylor Univ | Houston | Texas | 77030 | — |
| Children's Hosp of the King's Daughters | Norfolk | Virginia | 23507 | — |
| Med College of Virginia | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000902, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2021 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000902 live on ClinicalTrials.gov.